Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sidonie Vivequin"'
Autor:
John R B Perry, Benjamin F Voight, Loïc Yengo, Najaf Amin, Josée Dupuis, Martha Ganser, Harald Grallert, Pau Navarro, Man Li, Lu Qi, Valgerdur Steinthorsdottir, Robert A Scott, Peter Almgren, Dan E Arking, Yurii Aulchenko, Beverley Balkau, Rafn Benediktsson, Richard N Bergman, Eric Boerwinkle, Lori Bonnycastle, Noël P Burtt, Harry Campbell, Guillaume Charpentier, Francis S Collins, Christian Gieger, Todd Green, Samy Hadjadj, Andrew T Hattersley, Christian Herder, Albert Hofman, Andrew D Johnson, Anna Kottgen, Peter Kraft, Yann Labrune, Claudia Langenberg, Alisa K Manning, Karen L Mohlke, Andrew P Morris, Ben Oostra, James Pankow, Ann-Kristin Petersen, Peter P Pramstaller, Inga Prokopenko, Wolfgang Rathmann, William Rayner, Michael Roden, Igor Rudan, Denis Rybin, Laura J Scott, Gunnar Sigurdsson, Rob Sladek, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Jaakko Tuomilehto, Andre G Uitterlinden, Sidonie Vivequin, Michael N Weedon, Alan F Wright, MAGIC, DIAGRAM Consortium, GIANT Consortium, Frank B Hu, Thomas Illig, Linda Kao, James B Meigs, James F Wilson, Kari Stefansson, Cornelia van Duijn, David Altschuler, Andrew D Morris, Michael Boehnke, Mark I McCarthy, Philippe Froguel, Colin N A Palmer, Nicholas J Wareham, Leif Groop, Timothy M Frayling, Stéphane Cauchi
Publikováno v:
PLoS Genetics, Vol 8, Iss 5, p e1002741 (2012)
Common diseases such as type 2 diabetes are phenotypically heterogeneous. Obesity is a major risk factor for type 2 diabetes, but patients vary appreciably in body mass index. We hypothesized that the genetic predisposition to the disease may be diff
Externí odkaz:
https://doaj.org/article/69278706f1ba4c3e8b31e43c60a600aa
Autor:
David Altschuler, Cornelia M. van Duijn, Igor Rudan, Denis Rybin, Yann Labrune, Francis S. Collins, Martha Ganser, Lu Qi, Michael Roden, Unnur Thorsteinsdottir, Inga Prokopenko, Albert Hofman, Guillaume Charpentier, Mark I. McCarthy, Robert Sladek, James F. Wilson, Stéphane Cauchi, Yurii S. Aulchenko, Christian Herder, Robert A. Scott, Man Li, Peter P. Pramstaller, Rafn Benediktsson, Frank B. Hu, Samy Hadjadj, Peter Almgren, Andrew D. Johnson, Beverley Balkau, Pau Navarro, Michael Boehnke, Michael N. Weedon, Leif Groop, John R. B. Perry, Lori L. Bonnycastle, Noël P. Burtt, Alisa K. Manning, Claudia Langenberg, W Rayner, Benjamin F. Voight, Wolfgang Rathmann, Timothy M. Frayling, Gunnar Sigurdsson, Eric Boerwinkle, James S. Pankow, Ben A. Oostra, Andrew D. Morris, Philippe Froguel, Linda Kao, Dan E. Arking, Kari Stefansson, Harry Campbell, Loic Yengo, Colin N. A. Palmer, Nicholas J. Wareham, James B. Meigs, Karen L. Mohlke, Gudmar Thorleifsson, Andrew T. Hattersley, Alan F. Wright, Laura J. Scott, Harald Grallert, Jaakko Tuomilehto, Najaf Amin, Christian Gieger, Thomas Illig, Anna Köttgen, Todd Green, Josée Dupuis, Sidonie Vivequin, Richard N. Bergman, Peter Kraft, André G. Uitterlinden, Valgerdur Steinthorsdottir, Andrew P. Morris, Ann-Kristin Petersen
Publikováno v:
PLoS Genetics
PLoS Genet. 8:e1002741 (2012)
PLoS Genetics (print), 8(5). Public Library of Science
PLoS Genetics; 8(5) (2012)
PLoS Genetics; Vol 8
Perry, J R B, Voight, B F, Yengo, L, Amin, N, Dupuis, J, Ganser, M, Grallert, H, Navarro, P, Li, M, Qi, L, Steinthorsdottir, V, Scott, R A, Almgren, P, Arking, D E, Aulchenko, Y, Balkau, B, Benediktsson, R, Bergman, R N, Boerwinkle, E, Bonnycastle, L, Burtt, N P, Campbell, H, Charpentier, G, Collins, F S, Gieger, C, Green, T, Hadjadj, S, Hattersley, A T, Herder, C, Hofman, A, Johnson, A D, Kottgen, A, Kraft, P, Labrune, Y, Langenberg, C, Manning, A K, Mohlke, K L, Morris, A P, Oostra, B, Pankow, J, Petersen, A-K, Pramstaller, P P, Prokopenko, I, Rathmann, W, Rayner, W, Roden, M, Rudan, I, Wright, A F & Wilson, J F & Morris, A 2012, ' Stratifying Type 2 Diabetes Cases by BMI Identifies Genetic Risk Variants in LAMA1 and Enrichment for Risk Variants in Lean Compared to Obese Cases ', PLoS Genetics, vol. 8, no. 5, e1002741, pp. 1-14 . https://doi.org/10.1371/journal.pgen.1002741
PLoS Genetics, Vol 8, Iss 5, p e1002741 (2012)
PLoS Genet. 8:e1002741 (2012)
PLoS Genetics (print), 8(5). Public Library of Science
PLoS Genetics; 8(5) (2012)
PLoS Genetics; Vol 8
Perry, J R B, Voight, B F, Yengo, L, Amin, N, Dupuis, J, Ganser, M, Grallert, H, Navarro, P, Li, M, Qi, L, Steinthorsdottir, V, Scott, R A, Almgren, P, Arking, D E, Aulchenko, Y, Balkau, B, Benediktsson, R, Bergman, R N, Boerwinkle, E, Bonnycastle, L, Burtt, N P, Campbell, H, Charpentier, G, Collins, F S, Gieger, C, Green, T, Hadjadj, S, Hattersley, A T, Herder, C, Hofman, A, Johnson, A D, Kottgen, A, Kraft, P, Labrune, Y, Langenberg, C, Manning, A K, Mohlke, K L, Morris, A P, Oostra, B, Pankow, J, Petersen, A-K, Pramstaller, P P, Prokopenko, I, Rathmann, W, Rayner, W, Roden, M, Rudan, I, Wright, A F & Wilson, J F & Morris, A 2012, ' Stratifying Type 2 Diabetes Cases by BMI Identifies Genetic Risk Variants in LAMA1 and Enrichment for Risk Variants in Lean Compared to Obese Cases ', PLoS Genetics, vol. 8, no. 5, e1002741, pp. 1-14 . https://doi.org/10.1371/journal.pgen.1002741
PLoS Genetics, Vol 8, Iss 5, p e1002741 (2012)
Common diseases such as type 2 diabetes are phenotypically heterogeneous. Obesity is a major risk factor for type 2 diabetes, but patients vary appreciably in body mass index. We hypothesized that the genetic predisposition to the disease may be diff
Autor:
Wieland Kiess, Philippe Froguel, Atsuhiko Ichimura, Fritz F. Horber, Marjo-Riitta Järvelin, Maithé Tauber, Kentaro Ozawa, Hélène Choquet, André Scherag, Takafumi Hara, Akira Hirasawa, François Pattou, Philippe Besnard, Anastasia Kouvatsi, Johannes Hebebrand, Gozoh Tsujimoto, Paul Elliott, Odile Poulain-Godefroy, Cécile Lecoeur, Konstantinos Rouskas, Wim Van Hul, Marie Pigeyre, Kumiko Ayukawa, Audrey Leloire, Claudio Maffeis, Ikuo Kimura, Antje Körner, Raffaella Buzzetti, Roberto Caiazzo, Taka-aki Koshimizu, Keiko Iida, Beverley Balkau, Anneli Pouta, Sidonie Vivequin, David Meyre, Ning Liu, Anke Hinney, Luc Van Gaal, Masato Takeuchi, Isabelle Wolowczuk, Loic Yengo, Anita Morandi, Claire Levy-Marchal, Amélie Bonnefond
Publikováno v:
Nature
Nature; Vol 483
Nature; Vol 483
Free fatty acids provide an important energy source as nutrients, and act as signalling molecules in various cellular processes. Several G-protein-coupled receptors have been identified as free-fatty-acid receptors important in physiology as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d1b7c5b530fa98f31d660cdfc6b7b5
https://www.ncbi.nlm.nih.gov/pubmed/22343897
https://www.ncbi.nlm.nih.gov/pubmed/22343897
Autor:
Stéphane Lobbens, Guillaume Charpentier, Marlène Huyvaert, Stéphane Cauchi, Philippe Froguel, B. Balkau, Sidonie Vivequin, Marcel Marquez
Publikováno v:
Diabetes & Metabolism. 37:A66
Introduction Des etudes anterieures ont montre l'importance d'un cofacteur de transcription nomme HMGA1 dans la regulation de l'expression du recepteur a l'insuline, INSR. En effet, les souris Hmga1–/– developpent une insulino-resistance associee
Autor:
Laurent Rigal, Elodie Perrodeau, Claire Le Jeunne, Philippe Jaury, Jean-Marc Tréluyer, Stéphanie Sidorkiewicz, Raphaël Porcher
Publikováno v:
Addiction
Addiction, Wiley, 2020, 115 (7), pp.1265-1276. ⟨10.1111/add.14927⟩
Addiction, Wiley, 2020, 115 (7), pp.1265-1276. ⟨10.1111/add.14927⟩
Background and aims Baclofen is a promising drug for treating patients with alcohol-related disorders. Nevertheless, the first randomized clinical trials (mainly with target doses) reported inconsistent efficacy, possibly because of the effective dos