Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Sierra A. Jaramillo"'
Autor:
Savanna N. Weninger, Chloe Herman, Rachel K. Meyer, Eve T. Beauchemin, Archana Kangath, Adelina I. Lane, Taylor M. Martinez, Tahia Hasneen, Sierra A. Jaramillo, Jason Lindsey, Gayatri Vedantam, Haijiang Cai, Emily K. Cope, J. Gregory Caporaso, Frank A. Duca
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-21 (2023)
Abstract Background Upper small intestinal dietary lipids activate a gut-brain axis regulating energy homeostasis. The prebiotic, oligofructose (OFS) improves body weight and adiposity during metabolic dysregulation but the exact mechanisms remain un
Externí odkaz:
https://doaj.org/article/b5f6a5e76ea84f92a3f3d295a21f0069
Autor:
Wenjuan Dong, Jing Wang, Lei Tian, Jianying Zhang, Erik W. Settles, Chao Qin, Daniel R. Steinken-Kollath, Ashley N. Itogawa, Kimberly R. Celona, Jinhee Yi, Mitchell Bryant, Heather Mead, Sierra A. Jaramillo, Hongjia Lu, Aimin Li, Ross E. Zumwalt, Sanjeet Dadwal, Pinghui Feng, Weiming Yuan, Sean P. J. Whelan, Paul S. Keim, Bridget Marie Barker, Michael A. Caligiuri, Jianhua Yu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
The serine protease factor Xa (FXa) is upregulated in COVID-19 patients and functions in the coagulation pathway. Here, Dong et al characterise the basis of its antiviral activity in the context of SARS-CoV-2 pandemic variants.
Externí odkaz:
https://doaj.org/article/b9e60e8540004b07b41e6a1c7eaa4a58
Autor:
Katherine E. Zarn, Sierra A. Jaramillo, Anthony R. Zapata, Nathan E. Stone, Ashley N. Jones, Haley E. Nunnally, Erik W. Settles, Ken Ng, Paul S. Keim, Steen Knudsen, Patricia M. Nuijten, Aloys S. L. Tijsma, Christopher T. French
Publikováno v:
PLoS ONE, Vol 17, Iss 9 (2022)
We recently published a preliminary assessment of the activity of a poly (ADP-ribose) polymerase (PARP) inhibitor, stenoparib, also known as 2X-121, which inhibits viral replication by affecting pathways of the host. Here we show that stenoparib effe
Externí odkaz:
https://doaj.org/article/7f790e1a8dfb46e3a3c0fd70f52ee73b
Autor:
Nathan E. Stone, Sierra A. Jaramillo, Ashley N. Jones, Adam J. Vazquez, Madison Martz, Lora M. Versluis, Marlee O. Raniere, Haley E. Nunnally, Katherine E. Zarn, Roxanne Nottingham, Ken R. Ng, Jason W. Sahl, David M. Wagner, Steen Knudsen, Erik W. Settles, Paul Keim, Christopher T. French
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
New therapeutics are urgently needed in the fight against COVID-19. Repurposing drugs that are either already approved for human use or are in advanced stages of the approval process can facilitate more rapid advances toward this goal.
Externí odkaz:
https://doaj.org/article/620d821873f544a29175de77273152c9
Akademický článek
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Autor:
Emily M. Borsom, Kathryn Conn, Christopher R. Keefe, Chloe Herman, Gabrielle M. Orsini, Allyson H. Hirsch, Melanie Palma Avila, George Testo, Sierra A. Jaramillo, Evan Bolyen, Keehoon Lee, J. Gregory Caporaso, Emily Cope
Publikováno v:
Microbiology Spectrum. 11
The gut microbiota-brain axis is suspected to contribute to the development of Alzheimer’s Disease (AD), a neurodegenerative disease characterized by amyloid-β plaque deposition, neurofibrillary tangles, and neuroinflammation. To evaluate the role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb854d2929bc10277a5a3b69a1265c2e
https://doi.org/10.1128/spectrum.03458-22
https://doi.org/10.1128/spectrum.03458-22
Autor:
Emily M Borsom, Christopher R Keefe, Allyson H Hirsch, Kathryn A Conn, Gabrielle M Orsini, Sierra A Jaramillo, Evan K Bolyen, Matthew R Dillon, Keehoon Lee, J. Gregory Caporaso, Emily K Cope
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48d07d22898688cbd34cc8963d238ac8
https://doi.org/10.1002/alz.066307
https://doi.org/10.1002/alz.066307
Autor:
Emily M Borsom, Kathryn A Conn, Christopher R Keefe, Allyson H Hirsch, Gabrielle M Orsini, Sierra A Jaramillo, George Testo, Melanie Palma Avila, Evan K Bolyen, Matthew R Dillon, Keehoon Lee, J. Gregory Caporaso, Emily K Cope
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e0f63dc60964426694148242b095c10
https://doi.org/10.1002/alz.066299
https://doi.org/10.1002/alz.066299
Autor:
Haley E Nunnally, Ashley N Jones, Ken Ng, Nathan E. Stone, Erik W. Settles, Steen Knudsen, Katherine E. Zarn, Anthony R Zapata, Aloys Si Tijsma, Paul Keim, Sierra A. Jaramillo, Christopher T French, Patricia M Nuijten
We recently published a preliminary assessment of the activity of a poly (ADP-ribose) polymerase (PARP) inhibitor, stenoparib, also known as 2X-121, which inhibits viral replication by affecting pathways of the host. Stenoparib is an inhibitor of mam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8321e34dca9c9f751045dd63713068cf
https://doi.org/10.1101/2021.11.03.467186
https://doi.org/10.1101/2021.11.03.467186
Autor:
Jordi B. Torrelles, Bridget M. Barker, Wenjuan Dong, Jun-Gyu Park, Nathan E. Stone, Jianying Zhang, Aimin Li, Michael A. Caligiuri, Martha Milanes-Yearsley, Li-Shu Wang, Lei Tian, Paul Keim, Sierra A. Jaramillo, Luis Martinez-Sobrido, Juan Ignacio García, Vanessa K Coyne, Heather L. Mead, Jianhua Yu, Tasha Barr, Daniel S Kollath, Ashley N Jones
Publikováno v:
Journal of Virology
A comprehensive analysis and characterization of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection model that mimics non-severe and severe coronavirus disease 2019 (COVID-19) in humans is warranted for understating the virus an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f8a3ab93dcbb987847846b45c0d8c0f
https://pubmed.ncbi.nlm.nih.gov/34668775
https://pubmed.ncbi.nlm.nih.gov/34668775