Analysis of amyotrophic lateral sclerosis as a multistep process: a population-based modelling study.

Autor: Al-Chalabi A; King's College London, Institute of Psychiatry, Department of Clinical Neuroscience, London, UK. Electronic address: ammar.al-chalabi@kcl.ac.uk., Calvo A; ALS Center, Rita Levi Montalcini Department of Neuroscience, University of Turin, Turin, Italy; Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Turin, Italy; Neuroscience Institute of Turin (NIT), Turin, Italy., Chio A; ALS Center, Rita Levi Montalcini Department of Neuroscience, University of Turin, Turin, Italy; Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Turin, Italy; Neuroscience Institute of Turin (NIT), Turin, Italy., Colville S; Euan MacDonald Centre for MND Research, University of Edinburgh, Edinburgh, UK., Ellis CM; Motor Nerve Clinic, King's College Hospital, London, UK., Hardiman O; Academic Unit of Neurology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Heverin M; Academic Unit of Neurology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Howard RS; Department of Clinical Neuroscience, UCL Institute of Neurology, London, UK; National Hospital for Neurology and Neurosurgery, London, UK., Huisman MHB; Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands., Keren N; King's College London, Institute of Psychiatry, Department of Clinical Neuroscience, London, UK., Leigh PN; Department of Neurology, Brighton and Sussex Medical School Trafford Centre for Biomedical Research, University of Sussex, Falmer, East Sussex, UK., Mazzini L; Department of Neurology, 'Amedeo Avogadro' University of Eastern Piedmont and Azienda Ospedaliera Universitaria Maggiore della Carità, Novara, Italy., Mora G; Salvatore Maugeri Foundation, IRCSS; Scientific Institute of Milan, Milan, Italy., Orrell RW; Department of Clinical Neuroscience, UCL Institute of Neurology, London, UK; National Hospital for Neurology and Neurosurgery, London, UK., Rooney J; Academic Unit of Neurology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Scott KM; Department of Neurology, Addenbrooke's Hospital, Cambridge, UK., Scotton WJ; King's College London, Institute of Psychiatry, Department of Clinical Neuroscience, London, UK., Seelen M; Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands., Shaw CE; King's College London, Institute of Psychiatry, Department of Clinical Neuroscience, London, UK., Sidle KS; Department of Clinical Neuroscience, UCL Institute of Neurology, London, UK; National Hospital for Neurology and Neurosurgery, London, UK., Swingler R; Euan MacDonald Centre for MND Research, University of Edinburgh, Edinburgh, UK., Tsuda M; King's College London, Institute of Psychiatry, Department of Clinical Neuroscience, London, UK., Veldink JH; Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands., Visser AE; Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands., van den Berg LH; Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands., Pearce N; Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK; Centre for Public Health Research, Massey University Wellington Campus, Wellington, New Zealand.

Publikováno v: The Lancet. Neurology [Lancet Neurol] 2014 Nov; Vol. 13 (11), pp. 1108-1113. Date of Electronic Publication: 2014 Oct 07.