Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sidra, Ellis"'
Autor:
John R. Jones, Niels Weinhold, Cody Ashby, Brian A. Walker, Chris Wardell, Charlotte Pawlyn, Leo Rasche, Lorenzo Melchor, David A. Cairns, Walter M. Gregory, David Johnson, Dil B. Begum, Sidra Ellis, Amy L. Sherborne, Gordon Cook, Martin F. Kaiser, Mark T. Drayson, Roger G. Owen, Graham H. Jackson, Faith E. Davies, Mel Greaves, Gareth J. Morgan
Publikováno v:
Haematologica, Vol 104, Iss 7 (2019)
The emergence of treatment resistant sub-clones is a key feature of relapse in multiple myeloma. Therapeutic attempts to extend remission and prevent relapse include maximizing response and the use of maintenance therapy. We used whole exome sequenci
Externí odkaz:
https://doaj.org/article/a86d654622214f9181635aa884fb5db7
Autor:
Vallari, Shah, Amy L, Sherborne, David C, Johnson, Sidra, Ellis, Amy, Price, Farzana, Chowdhury, Jack, Kendall, Matthew W, Jenner, Mark T, Drayson, Roger G, Owen, Walter M, Gregory, Gareth J, Morgan, Faith E, Davies, Gordon, Cook, David A, Cairns, Richard S, Houlston, Graham, Jackson, Martin F, Kaiser, Kikkeri, Naresh
Publikováno v:
Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b93f7f9b4b8f0bc7724ad9c933ea74
https://doi.org/10.1038/s41375-020-0750-z
https://doi.org/10.1038/s41375-020-0750-z
Autor:
James Croft, Hannah Hunter, Richard S. Houlston, Amy Price, David A Cairns, Jindriska Lindsay, Matthew W Jenner, Gordon Cook, Suvi Savola, Kamaraj Karunanithi, Mark T. Drayson, Gareth J. Morgan, Lilit Atanesyan, Amy L. Sherborne, Walter M Gregory, Martin Kaiser, Sidra Ellis, Roger G. Owen, Kim Sharp, Sally Chown, Graham Jackson, Faith E. Davies
Publikováno v:
Leukemia
Structural chromosomal changes including copy number aberrations (CNAs) are a major feature of multiple myeloma (MM), however their evolution in context of modern biological therapy is not well characterized. To investigate acquisition of CNAs and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7ea149524012617cb985aea72ca61c
Autor:
Amy L. Sherborne, Faith E. Davies, David A Cairns, Mark T. Drayson, Mel Greaves, Niels Weinhold, Sidra Ellis, Cody Ashby, Christopher P. Wardell, David W. Johnson, Gordon Cook, Martin Kaiser, Roger G. Owen, Gareth J. Morgan, Charlotte Pawlyn, Graham Jackson, Brian A Walker, John R Jones, Lorenzo Melchor, Walter M Gregory, Dil B Begum, Leo Rasche
Publikováno v:
Haematologica. 104(7)
The emergence of treatment resistant sub-clones is a key feature of relapse in multiple myeloma. Therapeutic attempts to extend remission and prevent relapse include maximizing response and the use of maintenance therapy. We used whole exome sequenci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e5e7a55b7b37d3379555323fb8a954
https://pubmed.ncbi.nlm.nih.gov/31257204
https://pubmed.ncbi.nlm.nih.gov/31257204
Autor:
Amy L. Sherborne, William E. Pierceall, Sidra Ellis, Martin Kaiser, Kim Sharp, Kevin Boyd, Andrew J. Hall, Charlotte Pawlyn, Anjan Thakurta, Mamta Garg, James Croft, Suzana Couto, Sarah Brown, Gordon Cook, Katrina Walker, Maria Wang, Louise Flanagan, Amy Price
Publikováno v:
Blood. 134:4327-4327
Background Treatment of relapsed/refractory multiple myeloma (RRMM) remains challenging as durable remissions are achieved in patient sub-groups only. Identifying patients that are likely to benefit prior to or early after starting relapse treatments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f364f0fb2403b5608d9385abef8a211b
https://doi.org/10.1182/blood-2019-123640
https://doi.org/10.1182/blood-2019-123640
Autor:
Mark T. Drayson, Katrina Walker, Sarah Brown, Amy Price, Guy Pratt, Andrew J. Hall, Vallari Shah, Martin Kaiser, Louise Flanagan, Ruth M. de Tute, Roger G. Owen, James Croft, Amy L. Sherborne, Graham Jackson, Sidra Ellis, Gordon Cook, Matthew W Jenner, Kim Sharp
Publikováno v:
Blood. 134:3162-3162
Background High-risk myeloma patients have unsatisfactory outcomes with current treatments and are in urgent need of improved diagnostic and therapeutic strategies. We have recently validated specific markers predicting high-risk disease in newly dia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8ebcc28ba86eaa783e245208ac96dcf
https://doi.org/10.1182/blood-2019-123547
https://doi.org/10.1182/blood-2019-123547
Autor:
David A Cairns, Mark T. Drayson, John R Jones, Brian A Walker, Charlotte Pawlyn, Charlotte Smith, Graham Jackson, Martin Kaiser, Lorenzo Melchor, Matthew Jenner, Nigel H. Russell, Niels Weinhold, Faith E. Davies, Amy L. Sherborne, Sidra Ellis, Dil B Begum, Christopher P. Wardell, David W. Johnson, Mel Greaves, Shweta S. Chavan, Amy Price, Gareth J. Morgan, Gordon Cook, Roger G. Owen, Walter M Gregory
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 17:e100-e101
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f926768d198706fbe1c7370d5a113a0d
https://doi.org/10.1016/j.clml.2017.03.181
https://doi.org/10.1016/j.clml.2017.03.181
Autor:
Amy L. Sherborne, Irene Moreno Candilejo, Udai Banerji, Martin Kaiser, Priya Sriskandarajah, Wen Xu, Juanita Lopez, Kevin Boyd, J.C. Dawes, James Croft, Mona Parmar, Amy Price, Vallari Shah, Alison Turner, Nina Tunariu, Johann S. de Bono, Emma Hall, Sidra Ellis
Publikováno v:
Blood. 132:3237-3237
Background Mutations of RAF/RAS genes are one of the most common oncogenic events in multiple myeloma. Therapeutic targeting of RAF/RAS/MAPK signalling using small molecule inhibitors has led to significant responses in solid cancers. Recently, combi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66e1d90a8b035885460b62055daa8fc4
https://doi.org/10.1182/blood-2018-99-111821
https://doi.org/10.1182/blood-2018-99-111821
Autor:
Amy Price, Alina Striha, Vallari Shah, Faith E. Davies, Graham Jackson, Matthew W Jenner, David W. Johnson, David A Cairns, Richard S. Houlston, Gareth J. Morgan, Laura Chiecchio, Roger G. Owen, Sidra Ellis, Jack Kendall, Charlotte Pawlyn, Anna Hockaday, Walter M Gregory, Gordon Cook, Martin Kaiser, Amy L. Sherborne, Mark T. Drayson
Publikováno v:
Blood. 132:2000-2000
INTRODUCTION Features of high risk myeloma (MM) have been studied in detail but patients with longer term responses to first-line therapy are less well characterised. Identification of common features of this group may support optimised management. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a644018576c189303d9a1119467f7b77
https://doi.org/10.1182/blood-2018-99-110149
https://doi.org/10.1182/blood-2018-99-110149
Autor:
Debbie Sherratt, Martin Kaiser, James Croft, Kevin Boyd, Katrina Walker, Andrew J. Hall, Amy Price, Sadie Reed, Mamta Garg, Sarah Brown, Amy L. Sherborne, Sidra Ellis, Gordon Cook, Charlotte Pawlyn
Publikováno v:
Blood. 132:3274-3274
Background and aims Treatment of relapsed/refractory myeloma (RRMM) remains a challenge as most approved and commonly accessible doublet treatments induce responses (≥PR) in less than half of patients. The combination of the classical alkylator cyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07b6744555d611839be31d540be49468
https://doi.org/10.1182/blood-2018-99-111835
https://doi.org/10.1182/blood-2018-99-111835