Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Siew-Yen Chong"'
Autor:
Farooq Nasar, Ali Javadian, Amara Luckay, John H. Eldridge, Siew Yen Chong, Michael Hendry, Christopher L. Parks, Rashed Abdullah, Timothy J. Zamb, Margaret Lee, Peter B. Little, Susan E. Witko, Narender K. Kalyan, Roger E. Price, Becky Nowak, John W. Coleman, Shakuntala Megati, Stephen A. Udem, J. Erik Johnson, Andrew A. Lackner, Cheryl S. Kotash, Valerie Randolf, David K. Clarke, Michael A. Egan
Publikováno v:
Journal of Virology
In previous work, a prototypic recombinant vesicular stomatitis virus Indiana serotype (rVSIV) vector expressing simian immunodeficiency virus (SIV) gag and human immunodeficiency virus type 1 (HIV-1) env antigens protected nonhuman primates (NHPs) f
Autor:
Vidia Roopchard, Amjed Masood, Zimra R. Israel, Michele A. Kutzler, Shakuntala Megati, Maninder K. Sidhu, Dorys Garcia-Hand, Margherita Rosati, John H. Eldridge, Siew-Yen Chong, George N. Pavlakis, Michael A. Egan, David B. Weiner, Eva B. Schadeck, Jean D. Boyer, David C. Montefiori, Jorge Quiroz
Publikováno v:
Vaccine. 25:4967-4982
Plasmid-based IL-12 has been demonstrated to successfully enhance the immunogenicity of DNA vaccines, thus enabling a reduction of the amount of DNA required for immunization. IL-15 is thought to affect the maintenance and enhance effector function o
Autor:
Priscilla Piacente, Shakuntala Megati, Amjed Masood, Zimra R. Israel, John H. Eldridge, J. Erik Johnson, Dana L. Hasselschwert, Patricia A Reilly, John K. Rose, Kevin J Lopez, Preston A. Marx, David K. Clarke, David C. Montefiori, R. Michael Hendry, Stephen A. Udem, Mark G. Lewis, Eric M. Mishkin, Robert E Druilhet, Siew Yen Chong, Eva B. Schadeck, Paul W Barras, Nina F. Rose, Michael A. Egan
Publikováno v:
AIDS Research and Human Retroviruses. 20:989-1004
An experimental AIDS vaccine based on attenuated, recombinant vesicular stomatitis virus (rVSV), when administered by a combination of parenteral and mucosal routes, has proven effective at preventing AIDS in a rhesus macaque model (Rose NF, et al.:
Autor:
John H. Eldridge, Herman F. Staats, Priscilla Piacente, Ben-Jiang Ma, Zimra R. Israel, Barton F. Haynes, Siew Yen Chong, David C. Montefiori, Shakuntala Megati, Eva B. Schadeck, Michael Hagen, Michael A. Egan
Publikováno v:
Vaccine. 22:3774-3788
Cynomolgus macaques were immunized by either the intramuscular (i.m.) or intranasal (i.n.) route with a HIV-1 peptide-based immunogen (C4-V3 89.6P) alone, or formulated with novel adjuvants to evaluate the ability of the adjuvants to augment peptide-
Autor:
Nicholas M. Ponzio, Elizabeth Raveche, Yi-Chu Lin, Zenaida Garcia, Ming Zhang, Siew Yen Chong, Frederick D. Coffman
Publikováno v:
Cancer Immunology, Immunotherapy. 50:41-50
The transcription factor B-cell-specific activator protein (BSAP) plays an important role in B-cell development. We explored the involvement of BSAP in the growth regulation of malignant B-1 cells derived from the NZB murine model of human chronic ly
Autor:
Siew-Yen Chong, Fatah Kashanchi, Francisco Santiago, Masahiro Fujii, Fariba Mozafari, Carlos A. Molina, Nazli Azimi, Elizabeth Clark, Renaud Mahieux
Publikováno v:
Europe PubMed Central
Karolinska Institutet
Karolinska Institutet
Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent for adult T-cell leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis. Tax 1 is a 40-kDa phosphoprotein, predominantly localized in the nucleus of the
Autor:
Dorys Garcia-Hand, David B. Weiner, Shakuntala Megati, Maninder K. Sidhu, Amjed Masood, Margherita Rosati, Larry R. Smith, Siew-Yen Chong, Rong Xu, Sarah Cappello, Amara Luckay, Zimra R. Israel, Michael A. Egan, Solomon Sackitey, George N. Pavlakis, Barbara K. Felber, John H. Eldridge, Vidia Roopchand
Publikováno v:
Vaccine
Plasmid DNA (pDNA) vaccines are effective at eliciting immune responses in a wide variety of animal model systems, however, pDNA vaccines have generally been incapable of inducing robust immune responses in clinical trials. Therefore, to identify mea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703aaa15fe077667bce3fcb2ec1c6077
https://europepmc.org/articles/PMC7294827/
https://europepmc.org/articles/PMC7294827/
Autor:
John H. Eldridge, Michael A. Egan, Nicole B. Terio, Krista J. Melville, Deborah Long, Amara Luckay, Lee Anne C. Boutilier, Christopher L. Parks, Rashed Abdullah, Stephen A. Udem, Robert A. Lerch, Matthew B. Elliott, Tong Chen, Siew-Yen Chong, Gerald E. Hancock
Publikováno v:
Vaccine. 25(41)
Respiratory syncytial virus (RSV) is a major cause of acute respiratory tract disease in humans. Towards development of a prophylactic vaccine, we genetically engineered Venezuelan equine encephalitis virus (VEEV) replicons encoding the fusion (Fa) o
Autor:
Rashed Abdullah, Ralph P. Braun, Siew-Yen Chong, Maninder K. Sidhu, George N. Pavlakis, Barbara K. Felber, David C. Montefiori, Margherita Rosati, Dorys Garcia-Hand, Iacob Mathiesen, Zimra R. Israel, Shakuntala Megati, John H. Eldridge, Vidia Roopchand, Michael A. Egan, Rune Kjeken, Amara Luckay
Since human immunodeficiency virus (HIV)-specific cell-mediated immune (CMI) responses are critical in the early control and resolution of HIV infection and correlate with postchallenge outcomes in rhesus macaque challenge experiments, we sought to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2069b8bc8f187c0cfbfa6c9c2569ef6b
https://europepmc.org/articles/PMC1900241/
https://europepmc.org/articles/PMC1900241/
Autor:
John H. Eldridge, George N. Pavlakis, Shakuntala Megati, Vidia Roopchand, Priscilla Piacente, Barbara K. Felber, Jorge Quiroz, David B. Weiner, Zimra R. Israel, Sarah Cappello, Eva B. Schadeck, Dorys Garcia-Hand, Maninder K. Sidhu, Siew-Yen Chong, Jean D. Boyer, Michael A. Egan, Amjed Masood
Publikováno v:
Vaccine. 24(21)
An experimental pDNA vaccine adjuvant expressing IL-12 was evaluated for its ability to augment the humoral and cellular immune responses elicited by a SIVmac239 gag p39 expressing pDNA vaccine. To determine the effect of vaccine dose on the immune r