Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Sietse M. Aukema"'
Autor:
Cristina López, Kortine Kleinheinz, Sietse M. Aukema, Marius Rohde, Stephan H. Bernhart, Daniel Hübschmann, Rabea Wagener, Umut H. Toprak, Francesco Raimondi, Markus Kreuz, Sebastian M. Waszak, Zhiqin Huang, Lina Sieverling, Nagarajan Paramasivam, Julian Seufert, Stephanie Sungalee, Robert B. Russell, Julia Bausinger, Helene Kretzmer, Ole Ammerpohl, Anke K. Bergmann, Hans Binder, Arndt Borkhardt, Benedikt Brors, Alexander Claviez, Gero Doose, Lars Feuerbach, Andrea Haake, Martin-Leo Hansmann, Jessica Hoell, Michael Hummel, Jan O. Korbel, Chris Lawerenz, Dido Lenze, Bernhard Radlwimmer, Julia Richter, Philip Rosenstiel, Andreas Rosenwald, Markus B. Schilhabel, Harald Stein, Stephan Stilgenbauer, Peter F. Stadler, Monika Szczepanowski, Marc A. Weniger, Marc Zapatka, Roland Eils, Peter Lichter, Markus Loeffler, Peter Möller, Lorenz Trümper, Wolfram Klapper, ICGC MMML-Seq Consortium, Steve Hoffmann, Ralf Küppers, Birgit Burkhardt, Matthias Schlesner, Reiner Siebert
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Burkitt lymphoma (BL) is the most common pediatric B-cell lymphoma. Here, within the International Cancer Genome Consortium, the authors performed whole genome and transcriptome sequencing of 39 sporadic BL, describing the landscape of mutations, str
Externí odkaz:
https://doaj.org/article/0f2708368b2a4696b47220ee30732ce8
Autor:
Ingram Iaccarino, Lamis Afify, Sietse M. Aukema, Katharina Reddemann, Philipp Schütt, Martin Flür, Wolfram Klapper
Publikováno v:
Haematologica, Vol 103, Iss 9 (2018)
Externí odkaz:
https://doaj.org/article/b27f416bc9264e03ab08d9fc1bbeadfc
Autor:
Sietse M. Aukema, Markus Kreuz, Christian W Kohler, Maciej Rosolowski, Dirk Hasenclever, Michael Hummel, Ralf Küppers, Dido Lenze, German Ott, Christiane Pott, Julia Richter, Andreas Rosenwald, Monika Szczepanowski, Carsten Schwaenen, Harald Stein, Heiko Trautmann, Swen Wessendorf, Lorenz Trümper, Markus Loeffler, Rainer Spang, Philip M. Kluin, Wolfram Klapper, Reiner Siebert
Publikováno v:
Haematologica, Vol 99, Iss 4 (2014)
Chromosomal translocations affecting the MYC oncogene are the biological hallmark of Burkitt lymphomas but also occur in a subset of other mature B-cell lymphomas. If accompanied by a chromosomal break targeting the BCL2 and/or BCL6 oncogene these MY
Externí odkaz:
https://doaj.org/article/8ade27f09fd947668de3641b424b15ba
Autor:
Lucinda Sanders, Sandrine Jayne, Ben Kennedy, Fiona Miall, Sietse M. Aukema, Reiner Siebert, Simon D. Wagner, Martin J. S. Dyer
Publikováno v:
Case Reports in Hematology, Vol 2014 (2014)
The WHO classification of lymphomas allows for a group of diseases that have features intermediate between those of Burkitt lymphoma and diffuse large B-cell lymphoma. These are a diverse group of diseases whose genetics and clinical course are yet t
Externí odkaz:
https://doaj.org/article/95fbee634a84471c83274a174f5a3d10
Autor:
Sietse M. Aukema, Selina Glaser, Mari F. C. M. van den Hout, Sonja Dahlum, Marinus J. Blok, Morten Hillmer, Julia Kolarova, Raf Sciot, Dina A. Schott, Reiner Siebert, Constance T. R. M. Stumpel
Publikováno v:
Familial Cancer. 22:103-118
Kabuki syndrome is a well-recognized syndrome characterized by facial dysmorphism and developmental delay/intellectual disability and in the majority of patients a germline variant in KMT2D is found. As somatic KMT2D variants can be found in 5–10%
Autor:
Markus Schillhabel, Alfonso Valencia, Anke K. Bergmann, Eva Reisinger, Hendrik G. Stunnenberg, Marc A. Weniger, Stephan H. Bernhart, Christoph Borst, Volker Hovestadt, Andrea Haake, Naveed Ishaque, Markus Loeffler, Christina Jäger-Schmidt, Matthias Bieg, Arndt Borkhardt, Gero Doose, Hans Binder, Jules Kerssemakers, Bernhard Radlwimmer, Markus Kreuz, Kortine Kleinheinz, Stephan Stilgenbauer, Andreas Rosenwald, Alexander Claviez, Benedikt Brors, Michael Hummel, Matthias Schlesner, Bingding Huang, Reiner Siebert, Peter Lichter, Chris Lawerenz, José I. Martín-Subero, Cristina López, Marc Zapatka, Monika Szczepanowski, Ole Ammerpohl, Umut H. Toprak, Peter Möller, Nagarajan Paramasivam, Wolfram Klapper, Philip Rosenstiel, Martin-Leo Hansmann, Dieter Kube, Helene Kretzmer, Ralf Küppers, Julia Richter, Steve Hoffmann, Sietse M. Aukema, Siegfried Haas, Jan O. Korbel, Dennis Karsch, Renée Beekman, Enrique Carrillo de Santa Pau, Roland Eils, Daniel Rico, Philipp Bruns, Jessica I. Hoell, Stephanie Sungalee, Dido Lenze, Sebastian M. Waszak, Gregor Warsow, Rabea Wagener, Joost H.A. Martens, German Ott, Lorenz Trümper, Peter F. Stadler, Daniel Hübschmann
Publikováno v:
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Leukemia
Leukemia : the Journal of Normal and Malignant Hemopoiese ; Official Journal of the Leukemia Research Fund U.K.
Universitat Politècnica de Catalunya (UPC)
Leukemia
Leukemia : the Journal of Normal and Malignant Hemopoiese ; Official Journal of the Leukemia Research Fund U.K.
B cells have the unique property to somatically alter their immunoglobulin (IG) genes by V(D)J recombination, somatic hypermutation (SHM) and class-switch recombination (CSR). Aberrant targeting of these mechanisms is implicated in lymphomagenesis, b
Autor:
Leonard P. Morssink, Elianne J.L.E. Vrijlandt, Michiel J. Santing, Ryan E. Accord, Wilhelmina S. Kerstjens-Frederikse, Karianne E. Kraft, Gerdien A. ten Brinke, Esther Streefland, Sietse M. Aukema, Wim Timens, Yvonne J. Vos, Cleo C. van Diemen, Christian V. Hulzebos
Publikováno v:
American Journal of Medical Genetics. Part A, 182(9), 2152-2160. Wiley
The etiology of nonimmune hydrops fetalis is extensive and includes genetic disorders. We describe a term-born female neonate with late onset extensive nonimmune hydrops, that is, polyhydramnios, edema, and congenital bilateral chylothorax. This newb
Autor:
Sietse M. Aukema, Christa M. de Geus, Simon G. F. Robben, Kim J. A. F. van Kaam, Heleen M. Staal, Adhiambo M. Witlox, Nicole A. J. de la Haye, Merel Klaassens, Audrey Coumans, Alexander P. A. Stegmann, Dror Paley, Constance T. R. M. Stumpel
Publikováno v:
American Journal of Medical Genetics Part A, 188(3), 1000-1004. Wiley
American Journal of Medical Genetics, Part A, 188(3), 1000-1004. Wiley
American Journal of Medical Genetics, Part A, 188(3), 1000-1004. Wiley
Autor:
Kathrin Oehl-Huber, Sandrine Jayne, Julia Bausinger, Anneke G. Bosga-Bouwer, Ilske Oschlies, Wolfram Klapper, Sietse M. Aukema, Rabea Wagener, Andreas Rosenwald, Eva Hoster, Wilfried Belder, Markus Kreuz, Philip M. Kluin, Iris Bittmann, Reiner Siebert, Giorgio A. Croci, Eva Maria Murga Penas, Inga Nagel, Martin J. S. Dyer, Mels Hoogendoorn, German Ott, Eva van den Berg, Susanne Bens
Publikováno v:
Virchows Archiv, 479, 133-145. SPRINGER
Chromosomal breakpoints involving the MYC gene locus, frequently referred to as MYC rearrangements (MYC - R+), are a diagnostic hallmark of Burkitt lymphoma and recurrent in many other subtypes of B-cell lymphomas including follicular lymphoma, diffu
Autor:
Marie-Hélène Delfau-Larue, Grzegorz Rymkiewicz, Eva Hoster, Sylvia Hartmann, Andreas Rosenwald, Wolfram Klapper, Sietse M. Aukema, Christoph Thorns, Olivier Hermine, Danielle Canoni, Hanneke C. Kluin-Nelemans, Martin Dreyling
Publikováno v:
Blood, 131(4), 417-420. AMER SOC HEMATOLOGY
Currently, prediction of time to treatment failure (TTF) and overall survival (OS) in mantle cell lymphoma (MCL) is based on the clinical factors included in the Mantle Cell Lymphoma International Prognostic Index (MIPI), and proliferation is assesse