Deciphering the essentiality and function of the anti‐σ M factors in Bacillus subtilis

Autor: Daniel M. Roistacher, John D. Helmann, Heng Zhao

Publikováno v: Mol Microbiol

Bacteria use alternative sigma factors to adapt to different growth and stress conditions. The Bacillus subtilis extracytoplasmic function (ECF) sigma factor SigM regulates genes for cell wall synthesis and is crucial for maintaining cell wall homeos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e46a1947cb96b97dc45befe62e798bf
https://doi.org/10.1111/mmi.14216

The anti-sigma factor MucA is required for viability in Pseudomonas aeruginosa

Autor: Melissa C. Schofield, Daniela Rodriguez, Amanda A. Kidman, Erin K. Cassin, Lia A. Michaels, Elizabeth A. Campbell, Peter A. Jorth, Boo Shan Tseng

During decades-long infections in the cystic fibrosis (CF) airway, Pseudomonas aeruginosa undergoes selection. One bacterial genetic adaptation often observed in CF isolates is mucA mutations. MucA inhibits the sigma factor AlgU. Mutations in mucA le

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ce8e76257ea02948788450076a2fe78c
https://doi.org/10.1101/2020.08.17.253617

Diverse mechanisms regulate sporulation sigma factor activity in the Firmicutes

Autor: Kelly A. Fimlaid, Aimee Shen

Publikováno v: Current Opinion in Microbiology. 24:88-95

Sporulation allows bacteria to survive adverse conditions and is essential to the lifecycle of some obligate anaerobes. In Bacillus subtilis, the sporulation-specific sigma factors, σ(F), σ(E), σ(G), and σ(K), activate compartment-specific transc

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https://doi.org/10.1016/j.mib.2015.01.006

Self-cleavage of the Pseudomonas aerugginosa cell-surface signaling anti-sigma factor FoxR occurs through an N-O acyl rearrangement

Autor: Wilbert Bitter, Maikel Wijtmans, Karlijn C. Bastiaansen, María A. Llamas, Peter van Ulsen

Publikováno v: Journal of Biological Chemistry, 290(19), 12237-12246. American Society for Biochemistry and Molecular Biology Inc.
Bastiaansen, K C J T, van Ulsen, P, Wijtmans, M, Bitter, W & Llamas, M A 2015, ' Self-cleavage of the Pseudomonas aerugginosa cell-surface signaling anti-sigma factor FoxR occurs through an N-O acyl rearrangement. ', Journal of Biological Chemistry, vol. 290, no. 19, pp. 12237-12246 . https://doi.org/10.1074/jbc.M115.643098
Bastiaansen, K C J T, van Ulsen, P, Wijtmans, M, Bitter, W & Llamas, M A 2015, ' Self-cleavage of the Pseudomonas aeruginosa Cell-surface Signaling Anti-sigma Factor FoxR Occurs through an N-O Acyl Rearrangement. ', Journal of Biological Chemistry, vol. 290, no. 19, pp. 12237-12246 . https://doi.org/10.1074/jbc.M115.643098

The Fox system of Pseudomonas aeruginosa is a cell-surface signaling (CSS) pathway employed by the bacterium to sense and respond to the presence of the heterologous siderophore ferrioxamine in the environment. This regulatory pathway controls the tr

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https://research.vu.nl/en/publications/f6c2a03a-e66f-4c05-a405-1bdfd9cd8ed0

Role of Autoregulation and Relative Synthesis of Operon Partners in Alternative Sigma Factor Networks

Autor: Jatin Narula, Oleg A. Igoshin, Abhinav Tiwari

Publikováno v: PLoS Computational Biology
PLoS Computational Biology, Vol 12, Iss 12, p e1005267 (2016)

Despite the central role of alternative sigma factors in bacterial stress response and virulence their regulation remains incompletely understood. Here we investigate one of the best-studied examples of alternative sigma factors: the σB network that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c82987dde26070045f8d070e9b0aac7b
https://pubmed.ncbi.nlm.nih.gov/27977677