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Autor: Warnat-Herresthal S; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Schultze H; Hewlett Packard Enterprise, Houston, TX, USA., Shastry KL; Hewlett Packard Enterprise, Houston, TX, USA., Manamohan S; Hewlett Packard Enterprise, Houston, TX, USA., Mukherjee S; Hewlett Packard Enterprise, Houston, TX, USA., Garg V; Hewlett Packard Enterprise, Houston, TX, USA.; Mesh Dynamics, Bangalore, India., Sarveswara R; Hewlett Packard Enterprise, Houston, TX, USA., Händler K; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; PRECISE Platform for Single Cell Genomics and Epigenomics, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) and the University of Bonn, Bonn, Germany., Pickkers P; Department of Intensive Care Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands., Aziz NA; Population Health Sciences, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; Department of Neurology, Faculty of Medicine, University of Bonn, Bonn, Germany., Ktena S; 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece., Tran F; Department of Internal Medicine I, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Kiel, Germany.; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Kiel, Germany., Bitzer M; Department of Internal Medicine I, University Hospital, University of Tübingen, Tübingen, Germany., Ossowski S; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany.; NGS Competence Center Tübingen, Tübingen, Germany., Casadei N; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany.; NGS Competence Center Tübingen, Tübingen, Germany., Herr C; Department of Internal Medicine V, Saarland University Hospital, Homburg, Germany., Petersheim D; Department of Pediatrics, Dr. von Hauner Children's Hospital, University Hospital LMU Munich, Munich, Germany., Behrends U; Children's Hospital, Medical Faculty, Technical University Munich, Munich, Germany., Kern F; Clinical Bioinformatics, Saarland University, Saarbrücken, Germany., Fehlmann T; Clinical Bioinformatics, Saarland University, Saarbrücken, Germany., Schommers P; Department I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany., Lehmann C; Department I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany., Augustin M; Department I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany., Rybniker J; Department I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany., Altmüller J; Cologne Center for Genomics, West German Genome Center, University of Cologne, Cologne, Germany., Mishra N; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Kiel, Germany., Bernardes JP; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Kiel, Germany., Krämer B; Clinical Infectious Diseases, Research Center Borstel and German Center for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Borstel, Germany., Bonaguro L; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Schulte-Schrepping J; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., De Domenico E; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; PRECISE Platform for Single Cell Genomics and Epigenomics, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) and the University of Bonn, Bonn, Germany., Siever C; Hewlett Packard Enterprise, Houston, TX, USA., Kraut M; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; PRECISE Platform for Single Cell Genomics and Epigenomics, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) and the University of Bonn, Bonn, Germany., Desai M; Hewlett Packard Enterprise, Houston, TX, USA., Monnet B; Hewlett Packard Enterprise, Houston, TX, USA., Saridaki M; 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece., Siegel CM; Hewlett Packard Enterprise, Houston, TX, USA., Drews A; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; PRECISE Platform for Single Cell Genomics and Epigenomics, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) and the University of Bonn, Bonn, Germany., Nuesch-Germano M; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Theis H; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; PRECISE Platform for Single Cell Genomics and Epigenomics, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) and the University of Bonn, Bonn, Germany., Heyckendorf J; Clinical Infectious Diseases, Research Center Borstel and German Center for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Borstel, Germany., Schreiber S; Department of Internal Medicine I, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Kiel, Germany., Kim-Hellmuth S; Department of Pediatrics, Dr. von Hauner Children's Hospital, University Hospital LMU Munich, Munich, Germany., Nattermann J; Department of Internal Medicine I, University Hospital Bonn, Bonn, Germany.; German Center for Infection Research (DZIF), Braunschweig, Germany., Skowasch D; Department of Internal Medicine II - Cardiology/Pneumology, University of Bonn, Bonn, Germany., Kurth I; Institute of Human Genetics, Medical Faculty, RWTH Aachen University, Aachen, Germany., Keller A; Clinical Bioinformatics, Saarland University, Saarbrücken, Germany.; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA., Bals R; Department of Internal Medicine V, Saarland University Hospital, Homburg, Germany., Nürnberg P; Cologne Center for Genomics, West German Genome Center, University of Cologne, Cologne, Germany., Rieß O; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany.; NGS Competence Center Tübingen, Tübingen, Germany., Rosenstiel P; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Kiel, Germany., Netea MG; Department of Internal Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands.; Immunology & Metabolism, Life and Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Theis F; Institute of Computational Biology, Helmholtz Center Munich (HMGU), Neuherberg, Germany., Mukherjee S; Statistics and Machine Learning, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany., Backes M; CISPA Helmholtz Center for Information Security, Saarbrücken, Germany., Aschenbrenner AC; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.; PRECISE Platform for Single Cell Genomics and Epigenomics, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) and the University of Bonn, Bonn, Germany.; Department of Internal Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands., Ulas T; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Breteler MMB; Population Health Sciences, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; Institute for Medical Biometry, Informatics and Epidemiology (IMBIE), Faculty of Medicine, University of Bonn, Bonn, Germany., Giamarellos-Bourboulis EJ; 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece., Kox M; Department of Intensive Care Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands., Becker M; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; PRECISE Platform for Single Cell Genomics and Epigenomics, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) and the University of Bonn, Bonn, Germany., Cheran S; Hewlett Packard Enterprise, Houston, TX, USA., Woodacre MS; Hewlett Packard Enterprise, Houston, TX, USA., Goh EL; Hewlett Packard Enterprise, Houston, TX, USA., Schultze JL; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany. joachim.schultze@dzne.de.; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany. joachim.schultze@dzne.de.; PRECISE Platform for Single Cell Genomics and Epigenomics, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) and the University of Bonn, Bonn, Germany. joachim.schultze@dzne.de.

Publikováno v: Nature [Nature] 2021 Jun; Vol. 594 (7862), pp. 265-270. Date of Electronic Publication: 2021 May 26.