Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sieger A. Nelemans"'
Autor:
Barbora Waclawiková, Paulo Cesar Telles de Souza, Markus Schwalbe, Constantinos G. Neochoritis, Warner Hoornenborg, Sieger A. Nelemans, Siewert J. Marrink, Sahar El Aidy
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTIntestinal microbiota and microbiota-derived metabolites play a key role in regulating the host physiology. Recently, we have identified a gut-bacterial metabolite, namely 5-hydroxyindole, as a potent stimulant of intestinal motility via its
Externí odkaz:
https://doaj.org/article/bfc4e2f6d78e4fee9419d2cb3d2f3e4a
Autor:
Sebastiaan P. van Kessel, Hiltje R. de Jong, Simon L. Winkel, Sander S. van Leeuwen, Sieger A. Nelemans, Hjalmar Permentier, Ali Keshavarzian, Sahar El Aidy
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract Background Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by both motor and non-motor symptoms. Gastrointestinal tract dysfunction is one of the non-motor features, where constipation is reported as the
Externí odkaz:
https://doaj.org/article/5c0cd6a2d67849819e3d923f5a7b5f24
Autor:
Carmen Aranzamendi, Barbora Waclawiková, Sahar El Aidy, Sieger Adriaan Nelemans, Markus Schwalbe, Gertjan van Dijk, Amber Bullock
Publikováno v:
PLoS Biology
PLOS BIOLOGY, 19(1):e3001070. PUBLIC LIBRARY SCIENCE
PLoS Biology, Vol 19, Iss 1, p e3001070 (2021)
PLOS BIOLOGY, 19(1):e3001070. PUBLIC LIBRARY SCIENCE
PLoS Biology, Vol 19, Iss 1, p e3001070 (2021)
Microbial conversion of dietary or drug substrates into small bioactive molecules represents a regulatory mechanism by which the gut microbiota alters intestinal physiology. Here, we show that a wide variety of gut bacteria can metabolize the dietary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f118f0e380feee747ba95a245e90e02e
https://research.rug.nl/en/publications/9904667e-501e-4354-bbdd-a601e16fa291
https://research.rug.nl/en/publications/9904667e-501e-4354-bbdd-a601e16fa291
Autor:
Hiltje Riemke de Jong, Sieger Adriaan Nelemans, Ali Keshavarzian, Hjalmar P. Permentier, Sander S. van Leeuwen, Simon Laurens Winkel, Sebastiaan P van Kessel, Sahar El Aidy
Publikováno v:
BMC Biology
BMC Biology, Vol 18, Iss 1, Pp 1-14 (2020)
BMC Biology, 18(1):137. BioMed Central Ltd.
BMC Biology, Vol 18, Iss 1, Pp 1-14 (2020)
BMC Biology, 18(1):137. BioMed Central Ltd.
Background Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by both motor and non-motor symptoms. Gastrointestinal tract dysfunction is one of the non-motor features, where constipation is reported as the most comm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c19839926005ecf075a94d22c588b6d
https://doi.org/10.1186/s12915-020-00876-3
https://doi.org/10.1186/s12915-020-00876-3
Autor:
M. Haas Jimoh Akanbi, Sieger Adriaan Nelemans, Inge Baudoin, Eduard Post, Rick Rink, Anneke Kuipers, Gert N. Moll, A. Arkema-Meter
Publikováno v:
Journal of Pharmacological and Toxicological Methods, 61(2), 210-218
Introduction: The major hurdle in the application and delivery of peptide pharmaceuticals is their rapid in vivo breakdown. Methods: We here combined two approaches to stabilize peptide pharmaceuticals, introduction of D-amino acids and cyclization,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4710217aa8d61c86dc2cbf712518890d
https://research.rug.nl/en/publications/a0f4bb38-a151-4818-ada8-6ad4ddc1f56f
https://research.rug.nl/en/publications/a0f4bb38-a151-4818-ada8-6ad4ddc1f56f
Autor:
Johannes Boonstra, Sieger Adriaan Nelemans, A. Bierman, A. Feijen, P. T. Van Der Saag, S.W. de Laat, E.J.J. van Zoelen
Publikováno v:
Biochimica et Biophysica Acta (BBA)-Biomembranes, 692(3), 321. Elsevier
In this study the effects of experimental modifications of plasma membrane lipid lateral mobility on the electrical membrane properties and cation transport of mouse neuroblastoma cells, clone Neuro-2A, have been studied. Short-term supplementation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::778ee468f0a1ab741272dc3a23345e55
https://dspace.library.uu.nl/handle/1874/16938
https://dspace.library.uu.nl/handle/1874/16938
Autor:
Barbora Waclawiková, Amber Bullock, Markus Schwalbe, Carmen Aranzamendi, Sieger A Nelemans, Gertjan van Dijk, Sahar El Aidy
Publikováno v:
PLoS Biology, Vol 19, Iss 1, p e3001070 (2021)
Microbial conversion of dietary or drug substrates into small bioactive molecules represents a regulatory mechanism by which the gut microbiota alters intestinal physiology. Here, we show that a wide variety of gut bacteria can metabolize the dietary
Externí odkaz:
https://doaj.org/article/261209b04ceb48ad9889fc83a2640629