Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Sidney B. Auerbach"'
Autor:
Gongliang Zhang, Swapna Krishnamoorthy, Sidney B. Auerbach, Jianning Wei, Zhiyuan Ma, Rui Tao
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 107:830-841
Previous studies have demonstrated that serotonin (5-HT) syndromes, particularly for the malignant cases, can be alleviated by ice water mists, cooling blankets and many other external cooling measures. In this study, we tested the hypothesis that ex
Publikováno v:
Neuroscience. 147:106-116
Similar to kappa-opioids, nociceptin/orphanin FQ (OFQ) exerts anti-mu-opioid actions. This may involve interactions within the circuitry controlling 5-HT neurons in the dorsal raphe nucleus (DRN) that project to the nucleus accumbens (NAcc). To test
Publikováno v:
British Journal of Pharmacology. 139:1498-1504
Fentanyl is a μ-opioid analgesic that might disinhibit 5-HT neurons and thus increase 5-HT efflux. However, fentanyl also binds to 5-HT1A receptors, and if it activates 5-HT1A somatodendritic autoreceptors, the resultant inhibition might offset opio
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 367:297-305
Some clinical reports suggest that tricyclic antidepressants which block both noradrenaline and serotonin (5-HT) reuptake (SNRIs) are more effective than selective 5-HT reuptake inhibitors (SSRIs) in treating severe depression. Moreover, one neuroche
Autor:
Rui Tao, Sidney B. Auerbach
Publikováno v:
Journal of Neurochemistry. 63:517-524
The effect of morphine on serotonin (5-HT) and 5-hydroxyindoleacetic acid (5-HIAA) in the CNS of unanesthetized rats was investigated by microdialysis. Morphine was administered either subcutaneously, by local perfusion into the diencephalon, or by i
Autor:
Rui Tao, Sidney B. Auerbach
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 303:704-710
To characterize the effects of morphine on serotonin (5-HT) in the central nervous system, we used microdialysis in freely behaving rats. Subcutaneous injection of morphine sulfate produced a dose-dependent increase in extracellular 5-HT in the dorsa
Autor:
Sidney B. Auerbach, Rui Tao
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 303:549-556
Opioid receptor subtypes may have site-specific effects and play different roles in modulating serotonergic neurotransmission in the mammalian central nervous system. To test this hypothesis, we used in vivo microdialysis to measure changes in extrac
Publikováno v:
European Journal of Pharmacology. 445:69-81
Hypothalamic 5-HT (serotonin) regulates food intake, energy expenditure and bodyweight. Using in vivo microdialysis, we determined the effects of various anorectic drugs on hypothalamic extracellular 5-HT levels during the dark phase when rats predom
Publikováno v:
British Journal of Pharmacology. 121:1707-1715
1 The regulation of 5-hydroxytryptamine (5-HT) release by excitatory amino acid (EAA) receptors was examined by use of microdialysis in the CNS of freely behaving rats. Extracellular 5-HT was measured in the dorsal raphe nucleus (DRN), median raphe n
Publikováno v:
Neuropharmacology. 36:475-482
The effect of repeated administration of the reuptake inhibitor citalopram (10 mg/kg s.c., b.i.d. for 14 days) or saline on extracellular 5-hydroxytryptamine (5-HT) and autoreceptor sensitivity was assessed using microdialysis in the frontal cortex (