Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Siegfried N, Lodwig"'
Autor:
Siegfried N. Lodwig, Ernesto Juarez, David R. Glass, Marc A. Alvarez, Rodolfo A. Martinez, Erick Gabriel Ortiz, Clifford J. Unkefer
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 56:31-35
We have developed large-scale efficient procedures for the conversion of commercially available [(13) C]- or [(2) H3 ,(13) C]methanol and (13) CO2 or (13) C-labeled bromoacetic acid to 2-(phenylthio)[1,2-(13) C2 ]-, [1-(13) C]-, and [2-(13) C]acetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6742f1c1f5269d91b6dc407a9b661f8
https://doi.org/10.1002/jlcr.2991
https://doi.org/10.1002/jlcr.2991
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 55:211-222
13C labeled (>M + 4) metabolites of nitrogen and sulfur-based chemical warfare agent metabolites were prepared from readily available and 13C labeled commercial starting materials. The new chemical routes are efficient in the number of chemical steps
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0343008d5909afaacd9b3840e8fd5a61
https://doi.org/10.1002/jlcr.2929
https://doi.org/10.1002/jlcr.2929
Autor:
Yoshio Takeuchi, Tomoya Fujiwara, Taiki Murai, Tamiko Takahashi, Kenji Omata, Clifford J. Unkefer, Kuninobu Kabuto, Masaru Segawa, Siegfried N. Lodwig, Hidehito Fujisawa
Publikováno v:
Tetrahedron: Asymmetry. 19:847-856
Applications of the CFTA method, a new and reliable procedure for the determination of the absolute configuration of chiral primary amines, are described in detail. In addition to the very high reactivity of CFTA chloride, the stable anti-periplanar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::412f495d07a4ef0dbebc8d4d00293922
https://doi.org/10.1016/j.tetasy.2008.03.003
https://doi.org/10.1016/j.tetasy.2008.03.003
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 41:983-991
We have developed a stereoselective route to the synthesis of stable isotope-labeled L-proline. Alkylation of (2R)-N-(N'-[bis(methylthio)methylidene}-glycyl)bornane-10,2-sultam with 3-chloro-iodopropane yielded (2R)-N-{(2'S)-2'-([Bis(methylthio)methy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5230f60856552402db87710456ca52e5
https://doi.org/10.1002/(sici)1099-1344(1998110)41:11<983::aid-jlcr152>3.0.co
https://doi.org/10.1002/(sici)1099-1344(1998110)41:11<983::aid-jlcr152>3.0.co
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 38:239-248
Using 1-chloro-1-[ 15 N]nitrosocyclohexane, we have prepared five L-[α- 15 N]amino acids. The stereoselective electophillic hydroxyamination of (S)-acylbornane-10,2-sultams, followed by Zn°/H + reduction, and alkaline cleavage of the chiral auxilia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87a91e0865ac0c39f3eab69479ad7e38
https://doi.org/10.1002/(sici)1099-1344(199603)38:3<239::aid-jlcr831>3.0.co
https://doi.org/10.1002/(sici)1099-1344(199603)38:3<239::aid-jlcr831>3.0.co
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 38:161-167
We have prepared 1-chloro-1-[ 15 N]nitrosocyclohexane, an electrophillic aminating reagent useful for the stereoselective synthesis of α-[ 15 N]amino acids. Treatment of potassium [ 15 N]nitrate with Pb° gave potassium [ 15 N]nitrite, which was con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8759c9dc285755ab839571a6144c993a
https://doi.org/10.1002/(sici)1099-1344(199602)38:2<161::aid-jlcr830>3.0.co
https://doi.org/10.1002/(sici)1099-1344(199602)38:2<161::aid-jlcr830>3.0.co
Autor:
Rodolfo A, Martinez, David R, Glass, Erick G, Ortiz, Marc A, Alvarez, Ernesto, Juarez, Siegfried N, Lodwig, Clifford J, Unkefer
Publikováno v:
Journal of labelled compoundsradiopharmaceuticals. 56(2)
We have developed large-scale efficient procedures for the conversion of commercially available [(13) C]- or [(2) H3 ,(13) C]methanol and (13) CO2 or (13) C-labeled bromoacetic acid to 2-(phenylthio)[1,2-(13) C2 ]-, [1-(13) C]-, and [2-(13) C]acetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d1648b2a0dc248393c416c64380d12f9
https://pubmed.ncbi.nlm.nih.gov/24285279
https://pubmed.ncbi.nlm.nih.gov/24285279
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 31:95-102
We have developed a stereoselective route to isotopically labeled L-aspartic acid using L-serine as a chiral precursor. Labeled serine, prepared biosynthetically was N-protected by conversion to the N-t-Boc derivative. (N-t-Boc)-[3−13C]Serine is cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfe68d9a077febc8ac6d270450eb97b5
https://doi.org/10.1002/jlcr.2580310204
https://doi.org/10.1002/jlcr.2580310204
Autor:
Louis A. Silks, Deborah S. Ehler, Clifford J. Unkefer, Rowena Gibson, Siegfried N. Lodwig, John L. Hanners
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 29:1247-1256
We have developed a stereospecific chemomicrobiological synthesis of labeled tryptophan. L-[3-13C]Serine, [1-15N]- and [2-13C]indole were used as precursors for the synthesis of L-[β-13C]-, L-[1′-15N]-, and L-[2′-13C]tryptophan, respectively. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fa6c179400d2244e5db7e18d4bf6692
https://doi.org/10.1002/jlcr.2580291109
https://doi.org/10.1002/jlcr.2580291109
Autor:
Clifford J. Unkefer, Robert E. London, William A. Beard, Siegfried N. Lodwig, Rajendra Prasad, Samuel H. Wilson, Guanghua Gao
Determination of the protonation state of titratable protein residues is of critical importance for the interpretation of active site chemistry, as well as for understanding the role of electrostatic interactions in protein folding and stability. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc98b06b6a49319eb0efa5e46c33101b
https://europepmc.org/articles/PMC2846763/
https://europepmc.org/articles/PMC2846763/
