Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Siegmund G. Wanner"'
Autor:
Stanislav Berjukov, Irene G. Huber, Steffen Hering, Jörg Striessnig, Géza Tóth, Philipp Eller, S. David Kimball, Hans-Günther Knaus, Siegmund G. Wanner
Publikováno v:
British Journal of Pharmacology. 130:669-677
Mibefradil is a novel Ca2+ antagonist which blocks both high-voltage activated and low voltage-activated Ca2+ channels. Although L-type Ca2+ channel block was demonstrated in functional experiments its molecular interaction with the channel has not y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fb3fdd5d7cd923e39f55276c9854be0
https://doi.org/10.1038/sj.bjp.0703352
https://doi.org/10.1038/sj.bjp.0703352
Autor:
Alexandra Koschak, Hans-Günther Knaus, Gregory J. Kaczorowski, Siegmund G. Wanner, Robert O. A. Koch, Maria Trieb, Maria L. Garcia
Publikováno v:
Biochemistry. 38:5392-5400
In rat brain, high-conductance Ca2+-activated K+ (BK) channels are targeted to axons and nerve terminals [Knaus, H. G., et al. (1996) J. Neurosci. 16, 955-963], but absolute levels of their regional expression and subunit composition have not yet bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8720976d644bb581dbf61ef4752fb77
https://doi.org/10.1021/bi983040c
https://doi.org/10.1021/bi983040c
Publikováno v:
Nature. 391:390-393
Shaker-related voltage-gated K+ (Kv) channels are assembled from ion-conducting K(v)alpha subunits, which are integral membrane proteins, and auxiliary K(v)beta subunits. This leads to the formation of highly diverse heteromultimeric Kv channels that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a25796baf8061d46560c63c0e8f0be8
https://doi.org/10.1038/34916
https://doi.org/10.1038/34916
Autor:
Robert O. A. Koch, Robert S. Slaughter, Hans-Günther Knaus, Siegmund G. Wanner, Markus Hanner, Maria L. Garcia, Alexandra Koschak, Christoph Schwarzer, Gregory J. Kaczorowski
Publikováno v:
Journal of Biological Chemistry. 272:27577-27581
Neurons require specific patterns of K+ channel subunit expression as well as the precise coassembly of channel subunits into heterotetrameric structures for proper integration and transmission of electrical signals. In vivo subunit coassembly was in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25ca68b76d516b4bb626ce07d77764b9
https://doi.org/10.1074/jbc.272.44.27577
https://doi.org/10.1074/jbc.272.44.27577
Autor:
Hans-Günther Knaus, Siegmund G. Wanner, Maria L. Garcia, Reid J. Leonard, John P. Felix, Gregory J. Kaczorowski, Randal M. Bugianesi, Robert O. A. Koch, Scott P. Stevens, Lisa M. H. Helms, Robert S. Slaughter
Publikováno v:
Biochemistry. 36:3737-3744
Voltage-gated potassium (K(V)) channels play key roles in setting the resting potential and in the activation cascade of human peripheral T lymphocytes. Margatoxin (MgTX), a 39-amino acid peptide from Centruroides margaritatus, is a potent inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d0a880467e6b335261e03716c0f3af7
https://doi.org/10.1021/bi962351p
https://doi.org/10.1021/bi962351p
Autor:
Kathryn M. Gauthier, Maria Trieb, Hans-Guenther Knaus, Nancy J. Rusch, Robert Koch, Alexandra Koschak, Siegmund G. Wanner
Publikováno v:
Potassium Channels in Cardiovascular Biology ISBN: 9781461354871
K+ channels represent a large and diverse group of ion channels that play a fundamental role in controlling cell excitability. These channels regulate hormone release from endocrine cells, modulate the pattern of transmitter release from neurons, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cabe0573b9014be86d95cb6631b6f11
https://doi.org/10.1007/978-1-4615-1303-2_6
https://doi.org/10.1007/978-1-4615-1303-2_6
Autor:
Alois Saria, Robert O. A. Koch, Christian Humpel, Hans-Günther Knaus, H. Fischer, Siegmund G. Wanner, Stefan Telser, Maria L. Garcia, Christine V Seidl
Publikováno v:
European journal of pharmacology. 343(2-3)
The distribution of iodinated margatoxin ([125I]margatoxin) binding sites in rat was investigated by autoradiography. Rat striatum expresses a high density of margatoxin binding sites and, therefore, the effects of margatoxin, charybdotoxin and iberi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f40aa2198cd4152ed3ba288542b4c6a
https://pubmed.ncbi.nlm.nih.gov/9570467
https://pubmed.ncbi.nlm.nih.gov/9570467