Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Sidney Leskowitz"'
Publikováno v:
European Journal of Immunology. 20:587-593
We have compared by functional assays the relative preference among Ia molecules for their ability to present tyrosine-azobenzenearsonate (ABA-Tyr) to T cells. Immunization of B10.BR mice (IAk, IEk) with ABA-Tyr resulted in the induction of IAk-restr
Publikováno v:
Cellular Immunology. 125:518-525
Although tyrosine-azobenzenearsonate (ABA-Tyr) is not degraded by proteolytic enzymes, its presentation by accessory cells is inhibited by lysosomotropic agents such as chloroquine. Presentation of ABA-poly-L-glutamic, alanine, tyrosine (ABA-GAT) is
Publikováno v:
Molecular Immunology. 27:79-86
The T cell response to l -tyrosine-azobenzenearsonate (ABA-tyr) has been studied using T cell lines and clones derived from three different mouse strains, B10.BR, B10.A (5R) and C57B1/6. In all cases, the arsonate group in conjunction with the amino
Autor:
Sidney Leskowitz, Syamal Roy
Publikováno v:
Molecular Immunology. 21:1031-1036
The ability of various analogues of tyrosine-azobenzenearsonate (ABA-tyr) to elicit responses in CBA mice and Lewis rats was studied in order to determine the essential features for association with Ia molecules on accessory cells and T-cell recognit
Publikováno v:
The Journal of Immunology. 115:1409-1413
In this study we have investigated the role played by the mode of attachment of the hapten on autologous IgG in the induction of carrier-determined tolerance. Three conjugates of the dinitrophenyl hapten and mouse γ-globulin were prepared: 1) DNP-ɛ
Publikováno v:
Cellular Immunology. 47:407-415
BALB/c and DBA/2 mice differ with respect to ease of tolerance induction with HGG, BALB/c mice being the resistant strain. When tested for susceptibility to tolerance induction with individual IgG subclasses, both strains were easily rendered unrespo
Autor:
Miguel J. Stadecker, Sidney Leskowitz
Publikováno v:
The Journal of Immunology. 116:1646-1651
Systemic treatment with a heterologous anti-T cell serum of guinea pigs immunized with EA in IFA markedly suppressed CBH reactivity to specific antigen and T cell mitogens, as judged by gross reactivity, histology, and skin histamine. The antiserum p
Publikováno v:
Microbiology and Immunology. 26:853-869
Immunization of Lewis rats with azobenzenearsonate-N-acetyl-L-tyrosine (ABA-tyr) in complete Freund's adjuvant (CFA), produces a hapten-specific helper T cell response measured by an increase in plaque forming cells (PFC) against a different hapten.
Autor:
Suraj B. Singh, Sidney Leskowitz
Publikováno v:
The Journal of Immunology. 120:734-738
A lipid conjugate of BSA was made by coupling dodecylamine to the COOH groups of BSA (DA-BSA). Studies on the immunogenicity of this material and one made by coupling dodecanoic anhydride to NH2 groups (D-BSA) demonstrated that cell-mediated immunity
Autor:
Miodrag L. Lukic, Sidney Leskowitz
Publikováno v:
Experimental Biology and Medicine. 148:420-423
The “hot-pulse suicide” technique was first applied to lymphoid cells by Dutton and Mishell (1). The objective of this technique is to kill replicating cells in vitro by having them incorporate radioactive components such as thymidine, thereby el