Zobrazeno 1 - 10
of 566
pro vyhledávání: '"Siew C., Ng"'
Autor:
Wenye Xu, Yuchen Zhang, Dongjiao Chen, Dan Huang, Yang Zhao, Wei Hu, Ling Lin, Yingzhi Liu, Shilan Wang, Judeng Zeng, Chuan Xie, Hung Chan, Qing Li, Huarong Chen, Xiaodong Liu, Sunny H. Wong, Jun Yu, Francis K. L. Chan, Matthew T. V. Chan, Siew C. Ng, William K. K. Wu, Lin Zhang
Publikováno v:
Gut Pathogens, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background Fusobacterium nucleatum (F. nucleatum) is one of the key tumorigenic bacteria in colorectal cancer (CRC), yet how F. nucleatum is involved in colorectal cancer carcinogenesis remains unknown. Results In the present study, we carri
Externí odkaz:
https://doaj.org/article/b61bd6e59fff42d584fb0a93eec26fe1
Autor:
Yating Wan, Oscar W.H. Wong, Hein M Tun, Qi Su, Zhilu Xu, Whitney Tang, Suk Ling Ma, Sandra Chan, Francis K L Chan, Siew C Ng
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Accumulating evidence suggests that gut microbiota alterations influence brain function and could serve as diagnostic biomarkers and therapeutic targets. The potential of using fecal microbiota signatures to aid autism spectrum disorder (ASD) detecti
Externí odkaz:
https://doaj.org/article/2fcb62ce83bd490dbc63e8a1c6fc52ad
Autor:
Hui Zhan, Yating Wan, Yang Sun, Zhilu Xu, Fen Zhang, Keli Yang, Wenyi Zhu, Chun Pan Cheung, Whitney Tang, Enders Kw Ng, Simon Kh Wong, Yun Kit Yeoh, Francis Kl Chan, Yinglei Miao, Tao Zuo, Zhong Zeng, Siew C Ng
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
The gut fungi play important roles in human health and are involved in energy metabolism. This study aimed to examine gut mycobiome composition in obese subjects in two geographically different regions in China and to identify specific gut fungi asso
Externí odkaz:
https://doaj.org/article/699e728ce2fb4712bb3676916ad89e98
Autor:
Ye Peng, Hein M Tun, Siew C Ng, Hogan Kok-Fung Wai, Xi Zhang, Jaclyn Parks, Catherine J Field, Piush Mandhane, Theo J Moraes, Elinor Simons, Stuart E Turvey, Padmaja Subbarao, Jeffrey R Brook, Tim K Takaro, James A Scott, Francis KL Chan, Anita L Kozyrskyj
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTChildhood obesity is linked to maternal smoking during pregnancy. Gut microbiota may partially mediate this association and could be potential targets for intervention; however, its role is understudied. We included 1,592 infants from the Can
Externí odkaz:
https://doaj.org/article/b77c695a37b84ae1bdc381cb24872a84
Autor:
Shilin Zhao, Kris Y. W. Lok, Zhen Y. Sin, Ye Peng, Heidi S. L. Fan, Nitya Nagesh, Martha S. L. Choi, Jojo Y. Y. Kwok, Edmond P. H. Choi, Xi Zhang, Hogan Kok-Fung Wai, Leo C. H. Tsang, Samuel S. M. Cheng, Matthew K. L. Wong, Jie Zhu, Chris K. P. Mok, Siew C. Ng, Francis K. L. Chan, Malik Peiris, Leo L. M. Poon, Hein M. Tun
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-11 (2023)
Abstract Newborns can acquire immunological protection to SARS-CoV-2 through vaccine-conferred antibodies in human breast milk. However, there are some concerns around lactating mothers with regards to potential short- and long-term adverse events an
Externí odkaz:
https://doaj.org/article/97c98fea7c374c10952279eef846a51e
Autor:
Ye Peng, Lin Zhang, Chris K. P. Mok, Jessica Y. L. Ching, Shilin Zhao, Matthew K. L. Wong, Jie Zhu, Chunke Chen, Shilan Wang, Shuai Yan, Biyan Qin, Yingzhi Liu, Xi Zhang, Chun Pun Cheung, Pui Kuan Cheong, Ka Long Ip, Adrian C. H. Fung, Kenneth K. Y. Wong, David S. C. Hui, Francis K. L. Chan, Siew C. Ng, Hein M. Tun
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-11 (2023)
Abstract The role of gut microbiota in modulating the durability of COVID-19 vaccine immunity is yet to be characterised. In this cohort study, we collected blood and stool samples of 121 BNT162b2 and 40 CoronaVac vaccinees at baseline, 1 month, and
Externí odkaz:
https://doaj.org/article/585d846b6ce94040a79626ac1d00681e
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTIrritable bowel syndrome (IBS) is a heterogeneous condition with multifactorial pathogenesis. We studied deeply phenotyped individuals with microbiota sequencing enrolled in the American Gut Project. The IBS subjects were matched by age, gend
Externí odkaz:
https://doaj.org/article/59a729d76ae64f60861e05c63044edaa
Autor:
Joyce W. Y. Mak, Yang Sun, Julajak Limsrivilai, Murdani Abdullah, Jamilya Kaibullayeva, Domingo Balderramo, Beatriz Iade Vergara, Mukesh Sharma Paudel, Rupa Banerjee, Ida Hilmi, Raja Affendi Raja Ali, Shu Chen Wei, Ka Kei Ng, Mansour Altuwaijri, Paul Kelly, Jesus K. Yamamoto-Furusho, Paulo Gustavo Kotze, Vineet Ahuja, Vui Heng Chong, Hang Viet Dao, Yvonne Abbey, Jessica Y. L. Ching, Agnes Ho, Alicia K. W. Chan, Charles N. Bernstein, Richard B. Gearry, Maria Abreu, David T. Rubin, Iris Dotan, Lindsay Hracs, Gilaad G. Kaplan, Siew C. Ng, On behalf of the GIVES-21 Consortium
Publikováno v:
BMC Medical Research Methodology, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Background There is a rapid increase in the incidence of inflammatory bowel diseases (IBD) in newly industrialized countries, yet epidemiological data is incomplete. We herein report the methodology adopted to study the incidence of IBD in n
Externí odkaz:
https://doaj.org/article/e7a494e9d6704e8db216b31d6b3d2873
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
IntroductionEmerging preclinical and clinical studies suggest that altered gut microbiome composition and functions are associated with coronavirus 2019 (COVID- 19) severity and its long-term complications. We hypothesize that COVID-19 outcome is ass
Externí odkaz:
https://doaj.org/article/38fd4c22b4c940dcb2027f6b0199e443
Autor:
Qi Su, Qin Liu, Raphaela Iris Lau, Jingwan Zhang, Zhilu Xu, Yun Kit Yeoh, Thomas W. H. Leung, Whitney Tang, Lin Zhang, Jessie Q. Y. Liang, Yuk Kam Yau, Jiaying Zheng, Chengyu Liu, Mengjing Zhang, Chun Pan Cheung, Jessica Y. L. Ching, Hein M. Tun, Jun Yu, Francis K. L. Chan, Siew C. Ng
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
Here, using fecal metagenomics data of 2,320 individuals, the authors develop a microbiome-based machine learning approach showing high accuracy for multi-class disease diagnosis, highlighting its potential application in improving noninvasive diagno
Externí odkaz:
https://doaj.org/article/4d13f20fc0364cfc832e975f3b7201d3