Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Siewert-Jan Marrink"'
Autor:
Claire E. Price, Filipe Branco dos Santos, Anne Hesseling, Jaakko J. Uusitalo, Herwig Bachmann, Vera Benavente, Anisha Goel, Jan Berkhout, Frank J. Bruggeman, Siewert-Jan Marrink, Manolo Montalban-Lopez, Anne de Jong, Jan Kok, Douwe Molenaar, Bert Poolman, Bas Teusink, Oscar P. Kuipers
Publikováno v:
BMC Evolutionary Biology, Vol 19, Iss 1, Pp 1-15 (2019)
Abstract Background A central theme in (micro)biology is understanding the molecular basis of fitness i.e. which strategies are successful under which conditions; how do organisms implement such strategies at the molecular level; and which constraint
Externí odkaz:
https://doaj.org/article/268f290335c04c76aeea5bce0f5b920b
Publikováno v:
Biophysical Journal.
Association of the cellular adhesive protein CD44 and the N-terminal (FERM) domain of cytoskeleton adaptors is critical for cell proliferation, migration and signaling. Phosphorylation of the cytoplasmic domain (CTD) of CD44 acts as an important regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e86f737511140bb05bb9bce9a100ba
https://doi.org/10.1016/j.bpj.2023.05.021
https://doi.org/10.1016/j.bpj.2023.05.021
Publikováno v:
Proceedings of the nanoGe Fall Meeting 2021.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72c9d73812f5f0b5a5aa60a3ab14c904
https://doi.org/10.29363/nanoge.nfm.2021.214
https://doi.org/10.29363/nanoge.nfm.2021.214
Autor:
Marcelo F. Masman, Jeroen Drenth, Carlos Ramírez-Palacios, Siewert-Jan Marrink, Dick B. Janssen, Antonija Marjanovic, Marleen Otzen
Publikováno v:
Protein Engineering, Design & Selection, 34:gzab016
Protein Engineering, Design and Selection
Protein Engineering, Design and Selection
Diaminopimelate decarboxylases (DAPDCs) are highly selective enzymes that catalyze the common final step in different lysine biosynthetic pathways, i.e. the conversion of meso-diaminopimelate (DAP) to L-lysine. We examined the modification of the sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a7929bde320bdfb04bdd887a0235d1b
https://doi.org/10.1093/protein/gzab016
https://doi.org/10.1093/protein/gzab016
Autor:
Shengli, Zhang, Gang, Huang, Roderick Corstiaan Abraham, Versloot, Bart Marlon Herwig, Bruininks, Paulo Cesar Telles, de Souza, Siewert-Jan, Marrink, Giovanni, Maglia
Publikováno v:
Nature chemistry. 13(12)
The precise assembly and engineering of molecular machines capable of handling biomolecules play crucial roles in most single-molecule methods. In this work we use components from all three domains of life to fabricate an integrated multiprotein comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ea01682daed2045d33a16ef96b1b0816
https://pubmed.ncbi.nlm.nih.gov/35017735
https://pubmed.ncbi.nlm.nih.gov/35017735
Autor:
Gemma Moiset, Anna D Cirac, Marc C A Stuart, Siewert-Jan Marrink, Durba Sengupta, Bert Poolman
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61541 (2013)
Membrane active peptides can perturb the lipid bilayer in several ways, such as poration and fusion of the target cell membrane, and thereby efficiently kill bacterial cells. We probe here the mechanistic basis of membrane poration and fusion caused
Externí odkaz:
https://doaj.org/article/526c6692580c44daa7500e9bceca6803
Autor:
Herre Jelger Risselada, Giovanni Marelli, Marc Fuhrmans, Yuliya G. Smirnova, Helmut Grubmüller, Siewert Jan Marrink, Marcus Müller
Publikováno v:
PLoS ONE, Vol 8, Iss 10 (2013)
Externí odkaz:
https://doaj.org/article/7270da36c32945c28445da8061d8a1e7
Autor:
Giovanni Maglia, Gang Huang, Roderick Corstiaan Abraham Versloot, Shengli Zhang, Paulo C. T. Souza, Siewert-Jan Marrink, Bart Marlon Herwig
Transmembrane channels and pores have many biotechnological applications, notably in the single-molecule sequencing of DNA. Small synthetic nanopores have been designed using amphipathic peptides, or by assembling computationally designed transmembra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8c98e7f972fb3be05aaec406938a24a
https://doi.org/10.1101/2020.12.04.411884
https://doi.org/10.1101/2020.12.04.411884
Phosphosinositides (PIs) are lipid signaling molecules that operate by recruiting proteins to cellular membranes via PI recognition domains. Such domains are also used widely as fluorescence-coupled biosensors for cellular PIs. For PI(4,5)P2, the dom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38e8c2fb4cdfbd3e00d87667a89df15b
https://doi.org/10.1101/2020.09.23.309492
https://doi.org/10.1101/2020.09.23.309492
Publikováno v:
eLife, 9:e52012. ELIFE SCIENCES PUBLICATIONS LTD
eLife
eLife, Vol 9 (2020)
eLife
eLife, Vol 9 (2020)
The use of non-viral vectors for in vivo gene therapy could drastically increase safety, whilst reducing the cost of preparing the vectors. A promising approach to non-viral vectors makes use of DNA/cationic liposome complexes (lipoplexes) to deliver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8becc7104a8f6e0b6058c27fd267359e
https://research.rug.nl/en/publications/f6c01303-40d7-45da-bb91-718f7fb0a64d
https://research.rug.nl/en/publications/f6c01303-40d7-45da-bb91-718f7fb0a64d