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Autor:
Sif Christine Lykke Hougaard, Geneviève Thon, Jan Fabio Nickels, Ala Trusina, Amanda Møller Mortensen, Kim Sneppen, Sebastian Jespersen Charlton, Ashleigh Katrine Edwards
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences
Nickels, J F, Edwards, A K, Charlton, S J, Mortensen, A M, Hougaard, S C L, Trusina, A, Sneppen, K & Thon, G 2021, ' Establishment of heterochromatin in domain-size-dependent bursts ', Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 15, e2022887118 . https://doi.org/10.1073/pnas.2022887118
Proceedings of the National Academy of Sciences
Nickels, J F, Edwards, A K, Charlton, S J, Mortensen, A M, Hougaard, S C L, Trusina, A, Sneppen, K & Thon, G 2021, ' Establishment of heterochromatin in domain-size-dependent bursts ', Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 15, e2022887118 . https://doi.org/10.1073/pnas.2022887118
Significance How repressive heterochromatic states propagate along chromosomes and are subsequently maintained for many cell divisions remain important unanswered questions in biology. Combining mathematical modeling and single-cell measurements, we