Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Siew-Bee Ng"'
Autor:
Elaine-Jinfeng Chin, Kuan-Chieh Ching, Zann Y. Tan, Mario Wibowo, Chung-Yan Leong, Lay-Kien Yang, Veronica W. P. Ng, Deborah C. S. Seow, Yoganathan Kanagasundaram, Siew-Bee Ng
Publikováno v:
Molecules, Vol 28, Iss 15, p 5832 (2023)
Natural products have long been used as a source of antimicrobial agents against various microorganisms. Actinobacteria are a group of bacteria best known to produce a wide variety of bioactive secondary metabolites, including many antimicrobial agen
Externí odkaz:
https://doaj.org/article/7e75b46c58f1406085f6df6a93617c5b
Autor:
Kuan-Chieh Ching, Elaine J. Chin, Mario Wibowo, Zann Y. Tan, Lay-Kien Yang, Deborah C. Seow, Chung-Yan Leong, Veronica W. Ng, Siew-Bee Ng, Yoganathan Kanagasundaram
Publikováno v:
Molecules, Vol 28, Iss 1, p 101 (2022)
Thiopeptides are macrocyclic natural products with potent bioactivity. Nine new natural thiopeptides (1–9) were obtained from a Nonomuraea jiangxiensis isolated from a terrestrial soil sample collected in Singapore. Even though some of these compou
Externí odkaz:
https://doaj.org/article/e069023bf6a241dba0186e3be930deea
Autor:
Kuan-Chieh Ching, Elaine J. Chin, Mario Wibowo, Zann Y. Tan, Lay-Kien Yang, Deborah C. Seow, Chung-Yan Leong, Veronica W. Ng, Siew-Bee Ng, Yoganathan Kanagasundaram
Publikováno v:
Molecules, Vol 27, Iss 23, p 8196 (2022)
Large scale cultivation and chemical investigation of an extract obtained from Actimonadura sp. resulted in the identification of six previously undescribed spirotetronates (pyrrolosporin B and decatromicins C–G; 7–12), along with six known conge
Externí odkaz:
https://doaj.org/article/5a75cf5e4bda47d5a23d26f56116776e
Autor:
Falicia Goh, Mingzi M. Zhang, Tian Ru Lim, Kia Ngee Low, Choy Eng Nge, Elena Heng, Wan Lin Yeo, Fernanda L. Sirota, Sharon Crasta, Zann Tan, Veronica Ng, Chung Yan Leong, Huibin Zhang, Alexander Lezhava, Swaine L. Chen, Shawn S. Hoon, Frank Eisenhaber, Birgit Eisenhaber, Yoganathan Kanagasundaram, Fong T. Wong, Siew Bee Ng
Publikováno v:
Microbial Cell Factories, Vol 19, Iss 1, Pp 1-13 (2020)
Abstract Notonesomycin A is a 32-membered bioactive glycosylated macrolactone known to be produced by Streptomyces aminophilus subsp. notonesogenes 647-AV1 and S. aminophilus DSM 40186. In a high throughput antifungal screening campaign, we identifie
Externí odkaz:
https://doaj.org/article/ec0148909bdf449eae2f3e74c507b601
Autor:
Elena Heng, Lee Ling Tan, Dillon W.P. Tay, Yee Hwee Lim, Lay-Kien Yang, Deborah C.S. Seow, Chung Yan Leong, Veronica Ng, Siew Bee Ng, Yoganathan Kanagasundaram, Fong Tian Wong, Lokanand Koduru
Publikováno v:
Synth Syst Biotechnol
With the advent of rapid automated in silico identification of biosynthetic gene clusters (BGCs), genomics presents vast opportunities to accelerate natural product (NP) discovery. However, prolific NP producers, Streptomyces, are exceptionally GC-ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6acd0ff446f74e7f14e3367a26f03e71
https://doi.org/10.1016/j.synbio.2023.03.001
https://doi.org/10.1016/j.synbio.2023.03.001
Autor:
Swati Sinha, Choy-Eng Nge, Chung Yan Leong, Veronica Ng, Sharon Crasta, Mohammad Alfatah, Falicia Goh, Kia-Ngee Low, Huibin Zhang, Prakash Arumugam, Alexander Lezhava, Swaine L. Chen, Yoganathan Kanagasundaram, Siew Bee Ng, Frank Eisenhaber, Birgit Eisenhaber
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-18 (2019)
Abstract Background Phomafungin is a recently reported broad spectrum antifungal compound but its biosynthetic pathway is unknown. We combed publicly available Phoma genomes but failed to find any putative biosynthetic gene cluster that could account
Externí odkaz:
https://doaj.org/article/7802baec2e984d30bb9af5de5f8a5b7c
Autor:
Fong Tian Wong, Elena Heng, Yi Wee Lim, Chung Yan Leong, Veronica W. P. Ng, Siew Bee Ng, Yee Hwee Lim
Publikováno v:
Microbial Cell Factories. 22
Background Nature has provided unique molecular scaffolds for applications including therapeutics, agriculture, and food. Due to differences in ecological environments and laboratory conditions, engineering is often necessary to uncover and utilize t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a5d586eb86406149342c1b6f3ad1a40
https://doi.org/10.1186/s12934-023-02092-4
https://doi.org/10.1186/s12934-023-02092-4
Publikováno v:
Critical Reviews in Food Science and Nutrition
Critical Reviews in Food Science and Nutrition (2023)
Critical Reviews in Food Science and Nutrition (2023)
Multiple beneficial effects have been attributed to green tea catechins (GTCs). However, the bioavailability of GTCs is generally low, with only a small portion directly absorbed in the small intestine. The majority of ingested GTCs reaches the large
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ee7ce2ec979e0b5ce0b0433e7a48d5
https://research.wur.nl/en/publications/gut-microbiota-mediated-metabolism-of-green-tea-catechins-and-the
https://research.wur.nl/en/publications/gut-microbiota-mediated-metabolism-of-green-tea-catechins-and-the
Autor:
Madhaiyan Munusamy, Kenneth Tan, Choy Eng Nge, Martin Muthee Gakuubi, Sharon Crasta, Yoganathan Kanagasundaram, Siew Bee Ng
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 2; Pages: 1033
Adaptation to a wide variety of habitats allows fungi to develop unique abilities to produce diverse secondary metabolites with diverse bioactivities. In this study, 30 Ascomycetes fungi isolated from St. John's Island, Singapore were investigated fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b3eaf5d2d8fac9ef51a19d2b2e1ec44
https://hdl.handle.net/10356/169563
https://hdl.handle.net/10356/169563
Autor:
Elena Heng, Lee Ling Tan, Dillon W. P. Tay, Yee Hwee Lim, Lay-Kien Yang, Deborah C.S. Seow, Chung Yan Leong, Veronica Ng, Siew Bee Ng, Yoganathan Kanagasundaram, Fong Tian Wong, Lokanand Koduru
With the advent of rapid automatedin silicoidentification of biosynthetic gene clusters (BGCs), genomics presents vast opportunities to accelerate natural product (NP) discovery. However, prolific NP producers,Streptomyces, are exceptionally GC-rich
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62d53e82e79e276898728c6ea9f03c2b
https://doi.org/10.1101/2022.12.05.519232
https://doi.org/10.1101/2022.12.05.519232