Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Siegfried W. Schoen"'
Autor:
Ingmar Blümcke, Heinz Beck, Christian E. Elger, Ailing A. Lie, Otmar D. Wiestler, Siegfried W. Schoen
Publikováno v:
Journal of Neuropathology and Experimental Neurology. 58:451-458
The localization and morphological assessment of plastic or newly formed synapses in the human brain remains difficult due to the lack of specific markers. The ectoenzyme 5'-nucleotidase may represent a useful marker of these structures, since in adu
Autor:
Georg W. Kreutzberg, Jean Mariani, Yannick Bailly, Nicole Delhaye-Bouchaud, Siegfried W. Schoen
Publikováno v:
Synapse. 29:279-292
During postnatal development of the rodent cerebellum, a transient enzyme activity of ecto-5′-nucleotidase has been shown in the asymmetrical synapses of Purkinje cells. The alterations of the afferent circuitry and microenvironment of the ectopic
Publikováno v:
Experimental Neurology. 127:106-118
In development, the ectoenzyme 5′-nucleotidase marks maturing cerebellar and cortical synapses, but it is localized in glial cells in the normal, adult nervous system. With a histochemical lead technique, we have now investigated its localization d
Autor:
Ann M. Graybiel, Siegfried W. Schoen
Publikováno v:
The Journal of Comparative Neurology. 322:566-576
The distribution of the adenosine-producing ectoenzyme 5'-nucleotidase was studied by means of a histochemical lead technique in the caudoputamen of normal adult rats and of rats in which injections either of 6-hydroxydopamine in the medial forebrain
Publikováno v:
Glia. 6:314-317
The ecto-enzyme 5′-nucleotidase was localized immunocytochemically in the axotomized rat facial nucleus. As revealed by the monoclonal antibody 5N4–2,5′-nucleotidase immunoreactivity markedly increased on perineuronal microglia during the first
Publikováno v:
Brain Research. 567:283-289
The localization of 5′-nucleotidase, an adenosine-producing ectoenzyme, was studied by a cytochemical method in the superior cervical ganglion of the adult cat and guinea pig. The following subcellular sites of enzymatic activity were detected: (1)
Publikováno v:
Developmental Brain Research. 61:125-138
The transient appearance of 5'-nucleotidase, an adenosine-producing ecto-enzyme, was studied during specific stages of postnatal synaptogenesis in the rat cerebellum. For ultrastructural detection of 5'-nucleotidase activity, an enzyme-cytochemical t
Publikováno v:
The Journal of Comparative Neurology. 296:379-392
The distribution of the adenosine-producing ecto-enzyme 5′-nucleotidase was investigated histochemically in the visual cortex of normally reared and monocularly deprived kittens and cats. In normally reared kittens aged between 11 to 44 days, 5′-
Publikováno v:
Brain research. Brain research protocols. 1(1)
The demonstration of 5′-nucleotidase in neural tissue is achieved at both the light and electron microscopic levels by means of an enzyme cytochemical lead method, which is specific, sensitive and fast [13–15, 17] . By its activity this adenosine
Autor:
Ann M. Graybiel, Siegfried W. Schoen
Publikováno v:
The Journal of comparative neurology. 333(4)
The glycoprotein 5′-nucleotidase is a cell surface phosphatase and represents a new marker for striosomes in the adult rat caudoputamen. We report here on its developmental expression in the rat and mouse striatum, and show an unexpected converse 5