Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Sidney B. Cambridge"'
Autor:
Sidney B. Cambridge
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract Background Little is known why proteins and RNAs exhibit half-lives varying over several magnitudes. Despite many efforts, a conclusive link between half-lives and gene function could not be established suggesting that other determinants may
Externí odkaz:
https://doaj.org/article/f21ac7044a004ce4ae59b47d24164db7
Autor:
Alessio Attardo, Sidney B Cambridge
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 2, Pp 401-402 (2024)
Externí odkaz:
https://doaj.org/article/d2042b7074d84ffdba86c0532ea57d55
SummaryGenetic engineering of quintuple transgenic brain tissue was used to establish a low background, Cre-dependent version of the inducible Tet-On system for fast, cell type-specific transgene expression in vivo. Co-expression of a constitutive, C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67387b2dcf543177ccb8b7aa4d560515
https://doi.org/10.1101/2021.01.13.426508
https://doi.org/10.1101/2021.01.13.426508
Publikováno v:
ChemBioChem. 19:1341-1348
We report the synthesis and photolytic properties of caged 9-aminodoxycycline derivatives modified with 2-{4'-bis-[2-(2methoxyethoxy)ethyl]-4-nitrobiphenyl-3-yl}prop-1-oxy (EANBP) and PEG7-ylated (7-diethylamino-2-oxo-2H-chromen-4-yl)methyl (PEG7-DEA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e926fc84611c97f4b17d8b898cc54221
https://doi.org/10.1002/cbic.201700628
https://doi.org/10.1002/cbic.201700628
Acute alcohol intoxication is frequently observed in modern societies and carries a vast burden, ranging from traffic accidents to transient memory loss. Despite years of intense research, the effects of acute ethanol intoxication on brain function r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe8c98ff66a0ba0f2e681cd4fabf654
https://doi.org/10.1101/536334
https://doi.org/10.1101/536334
Autor:
Michael Bartolf-Kopp, Markus Hecker, Mihnea C. Trache, Sidney B. Cambridge, Nina D. Ullrich, Valentin Sottas, Carl-Mattheis Wahl
Publikováno v:
Journal of molecular and cellular cardiology. 120
The therapeutic potential of induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) is limited by immature functional features including low impulse propagation and reduced cell excitability. Key players regulating electrical activity are vo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49dc951e75719c46677e651015841f9c
https://pubmed.ncbi.nlm.nih.gov/29777691
https://pubmed.ncbi.nlm.nih.gov/29777691
Autor:
Frank Bradke, Chuong Nguyen, Sabine Wegehingel, Sidney B. Cambridge, Walter Nickel, Michael Stiess
Publikováno v:
Journal of proteome research 14(8), 3229-3238 (2015). doi:10.1021/acs.jproteome.5b00199
Recent evidence suggests that the extracellular protein milieu is much more complex than previously assumed as various secretome analyses from different cell types described the release of hundreds to thousands of proteins. The extracellular function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77b30b3b2b5b0a1fb6a6937c29fc4b10
https://doi.org/10.1021/acs.jproteome.5b00199
https://doi.org/10.1021/acs.jproteome.5b00199
Autor:
Christian Schultz, Heinz Beck, Christian Thome, Tony Kelly, Antonio Yanez, Maren Engelhardt, Alexei V. Egorov, Martin Both, Andreas Draguhn, Sidney B. Cambridge
Publikováno v:
Neuron. 83(6):1418-1430
SummaryNeuronal processing is classically conceptualized as dendritic input, somatic integration, and axonal output. The axon initial segment, the proposed site of action potential generation, usually emanates directly from the soma. However, we foun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39ab4cdd73259a00ea413ce6c982ddd6
Autor:
Volker Hagen, Tobias Bonhoeffer, Sidney B. Cambridge, Daniel Geissler, A. Francis Stewart, Mazahir T. Hasan, Federico Calegari, Konstantinos Anastassiadis, Wieland B. Huttner
Publikováno v:
Nature methods
High spatial and temporal resolution of conditional gene expression is typically difficult to achieve in whole tissues or organisms. We synthesized two reversibly inhibited, photoactivatable (‘caged’) doxycycline derivatives with different membra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b542b1f18b5ae6bf7531b721d9f5da1
https://doi.org/10.1038/nmeth.1340
https://doi.org/10.1038/nmeth.1340
Publikováno v:
ResearcherID
Dendritic spines on pyramidal neurons receive the vast majority of excitatory input and are considered electrobiochemical processing units, integrating and compartmentalizing synaptic input. Following synaptic plasticity, spines can undergo morpholog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab8dba23852f9d1729de5a25e1acb78c