Výsledky vyhledávání - "Sietse J. Luk"

Akademický článek

Imaging mass cytometry reveals the prominent role of myeloid cells at the maternal-fetal interface

Autor: Juliette Krop, Anita van der Zwan, Marieke E. Ijsselsteijn, Hanneke Kapsenberg, Sietse J. Luk, Sanne H. Hendriks, Carin van der Keur, Lotte J. Verleng, Antonis Somarakis, Lotte van der Meeren, Geert Haasnoot, Manon Bos, Noel F.C.C. de Miranda, Susana M. Chuva de Sousa Lopes, Marie-Louise P. van der Hoorn, Frits Koning, Frans H.J. Claas, Sebastiaan Heidt, Michael Eikmans

Publikováno v: iScience, Vol 25, Iss 7, Pp 104648- (2022)

Summary: Although the immunological complexity of the maternal-fetal interface is well appreciated, the actual interaction of maternal immune cells and fetal trophoblasts is insufficiently understood. To comprehend the composition and spatial orienta

Externí odkaz: https://doaj.org/article/2f915b7656e34a9eb9b7e0a3202223f6

Zobrazit plný text záznamu

Akademický článek

PRAME and HLA Class I expression patterns make synovial sarcoma a suitable target for PRAME specific T-cell receptor gene therapy

Autor: Sietse J Luk, Dirk M van der Steen, Renate S Hagedoorn, Ekaterina S Jordanova, Marco W Schilham, Judith VMG Bovée, Arjen HG Cleven, JH Frederik Falkenburg, Karoly Szuhai, Mirjam HM Heemskerk

Publikováno v: OncoImmunology, Vol 7, Iss 12 (2018)

Synovial sarcoma expresses multiple cancer testis antigens that could potentially be targeted by T-cell receptor (TCR) gene therapy. In this study we investigated whether PRAME-TCR-gene therapy could be an effective treatment for synovial sarcoma by

Externí odkaz: https://doaj.org/article/65c69a122ffc47aebe923affccb2dc4b

Zobrazit plný text záznamu

Visual cohort comparison for spatial single-cell omics-data

Autor: Boyd Kenkhuis, Marieke E. Ijsselsteijn, Thomas Höllt, Noel F C C de Miranda, Boudewijn P. F. Lelieveldt, Antonios Somarakis, Sietse J. Luk

Publikováno v: IEEE Transactions on Visualization and Computer Graphics, 27(2), 733-743. IEEE COMPUTER SOC
IEEE Transactions on Visualization and Computer Graphics
IEEE Transactions on Visualization and Computer Graphics, 27(2)

Spatially-resolved omics-data enable researchers to precisely distinguish cell types in tissue and explore their spatial interactions, enabling deep understanding of tissue functionality. To understand what causes or deteriorates a disease and identi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83dedd042ee6a560110f8f0057e9d9fc
http://hdl.handle.net/1887/3264160

Zobrazit plný text záznamu

Visualizing the Prevalence and Interactions of Maternal Immune Cells and Fetal Trophoblasts Using Imaging Mass Cytometry: The Prominence of Myeloid Cells

Autor: Juliette Krop, Anita van der Zwan, Marieke E. Ijsselsteijn, Hanneke Kapsenberg, Sietse J. Luk, Sanne H. Hendriks, Carin van der Keur, Lotte J. Verleng, Antonis Somarakis, Lotte van der Meeren, Geert W. Haasnoot, Manon Bos, Noel F. C. C. de Miranda, Susana M. Chuva de Sousa Lopes, Marie-Louise P. van der Hoorn, Frits Koning, Frans HJ Claas, Sebastiaan Heidt, Michael Eikmans

Publikováno v: SSRN Electronic Journal.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e66802499b86876c4e83a3c0f41a10a8
https://doi.org/10.2139/ssrn.3921277

Zobrazit plný text záznamu

PRAME as a Potential Target for Immunotherapy in Metastatic Uveal Melanoma

Autor: Pieter A. van der Velden, Martine J. Jager, Daniëlle Krijgsman, Dirk M. van der Steen, Renate S. Hagedoorn, Gregorius P M Luyten, Mehmet Dogrusöz, J. William Harbour, Mirjam H.M. Heemskerk, Gülçin Gezgin, Jinfeng Cao, Matthew G. Field, Karoly Szuhai, Ekaterina S. Jordanova, Sietse J. Luk

Publikováno v: JAMA Ophthalmology, 135(6)
Gezgin, G, Luk, S J, Cao, J, Dogrusoz, M, van der Steen, D M, Hagedoorn, R S, Krijgsman, D, van der Velden, P A, Field, M G, Luyten, G P M, Szuhai, K, Harbour, J W, Jordanova, E S, Heemskerk, M H M & Jager, M J 2017, ' PRAME as a Potential Target for Immunotherapy in Metastatic Uveal Melanoma ', Jama ophthalmology, vol. 135, no. 6, pp. 541-549 . https://doi.org/10.1001/jamaophthalmol.2017.0729
Jama ophthalmology, 135(6), 541-549. American Medical Association

Importance Uveal melanoma (UM) is an intraocular primary malignant neoplasm that often gives rise to metastatic disease for which there are no effective therapies. A substantial proportion of UMs express the cancer-testis antigen PRAME (preferentiall

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::754a5bd9ff2e5f5504868a8ece38d5a6
https://doi.org/10.1001/jamaophthalmol.2017.0729

Zobrazit plný text záznamu

PRAME and HLA Class I expression patterns make synovial sarcoma a suitable target for PRAME specific T-cell receptor gene therapy

Autor: Judith V.M.G. Bovée, Mirjam H.M. Heemskerk, Marco W. Schilham, Ekaterina S. Jordanova, J.H. Frederik Falkenburg, Arjen H.G. Cleven, Karoly Szuhai, Dirk M. van der Steen, Renate S. Hagedoorn, Sietse J. Luk

Publikováno v: OncoImmunology, 7(12). Landes Bioscience
Luk, S J, Steen, D M V D, Hagedoorn, R S, Jordanova, E S, Schilham, M W, Bovée, J V MG, Cleven, A H G, Falkenburg, J H F, Szuhai, K & Heemskerk, M H M 2018, ' PRAME and HLA Class I expression patterns make synovial sarcoma a suitable target for PRAME specific T-cell receptor gene therapy ', OncoImmunology, vol. 7, no. 12 . https://doi.org/10.1080/2162402X.2018.1507600
Oncoimmunology
OncoImmunology, Vol 7, Iss 12 (2018)
OncoImmunology, 7(12)
OncoImmunology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62d59316e6a2ddefbdf086681278966c
https://research.vumc.nl/en/publications/d441dc61-b512-4089-9b4a-e053c6406d6c

Zobrazit plný text záznamu

NFATC2 (nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2)

Autor: Pcw Hogendoorn, Karoly Szuhai, Sietse J Luk

Publikováno v: Atlas of Genetics and Cytogenetics in Oncology and Haematology.

Review on NFATC2 (nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2), with data on DNA, on the protein encoded, and where the gene is implicated.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ead8d9505aa78aca0c3a2aae05c80ff7
https://doi.org/10.4267/2042/48470

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání