Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Sidney S. Schreiber"'
Autor:
Murray Oratz, Marcus A. Rothschild, Barbara Matarese, Joseph Mongelli, Sidney S. Schreiber, Alvin Burks
Publikováno v:
Hepatology. 3:567-571
Albumin synthesis is stimulated by those amino acids which increase urea synthesis and membrane bound polysome aggregation. Ornithine, an amino acid not incorporated into protein and produced from arginine in the urea cycle, is an albumin-stimulating
Publikováno v:
Ciba Foundation Symposium 9-Protein Turnover
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2f3eb16b5afe30f02d5a07a6ca95945
https://doi.org/10.1002/9780470719923.ch8
https://doi.org/10.1002/9780470719923.ch8
Publikováno v:
Journal of Molecular and Cellular Cardiology. 6:207-213
Previous studies in this laboratory had shown that while ethanol at levels of 200 to 300 mg 100 ml had no effect on cardiac protein synthesis, acetaldehyde ( 3.5 mg 100 ml or 0.8 m m ) markedly inhibited cardiac protein synthesis in the intact heart
Publikováno v:
Alcoholism: Clinical and Experimental Research. 10:531-534
Prolonged ingestion of ethanol may lead to a cardiomyopathy, and studies in the experimental animal have demonstrated alterations in protein metabolism. These changes include depression of protein synthesis with acetaldehyde in the acute experiment,
Effect of hydrostatic pressure on isolated cardiac nuclei: stimulation of RNA polymerase II activity
Publikováno v:
Cardiovascular Research. 12:265-268
RNA polymerase activity was measured in isolated cardiac nuclei subjected to hydrostatic pressure. After 20 min of pressure, Mn2+ stimulated RNA polymerase II activity was increased. The response to pressure was inhibited by low concentrations of alp
Publikováno v:
Alcoholism: Clinical and Experimental Research. 8:54-61
Although acute perfusion of guinea pig hearts with ethanol does not affect cardiac protein synthesis, the latter is inhibited after prolonged ingestion of ethanol when tested in an in vitro system with the working right ventricle. This study reports
Publikováno v:
Gastroenterology. 71:214-220
Elevated levels of serum albumin have been noted in patients on chronic methadone maintenance and in heroin addicts. This observation was investigated in rabbits maintained on daily methadone 4 mg per kg of body weight after a period of 3 months on i
Publikováno v:
Gastroenterology. 80:159-165
The effect of ethanol on the secretion of proteins was studied in hepatocytes isolated from 24-h fasted rats and from fed rats. Hepatocytes were isolated after collagenase disruption of the liver and incubated in a standard medium containing amino ac
Publikováno v:
Gastroenterology. 74:672-676
The effects of ethanol, 4-methylpyrazole (4-MP), and acetaldehyde on albumin and urea synthesis, and on polysome aggregation were studied in isolated perfused rabbit livers. Fed or fasted males served as donors and the perfusate contained ethanol, 20
Publikováno v:
Gastroenterology. 71:123-127
The isolated perfused rabbit liver was used to compare the acute effects of alcohol and amino acids on albumin synthesis, polysomal aggregation, and RNA turnover. The perfusion solutions were modified to contain test amino acids in a final concentrat