Marker-free CRISPR-Cas9 based genetic engineering of the phytopathogenic fungus, Penicillium expansum

Autor: Sidsel Ettrup Clemmensen, Rasmus John Normand Frandsen, Kresten Jon Korup Kromphardt

Publikováno v: Clemmensen, S E, Kromphardt, K J K & Frandsen, R J N 2022, ' Marker-free CRISPR-Cas9 based genetic engineering of the phytopathogenic fungus, Penicillium expansum ', Fungal Genetics and Biology, vol. 160, 103689 . https://doi.org/10.1016/j.fgb.2022.103689

Filamentous fungi are prolific producers of secondary metabolites (SecMets), including compounds with antibiotic properties, like penicillin, that allows the producing fungus to combat competitors in a shared niche. However, the biological function o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8011207706e70d0da1cba0d7ecb75b75
https://pubmed.ncbi.nlm.nih.gov/35339702

Production of benzylglucosinolate by engineering and optimizing the biosynthetic pathway in Saccharomyces cerevisiae

Autor: Christina Spuur Nødvig, Uffe Hasbro Mortensen, Barbara Ann Halkier, Cuiwei Wang, Christoph Crocoll, Sidsel Ettrup Clemmensen

Glucosinolates are amino acid-derived defense compounds characteristic of the Brassicales order. Benzylglucosinolate (BGLS) derived from phenylalanine is associated with health-promoting effects, which has primed a desire to produce BGLS in microorga

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c6cd49af057f4abb6ec4ab94c5bcb56c
https://doi.org/10.1101/2020.07.08.193391