Sleep-controlling neurons are sensitive and vulnerable to multiple forms of α-synuclein:implications for the early appearance of sleeping disorders in α-synucleinopathies

Autor: Altair B Dos Santos, Line K Skaanning, Siggania Thaneskwaran, Eyd Mikkelsen, Cesar R Romero-Leguizamon, Thomas Skamris, Morten P Kristensen, Annette E Langkilde, Kristi A. Kohlmeier

Publikováno v: Dos Santos, A B, Skaanning, L K, Thaneshwaran, S, Mikkelsen, E, Romero-Leguizamón, C R, Skamris, T, Kristensen, M P, Langkilde, A E & Kohlmeier, K A 2022, ' Sleep-controlling neurons are sensitive and vulnerable to multiple forms of α-synuclein : implications for the early appearance of sleeping disorders in α-synucleinopathies ', Cellular and Molecular Life Sciences, vol. 79, no. 8, 450 . https://doi.org/10.1007/s00018-022-04467-z

Parkinson’s disease, Multiple System Atrophy, and Lewy Body Dementia are incurable diseases called α-synucleinopathies as they are mechanistically linked to the protein, α-synuclein (α-syn). α-syn exists in different structural forms which have

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https://curis.ku.dk/portal/da/publications/sleepcontrolling-neurons-are-sensitive-and-vulnerable-to-multiple-forms-of-synuclein(efd99af7-2118-43ca-ac03-633180d79d60).html