Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sidra Islam"'
Autor:
Mohd Mustafa, Kashif Abbas, Mudassir Alam, Safia Habib, Zulfareen, Gulam Mustafa Hasan, Sidra Islam, Anas Shamsi, Imtaiyaz Hassan
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Pancreatic adenocarcinoma, a clinically challenging malignancy constitutes a significant contributor to cancer-related mortality, characterized by an inherently poor prognosis. This review aims to provide a comprehensive understanding of pancreatic a
Externí odkaz:
https://doaj.org/article/f95f9bfc3e18409cbe58922eb28706d6
Autor:
Pranjal Biswas, Joseph Palazzo, Simon Schlanger, Dhanya Thamaraparambil Jayaram, Sidra Islam, Richard C. Page, Dennis J. Stuehr
Publikováno v:
Redox Biology, Vol 71, Iss , Pp 103120- (2024)
Iron protoporphyrin IX (heme) is a redox-active cofactor that is bound in mammalian cells by GAPDH and allocated by a process influenced by physiologic levels of NO. This impacts the activity of many heme proteins including indoleamine dioxygenase-1
Externí odkaz:
https://doaj.org/article/33661509588b42689a85f3e9e0aeb44e
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169099 (2017)
Glycoxidation plays a crucial role in diabetes and its associated complications. Among the glycoxidation agents, methylglyoxal (MG) is known to have very highglycationpotential witha concomitant generation of reactive oxygen species (ROS) during its
Externí odkaz:
https://doaj.org/article/59d0be12af72402e97121ba6f43ba3ae
Autor:
Sidra Islam, Michael T. Do, Brett S. Frank, Grant L. Hom, Samuel Wheeler, Hisashi Fujioka, Benlian Wang, Geeta Minocha, David R. Sell, Xingjun Fan, Kirsten J. Lampi, Vincent M. Monnier
Publikováno v:
Journal of Biological Chemistry. 298:102417
Γ-Crystallins play a major role in age-related lens transparency. Their destabilization by mutations and physical chemical insults are associated with cataract formation. Therefore, drugs that increase their stability should have anticataract proper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e17911fbbc6a05648d94a0c6aa29180
https://doi.org/10.1016/j.jbc.2022.102417
https://doi.org/10.1016/j.jbc.2022.102417
Autor:
Minhal Abidi, Mohd Sharib Warsi, Sidra Islam, Safia Habib, Moinuddin, Mohd Talha, Abdul Rouf Mir
Publikováno v:
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 255
Reactive oxygen species (ROS) cause oxidative damage to proteins and generate deleterious by-products which induce a breakdown of immune tolerance and produce antibodies against host macromolecules with implication in human diseases. This study chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6c98230c58c5424795788d1da334a01
https://pubmed.ncbi.nlm.nih.gov/33744841
https://pubmed.ncbi.nlm.nih.gov/33744841
Autor:
Saheem Ahmad, Minhal Abidi, M. Salman Khan, Shahid M. Nayeem, Khursheed Alam, Sidra Islam, Asif Ali, Moinuddin, Tasneem Kausar
Publikováno v:
Archives of Biochemistry and Biophysics. 645:87-99
Methylglyoxal (MGO), a reactive dicarbonyl metabolite is a potent arginine directed glycating agent which has implications for diabetes-related complications. Dicarbonyl metabolites are produced endogenously and in a state of misbalance, they contrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::858bf62416c80836ce69313905b925e8
https://doi.org/10.1016/j.abb.2018.02.019
https://doi.org/10.1016/j.abb.2018.02.019
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 36:2637-2653
Glycation and oxidation induce structural alterations in the proteins in an interdependent manner with consequent pathological implications. The published literature presents wide range of modifications in conformational characteristics of proteins b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e4839a31f006e4a49ba0398d29e925
https://doi.org/10.1080/07391102.2017.1365770
https://doi.org/10.1080/07391102.2017.1365770
Autor:
Masood A. Khan, Yosef H. Aldebasi, Mohammed S. Alorainy, Hina Younus, Ahmed N. Aljarbou, Sidra Islam, Sana Anwar
Publikováno v:
International journal of biological macromolecules. 139
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcdcf8945ae41ccac614ced0e9904a9d
https://pubmed.ncbi.nlm.nih.gov/24412154
https://pubmed.ncbi.nlm.nih.gov/24412154
Publikováno v:
International Journal of Biological Macromolecules. 86:145-154
Non-enzymatic lipid peroxidation of cellular membranes occurs during periods of sustained oxidative stress. 4-Hydroxynonenal (HNE), the most reactive lipid peroxidation product, is capable of modifying and/or cross-linking proteins leading to impaire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bd2f663b6b2b2386ec85c6e8d922a4d
https://doi.org/10.1016/j.ijbiomac.2016.01.053
https://doi.org/10.1016/j.ijbiomac.2016.01.053
Publikováno v:
Clinica Chimica Acta. 453:48-55
Background Novel immunological epitopes upon glyoxidation modified proteins have been discovered and multi-specific natural antibodies against them have been identified. The association of glyoxidation with cancer has also been reported. We probed th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a1d96bcaa71857070e18184e87c6de8
https://doi.org/10.1016/j.cca.2015.12.004
https://doi.org/10.1016/j.cca.2015.12.004