Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Sifeng Chen"'
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-17 (2022)
Abstract Background Induced pluripotent stem cells (iPSCs) have the potential to promote wound healing; however, their adhesion to the extracellular matrix (ECM) might decrease iPSC migration, thereby limiting their therapeutic potential. Integrin β
Externí odkaz:
https://doaj.org/article/2606070f2e2e4b7babe6026d7267c25d
Autor:
Anfeng Cui, Shirui Li, Yijun Li, Dawei Yang, Jiongwei Huang, Xuemeng Wang, Nana Song, Fuchen Chen, Sifeng Chen, Meng Xiang
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The mortality rate associated with acute lung injury (ALI) and its severe form, acute respiratory distress syndrome, is high. Induced pluripotent stem cell (iPSC) therapy is a potential treatment method for ALI, but its therapeutic efficacy is limite
Externí odkaz:
https://doaj.org/article/bb99b6ca4dee4aada63ad52267d0fece
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-14 (2020)
Abstract Background Stem cells, including induced pluripotent stem cells (iPSCs), have tremendous potential in health care, though with several significant limitations. Each of the limitations, including immunogenicity, may block most of the therapeu
Externí odkaz:
https://doaj.org/article/5a8d7d508dd54fbfaf5b5e8d4576e508
Autor:
Xiuya Li, Fei Gao, Xiaochen Wang, Qianqian Liang, Aobing Bai, Zhuo Liu, Xinyun Chen, Ermin Li, Sifeng Chen, Chao Lu, Ruizhe Qian, Ning Sun, Ping Liang, Chen Xu
Publikováno v:
EBioMedicine, Vol 71, Iss , Pp 103575- (2021)
Background: Human sinoatrial cardiomyocytes are essential building blocks for cell therapies of conduction system disorders. However, current differentiation protocols for deriving nodal cardiomyocytes from human pluripotent stem cells (hPSCs) are ve
Externí odkaz:
https://doaj.org/article/6532b2e9d1914106998ef441702b2afb
Autor:
Meng Lu, Lu Peng, Xu Ming, Xiaokai Wang, Anfeng Cui, Yijun Li, Xinhong Wang, Dan Meng, Ning Sun, Meng Xiang, Sifeng Chen
Publikováno v:
EBioMedicine, Vol 42, Iss , Pp 443-457 (2019)
Background: Comparing non-inbred autologous and allogeneic induced pluripotent stem cells (iPSCs) and their secreted subcellular products among non-human primates is critical for choosing optimal iPSC products for human clinical trials. Methods: iPSC
Externí odkaz:
https://doaj.org/article/5850166182704239b7456921eedcf946
Autor:
Bin Li, Hui Yang, Xiaochen Wang, Yongkun Zhan, Wei Sheng, Huanhuan Cai, Haoyang Xin, Qianqian Liang, Ping Zhou, Chao Lu, Ruizhe Qian, Sifeng Chen, Pengyuan Yang, Jianyi Zhang, Weinian Shou, Guoying Huang, Ping Liang, Ning Sun
Publikováno v:
Stem Cell Research & Therapy, Vol 8, Iss 1, Pp 1-18 (2017)
Abstract Background Most infarctions occur in the left anterior descending coronary artery and cause myocardium damage of the left ventricle. Although current pluripotent stem cells (PSCs) and directed cardiac differentiation techniques are able to g
Externí odkaz:
https://doaj.org/article/4397c5766bbb4659bc63a2bdf6557e81
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Exosomes secreted by mesenchymal stem cells have shown great therapeutic potential in regenerative medicine. In this study, we performed meta-analysis to assess the clinical effectiveness of using exosomes in ischemia/reperfusion injury based on the
Externí odkaz:
https://doaj.org/article/4e58b0ad96dd4ec2a61a8af3cd0bb572
Publikováno v:
BioTechniques, Vol 37, Iss 1, Pp 84-89 (2004)
Endothelial cell dysfunction plays a critical role in the pathogenesis of cardiovascular diseases. Gene targeted mutant, knockout, or transgenic mice are widely used in the laboratory investigation of these disorders. We describe a simple and reprodu
Externí odkaz:
https://doaj.org/article/9db2472ae3ef400eb569cca08a47a337
Autor:
Ji-Hong Chen, Qian Zhang, Yuanjie Yu, Kongling Li, Hong Liao, Longying Jiang, Lu Hong, Xiaohui Du, Xinghai Hu, Sifeng Chen, Sheng Yin, Qingmin Gao, Xiangdong Yin, Hesheng Luo, Jan D Huizinga
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60474 (2013)
Better understanding of intrinsic control mechanisms of colonic motility will lead to better treatment options for colonic dysmotility. The aim was to investigate neurogenic and myogenic control mechanisms underlying pan-colonic motor patterns.Analys
Externí odkaz:
https://doaj.org/article/2517df9016754ffc9307c62bd1b2f260
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e48393 (2012)
Acute intensive insulin therapy causes a transient worsening of diabetic retinopathy in type 1 diabetes patients and is related to VEGF expression. Reactive oxygen species (ROS) have been shown to be involved in HIF-1α and VEGF expression induced by
Externí odkaz:
https://doaj.org/article/058d6558b8794ba7b064b39e59231609