Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Sige Zou"'
Autor:
Seung Kyu Lee, Yutong Xue, Weiping Shen, Yongqing Zhang, Yuyoung Joo, Muzammil Ahmad, Madoka Chinen, Yi Ding, Wai Lim Ku, Supriyo De, Elin Lehrmann, Kevin G. Becker, Elissa P. Lei, Keji Zhao, Sige Zou, Alexei Sharov, Weidong Wang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Topoisomerases solve topological problems during DNA metabolism, but their role in RNA metabolism remains unclear. Here the authors provide evidence that in Drosophila, Topoisomerase 3β interacts biochemically and genetically with the RNAi-induced s
Externí odkaz:
https://doaj.org/article/35a40d0fb3f544fea381f448c5f2549b
Autor:
Xiaoping Sun, Charles T. Wheeler, Jason Yolitz, Mara Laslo, Thomas Alberico, Yaning Sun, Qisheng Song, Sige Zou
Publikováno v:
Cell Reports, Vol 8, Iss 6, Pp 1781-1792 (2014)
Diet composition is a critical determinant of lifespan, and nutrient imbalance is detrimental to health. However, how nutrients interact with genetic factors to modulate lifespan remains elusive. We investigated how diet composition influences mitoch
Externí odkaz:
https://doaj.org/article/b3e12ef6a14a4caea559de1248b6fe43
Publikováno v:
BioTechniques, Vol 43, Iss 1, Pp 93-98 (2007)
The DNA binding protein nuclear factor κB (NF-κB) and the cellular signaling pathways in which it participates are the central coordinators of many biological processes, including innate and adaptive immune responses, oxidative stress response, and
Externí odkaz:
https://doaj.org/article/b475c59b03354ef39799aa74f3d3d4e3
Autor:
Bin Yan, Huai Li, Xinping Yang, Jiaofang Shao, Minyoung Jang, Daogang Guan, Sige Zou, Carter Van Waes, Zhong Chen, Ming Zhan
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73656 (2013)
In head and neck squamous cell carcinoma (HNSCC), mutations of p53 usually coexist with aberrant activation of NF-kappaB (NF-κB), other transcription factors and microRNAs, which promote tumor pathogenesis. However, how these factors and microRNAs i
Externí odkaz:
https://doaj.org/article/8631c5ebcaa84e679dccf79af4f3659c
Autor:
Yuyoung Joo, Elin Lehrmann, Wai Lim Ku, Elissa P. Lei, Kevin G. Becker, Supriyo De, Alexei A. Sharov, Madoka Chinen, Yutong Xue, Weidong Wang, Yongqing Zhang, Weiping Shen, Yi Ding, Muzammil Ahmad, Keji Zhao, Seung Kyu Lee, Sige Zou
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Nature Communications
Nature Communications
Topoisomerases solve topological problems during DNA metabolism, but whether they participate in RNA metabolism remains unclear. Top3β represents a family of topoisomerases carrying activities for both DNA and RNA. Here we show that in Drosophila, T
Autor:
Sige Zou, Pablo Liedo, Leopoldo Altamirano-Robles, Janeth Cruz-Enriquez, Amy Morice, Donald K Ingram, Kevin Kaub, Nikos Papadopoulos, James R Carey
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18151 (2011)
Characterization of lifetime behavioral changes is essential for understanding aging and aging-related diseases. However, such studies are scarce partly due to the lack of efficient tools. Here we describe and provide proof of concept for a stereo vi
Externí odkaz:
https://doaj.org/article/d3bafd8b0c364658b6b5eada800d347e
Autor:
Judy L. Jensen, Mingjie Tang, Anhong Zhou, Qifei Li, Han Zhang, Xiaoping Sun, Theodore G. Liou, Sige Zou, Wei Zhang
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Biological Engineering Faculty Publications
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Biological Engineering Faculty Publications
Diesel exhaust particles (DEPs) are major air pollutants that lead to numerous human disorders, especially pulmonary diseases, partly through the induction of oxidative stress. Resveratrol is a polyphenol that ameliorates the production of reactive o
Publikováno v:
Nucleic Acids Research
Human cells contain five topoisomerases in the nucleus and cytoplasm, but which one is the major topoisomerase for mRNAs is unclear. To date, Top3β is the only known topoisomerase that possesses RNA topoisomerase activity, binds mRNA translation mac
Autor:
Ethan C. Wilson, Jessica Dinh, Cole G. Murbach, Yuqing Dong, Sige Zou, Sujay Guha, Min Cao, Ojas Natarajan
Publikováno v:
Nutrients, Vol 6, Iss 2, Pp 911-921 (2014)
Nutrients
Nutrients; Volume 6; Issue 2; Pages: 911-921
Nutrients
Nutrients; Volume 6; Issue 2; Pages: 911-921
Consumption of nutraceuticals is a major and potent dietary intervention for delaying aging. As the timing of administration is critical for the efficacy of bioactive compounds in medicine, the effectiveness of nutraceuticals may also be dramatically