Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Sidney S. Mirvish"'
Publikováno v:
Chemical Research in Toxicology
Nitrite-treated meat is a reported risk factor for colon cancer. Mice that ingested sodium nitrite (NaNO2) or hot dogs (a nitrite-treated product) showed increased fecal excretion of apparent N-nitroso compounds (ANC). Here, we investigated for the f
Autor:
Lin Zhou, Karen L. Pennington, Sidney S. Mirvish, James L. Wisecarver, Muhammad Zahid, Samuel M. Cohen, Muhammad M. Anwar, Valerie Shostrom
Publikováno v:
Nutrition and cancer. 68(1)
A reported linkage between processed (nitrite-treated) meat products and the incidence of colon cancer could be due to sodium nitrite (NaNO2) itself or to N-nitroso compounds produced from the nitrite. Exposure to nitrite occurs due to residual nitri
Publikováno v:
Chemical Research in Toxicology. 21:2344-2351
It was proposed that colon cancer induced by red and nitrite-preserved meat is due to meat-derived N-nitroso compounds in the colonic contents. To explore this view, we previously showed that feeding beef and hot dogs increased the fecal output of to
Publikováno v:
American Journal of Public Health. 96:1934-1939
Harm reduction strategies involve promoting a product that has adverse health consequences as a substitute for one that has more severe adverse health consequences. Smokeless tobacco low in nitrosamine content offers potential benefits in reducing sm
Autor:
Fulvio Perini, Steven G. Carmella, James Haorah, Lin Zhou, Sidney S. Mirvish, Takayuki Shibamoto
Publikováno v:
Journal of Agricultural and Food Chemistry. 54:5679-5687
Hot dogs contain apparent N-nitroso compounds (ANC) and ANC precursors (ANCP). ANCP purification was followed by nitrosation, sulfamic acid treatment, and analysis for ANC. Aqueous hot dog extracts were adsorbed on silica gel, which was eluted with M
Publikováno v:
Journal of Agricultural and Food Chemistry. 49:6068-6078
Total N-nitroso compounds (NOC) and NOC precursors (NOCP) were determined in extracts of food and tobacco products. Following Walters' method, NOC were decomposed to NO with refluxing HBr/HCl/HOAc/EtOAc and NO was measured by chemiluminescence. NOC w
Autor:
Sandra M. Wells, Michael J. Breitbach, Martha Rhoades, Sidney S. Mirvish, Patrick J. Shea, Gregory D. Bennett, Nikita Joshi
Publikováno v:
Journal of toxicology and environmental health. Part A. 76(17)
Nitrate and atrazine (ATR) occur in combination in some drinking-water supplies and might react to form N-nitrosoatrazine (NNAT), which is reportedly more toxic than nitrate, nitrite, or ATR. Current evidence from population-based studies indicates t
Autor:
K J Reimers, A C Grandjean, B Kutler, Sidney S. Mirvish, E R Lyden, C R Morris, J Haorah, S C Chen
Publikováno v:
European Journal of Cancer Prevention. 9:335-342
Salivary nitrite arises from nitrate and is the main source of gastric nitrite, a precursor of carcinogenic N-nitroso compounds. We examined nitrate and nitrite levels in unstimulated saliva from subjects consuming low-nitrate low-vitamin C diets. Wh
Publikováno v:
International Journal of Gastrointestinal Cancer. 27:105-112
The mechanism whereby methyl-2-oxopropylnitrosamine (MOP) is activated remains unknown. To begin investigating this mechanism, we followed MOP disappearance during its incubation with liver and pancreatic slices and homogenates from Syrian hamsters a
Autor:
Yoshinori Yamashita, Thomas C. Smyrk, Ronald A. Hinder, Thomas E. Adrian, Geoffery W.B. Clark, Tom R. DeMeester, Sidney S. Mirvish, Norio Kako, Kiichi Homma
Publikováno v:
Journal of Gastrointestinal Surgery. 2:350-355
When duodenal content is allowed to reflux into the esophagus of nitrosamine-treated rats, esophageal cancer is induced more rapidly and at higher frequency than after carcinogen treatment alone. The purpose of the present study was to identify the c