Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sigmar Dressler"'
Autor:
Martin Klumpp, Michael Habig, David Beer, Sigmar Dressler, Viral Patel, Anke Blechschmidt, Christian Ostermeier, Andreas Billich, Barbara Hess
Publikováno v:
SLAS Discovery. 14:679-689
High-throughput screening often identifies not only specific, stoichiometrically binding inhibitors but also undesired com- pounds that unspecifically interfere with the targeted activity by nonstoichiometrically binding, unfolding, and/or inactivat-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74e76fb77ae7cddc198e91427e7912a1
https://doi.org/10.1177/1087057109336586
https://doi.org/10.1177/1087057109336586
Autor:
Sigmar Dressler, Walter Thiel
Publikováno v:
Chemical Physics Letters. 273:71-78
A finite difference procedure has been implemented for calculating anharmonic force fields by density functional theory The numerical precision of this approach is investigated, and guidelines are recommended. Comparisons with experiment and ab initi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9f662b4b68ade76c7cb695fa00d76ef
https://doi.org/10.1016/s0009-2614(97)00552-6
https://doi.org/10.1016/s0009-2614(97)00552-6
Autor:
Kamal Azzaoui, Ansgar Schuffenhauer, Meir Glick, Sigmar Dressler, Edgar Jacoby, John W. Davies, Jeremy L. Jenkins, Maxim Popov, Silvio Roggo
Publikováno v:
Chemogenomics: Knowledge-based Approaches to Drug Discovery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a8944a23a6bed45e4964b09feb39d8a
https://doi.org/10.1142/9781860948114_0001
https://doi.org/10.1142/9781860948114_0001
Publikováno v:
High-Throughput Screening in Drug Discovery; 2006, p151-205, 56p
Publikováno v:
International Journal of Quantum Chemistry; Dec1995, Vol. 56 Issue 6, p861-873, 13p
Autor:
Edgar Jacoby
In the post-genomic era, one of the key challenges for drug discovery is making optimal use of the comprehensive genomic data available after the elucidation of the human genome and others in order to identify effective new medicines. Addressing this
Autor:
Jörg Hüser
Backed by leading authorities, this is a professional guide to successful compound screening in pharmaceutical research and chemical biology, including the chemoinformatic tools needed for correct data evaluation. Chapter authors from leading pharmac