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Molecular characterization of colorectal adenomas reveals POFUT1 as a candidate driver of tumor progression

Autor: Komor, MA, Wit, M, Berg, J, de Kemp, SRM, Delis-van Diemen, PM, Bolijn, AS, Tijssen, M, Schelfhorst, T, Piersma, SR, Chiasserini, D, Sanders, J, Rausch, C, Hoogstrate, Youri, Stubbs, Andrew, Jong, M, Jenster, Guido, Carvalho, B, Meijer, GA, Jimenez, CR, Fijneman, RJA, Dits, Natasja, Böttcher, René, Hiemstra, AC, Ylstra, B, Sie, D, Broek, E, van Grieken, N, Meer, D, Pepers, F, Caldenhoven, E, Janssen, B, van Workum, W, van Lieshout, S, Bangma, C.H., van Leenders, Arno, van de Werken, Harmen

Publikováno v: International Journal of Cancer, 146(7), 1979-1992. Wiley-Liss Inc.
Komor, M A, de Wit, M, van den Berg, J, Martens de Kemp, S R, Delis-van Diemen, P M, Bolijn, A S, Tijssen, M, Schelfhorst, T, Piersma, S R, Chiasserini, D, Sanders, J, Rausch, C, Hoogstrate, Y, Stubbs, A P, de Jong, M, Jenster, G, Carvalho, B, Meijer, G A, Jimenez, C R, Fijneman, R J A & In collaboration with the NGS-ProToCol Consortium 2020, ' Molecular characterization of colorectal adenomas reveals POFUT1 as a candidate driver of tumor progression ', International Journal of Cancer, vol. 146, no. 7, pp. 1979-1992 . https://doi.org/10.1002/ijc.32627
International Journal of Cancer

Removal of colorectal adenomas is an effective strategy to reduce colorectal cancer (CRC) mortality rates. However, as only a minority of adenomas progress to cancer, such strategies may lead to overtreatment. The present study aimed to characterize

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0f18edb5b8a61777493b094f6c33b9d
https://doi.org/10.1002/ijc.32627

IBD-associated dysplastic lesions show more chromosomal instability than sporadic adenomas

Autor: Wanders, L.K., Cordes, M., Voorham, Q., Sie, D., Vries, S.D. de, d'Haens, G.R.A.M., Boer, N.K.H. de, Ylstra, B., Grieken, N.C.T. van, Meijer, G.A., Dekker, E., Carvalho, B.

Inflammatory bowel disease (IBD) patients are at increased risk of developing colorectal cancer. However, histologically, it is challenging to distinguish between IBD-associated dysplasia from sporadic adenomas. We have molecularly characterized thes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______202::f87ac7ebf878e0c8861e3eea6372eb74
https://hdl.handle.net/1887/3627354

Genome-wide microRNA analysis of HPV-positive self-samples yields novel triage markers for early detection of cervical cancer

Autor: Snoek, BC, Verlaat, W, Babion, I, Novianti, P W, van de Wiel, MA, Wilting, Saskia, van Trommel, NE, Bleeker, MCG, Massuger, L, Melchers, WJG, Sie, D, Heideman, DAM, Snijders, PJF, Meijer, C, Steenbergen, RDM

Publikováno v: International Journal of Cancer, 144(2), 372-379. Wiley-Liss Inc.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::0fcdc727e9a43cfe36f73a615263a9ae
https://pure.eur.nl/en/publications/b23b09be-1b5b-4c89-8373-b8b595e9698c

Consensus molecular subtype classification of colorectal adenomas

Autor: Komor, MA, Bosch, L J W, Bounova, G, Bolijn, AS, Delis-van Diemen, PM, Rausch, C, Hoogstrate, Youri, Stubbs, Andrew, Jong, M, Jenster, Guido, van Grieken, NCT, Carvalho, B, Wessels, LFA, Jimenez, CR, Fijneman, RJA, Meijer, GA, Dits, NFJ, Böttcher, René, Hiemstra, AC, Ylstra, B, Sie, D, Broek, E, Meer, D, Pepers, F, Caldenhoven, E, Janssen, B, van Workum, W, van Lieshout, S, Bangma, CH, van Leenders, Arno, de Werken, HV

Publikováno v: Journal of Pathology, 246(3), 266-276. John Wiley & Sons Ltd.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::22d594442301eae66f34662044606bed
https://pure.eur.nl/en/publications/3419d14f-4be0-4d7d-aadb-9b6e9423f2f7