Zobrazeno 1 - 10
of 247
pro vyhledávání: '"Sidney, Santos"'
Autor:
Polyanna Oliveira, Paula Correa, Angelina Acosta, Juliana Freitas, Taísa Machado-Lopes, Thais Bomfim-Palma, Ândrea Ribeiro-dos-Santos, Sidney Santos, Roberto Nascimento, Ivana Nascimento, Kiyoko Abe-Sandes
Publikováno v:
Global Medical Genetics, Vol 10, Iss 04, Pp 376-381 (2023)
Introduction Cancer is a multifactorial disease dependent on the influence of genetic and environmental factors. About 10% of cancers are associated with germline mutations, which predispose to a higher risk of developing cancer. Currently, the use o
Externí odkaz:
https://doaj.org/article/07e37ab30a0f4284b513e8a1b03b0848
Autor:
Roberta B. Andrade, Giovanna C. Cavalcante, Marcos A. T. Amador, Fabiano Cordeiro Moreira, André S. Khayat, Paulo P. Assumpção, Ândrea Ribeiro-dos-Santos, Ney P. C. Santos, Sidney Santos
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 5, Pp 2275-2286 (2022)
Cancer is a multifactorial group of diseases, being highly incident and one of the leading causes of death worldwide. In Brazil, there is a great variation in cancer incidence and impact among the different geographic regions, partly due to the genet
Externí odkaz:
https://doaj.org/article/f1b4ee307ee44031839adca5914ef344
Autor:
Amanda Ferreira Vidal, Rafaella Sousa Ferraz, Antonette El-Husny, Caio Santos Silva, Tatiana Vinasco-Sandoval, Leandro Magalhães, Milene Raiol-Moraes, Williams Fernandes Barra, Cynthia Lara Brito Lins Pereira, Paulo Pimentel de Assumpção, Leonardo Miranda de Brito, Ricardo Assunção Vialle, Sidney Santos, Ândrea Ribeiro-dos-Santos, André M. Ribeiro-dos-Santos
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-8 (2021)
Abstract Background Next generation sequencing (NGS) has been a handy tool in clinical practice, mainly due to its efficiency and cost-effectiveness. It has been widely used in genetic diagnosis of several inherited diseases, and, in clinical oncolog
Externí odkaz:
https://doaj.org/article/8f815626122642838232d85a9b8cb17a
Autor:
Inácio Gomes Medeiros, André Salim Khayat, Beatriz Stransky, Sidney Santos, Paulo Assumpção, Jorge Estefano Santana de Souza
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Coronavirus disease 2019 (COVID-19) rapidly transformed into a global pandemic, for which a demand for developing antivirals capable of targeting the SARS-CoV-2 RNA genome and blocking the activity of its genes has emerged. In this work, we
Externí odkaz:
https://doaj.org/article/1a663b27ce7543848093e72d4b52ae2f
Autor:
Larissa B. Reis, Renato M. Bakos, Fernanda S. L. Vianna, Gabriel S. Macedo, Vanessa C. Jacovas, André M. Ribeiro-dos-Santos, Sidney Santos, Lúcio Bakos, Patricia Ashton-Prolla
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background Melanoma is the most aggressive type of skin cancer and is associated with environmental and genetic risk factors. It originates in melanocytes, the pigment-producing cells. Single nucleotide polymorphisms (SNPs) in pigmentation g
Externí odkaz:
https://doaj.org/article/3126b9b528a5470591334d4b6ca6c196
Autor:
Giovanna Chaves Cavalcante, Milene Raiol de Moraes, Cristina Maria Duarte Valente, Caio Santos Silva, Antônio André Conde Modesto, Paula Baraúna de Assumpção, Paulo Pimentel de Assumpção, Sidney Santos, Ândrea Ribeiro-dos-Santos
Publikováno v:
BMC Medical Genetics, Vol 21, Iss 1, Pp 1-6 (2020)
Abstract Background Apoptosis is a type of cell death involved in different pathways inherent to the cell and the evasion from this mechanism has been related to cancer, although this process remains not very well comprehended. Gastric cancer (GC) is
Externí odkaz:
https://doaj.org/article/e8d1f16d9e7f485a85443aa68c0203ce
Autor:
Ana Paula Schaan, Leonor Gusmão, Juliana Jannuzzi, Antonio Modesto, Marcos Amador, Diego Marques, Silvia Helena Rabenhorst, Raquel Montenegro, Thayson Lopes, France Keiko Yoshioka, Giovanny Pinto, Sidney Santos, Lorenna Costa, Vivian Silbiger, Ândrea Ribeiro-dos-Santos
Publikováno v:
BMC Evolutionary Biology, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background The current Brazilian population is the product of centuries of admixture between intercontinental founding groups. Although previous results have revealed a heterogeneous distribution of mitochondrial lineages in the Northeast re
Externí odkaz:
https://doaj.org/article/c24ce316c14f4242864c5a795778c695
Autor:
Paola Fazzi-Gomes, Jonas Aguiar, Gleyce Fonseca Cabral, Diego Marques, Helber Palheta, Fabiano Moreira, Marilia Rodrigues, Renata Cavalcante, Jorge Souza, Caio Silva, Igor Hamoy, Sidney Santos
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0240002 (2021)
A broad panel of potentially amplifiable microsatellite loci and a multiplex system were developed for the Amazonian symbol fish species Arapaima gigas, which is currently in high danger of extinction due to the disorderly fishing exploitation. Sever
Externí odkaz:
https://doaj.org/article/0496c839065b45a48a312a955992d6dc
Autor:
André M. Ribeiro-dos-Santos, Amanda Ferreira Vidal, Tatiana Vinasco-Sandoval, João Guerreiro, Sidney Santos, Ândrea Ribeiro-dos-Santos, Sandro J. de Souza
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Studies on the peopling of South America have been limited by the paucity of sequence data from Native Americans, especially from the east part of the Amazon region. Here, we investigate the whole exome variation from 58 Native American individuals (
Externí odkaz:
https://doaj.org/article/d750eb5631f042679cdf2c1b2b722803
Autor:
Juliana Carla Gomes Rodrigues, Tatiane Piedade de Souza, Lucas Favacho Pastana, André Maurício Ribeiro Dos Santos, Marianne Rodrigues Fernandes, Pablo Pinto, Alayde Vieira Wanderley, Sandro José de Souza, José Eduardo Kroll, Adenilson Leão Pereira, Leandro Magalhães, Laís Reis das Mercês, Amanda Ferreira Vidal, Tatiana Vinasco-Sandoval, Giovanna Chaves Cavalcante, João Farias Guerreiro, Paulo Pimentel de Assumpção, Ândrea Ribeiro-Dos-Santos, Sidney Santos, Ney Pereira Carneiro Dos Santos
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231651 (2020)
IntroductionThe nudix hydrolase 15 (NUDT15) gene acts in the metabolism of thiopurine, by catabolizing its active metabolite thioguanosine triphosphate into its inactivated form, thioguanosine monophosphate. The frequency of alternative NUDT15 allele
Externí odkaz:
https://doaj.org/article/80247432adae42ae8572c23f313d6aa1