Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sif Groth Rønn"'
Autor:
János Tibor Kodra, Cathrine Ørskov, Xiaoai Wu, Steffen Reedtz-Runge, Sif Groth Rønn, Prafull S. Gandhi, Stephanie Hennen, Vladyslav Soroka, Peter Kaastrup, Berit Olsen Krogh, Silvia Barbateskovic, Gerd Schluckebier
Publikováno v:
Scientific Reports
The Glucagon-like peptide-1 receptor (GLP-1R) is a member of the class B G protein-coupled receptor (GPCR) family and a well-established target for the treatment of type 2 diabetes. The N-terminal extracellular domain (ECD) of GLP-1R is important for
Autor:
Peter Brøgger, Lars Aagaard, H. D. Pedersen, Peter Bross, Sif Groth Rønn, Tino Klein, Charlotte Brandt Sørensen, Trine Skov Petersen, Rasha Abdelkadhem Al-Saaidi, Yan Zhou, Dianna Hussmann, Yonglun Luo, Yong Liu, Anders Lade Nielsen, Guangqian Zhou, Lin Lin, Shuang Tan, Lars Bolund
Publikováno v:
Zhou, Y, Liu, Y, Hussmann, D, Brøgger, P, Al-Saaidi, R A, Tan, S, Lin, L, Petersen, T S, Zhou, G Q, Bross, P, Aagaard, L, Klein, T, Rønn, S G, Pedersen, H D, Bolund, L, Nielsen, A L, Sørensen, C B & Luo, Y 2016, ' Enhanced genome editing in mammalian cells with a modified dual-fluorescent surrogate system ', Cellular and Molecular Life Sciences, vol. 73, no. 13, pp. 2543-63 . https://doi.org/10.1007/s00018-015-2128-3
Programmable DNA nucleases such as TALENs and CRISPR/Cas9 are emerging as powerful tools for genome editing. Dual-fluorescent surrogate systems have been demonstrated by several studies to recapitulate DNA nuclease activity and enrich for genetically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e40220a9109b2dfd8d54bcffbf05a291
https://pure.au.dk/portal/da/publications/enhanced-genome-editing-in-mammalian-cells-with-a-modified-dualfluorescent-surrogate-system(44e6d9fd-64a1-4f25-a66e-cff3c3f69c3b).html
https://pure.au.dk/portal/da/publications/enhanced-genome-editing-in-mammalian-cells-with-a-modified-dualfluorescent-surrogate-system(44e6d9fd-64a1-4f25-a66e-cff3c3f69c3b).html
Publikováno v:
Islets. 4(1)
The Reg3 peptides INGAP-PP and human Reg3α/β (HIP) have been hypothesized to stimulate β-cell neogenesis in the pancreas. Administration of INGAP-PP has been shown to cause an increase in β-cell mass in multiple animal models, reverse streptozoto