Proteasomal inhibition preferentially stimulates lysosome activity relative to autophagic flux in primary astrocytes.

Autor: Yuan R; Department of Neuroscience, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Hahn Y; Department of Neuroscience, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Stempel MH; Department of Neuroscience, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Sidibe DK; Department of Neuroscience, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Laxton O; Department of Neuroscience, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Chen J; Department of Neuroscience, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Kulkarni A; Department of Neuroscience, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Maday S; Department of Neuroscience, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

Publikováno v: Autophagy [Autophagy] 2023 Feb; Vol. 19 (2), pp. 570-596. Date of Electronic Publication: 2022 Jun 19.

Retrograde Axonal Autophagy and Endocytic Pathways Are Parallel and Separate in Neurons.

Autor: Kulkarni VV; Department of Neuroscience, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104., Stempel MH; Department of Neuroscience, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104., Anand A; Department of Neuroscience, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104., Sidibe DK; Department of Neuroscience, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104., Maday S; Department of Neuroscience, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104 smaday@pennmedicine.upenn.edu.

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2022 Nov 09; Vol. 42 (45), pp. 8524-8541. Date of Electronic Publication: 2022 Sep 27.

A robust Pax7EGFP mouse that enables the visualization of dynamic behaviors of muscle stem cells.

Autor: Tichy ED; Department of Orthopaedic Surgery, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, PA, USA., Sidibe DK; Department of Orthopaedic Surgery, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, PA, USA., Greer CD; Department of Orthopaedic Surgery, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, PA, USA.; Cell and Molecular Biology Graduate Program, The University of Pennsylvania, Philadelphia, PA, USA., Oyster NM; Department of Orthopaedic Surgery, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, PA, USA., Rompolas P; Cell and Molecular Biology Graduate Program, The University of Pennsylvania, Philadelphia, PA, USA.; Department of Dermatology, Institute for Regenerative Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Rosenthal NA; The Jackson Laboratory, Bar Harbor, ME, USA.; Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, MA, USA.; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.; Australian Regenerative Medicine Institute, Monash University, Melbourne, VIC, Australia.; National Heart and Lung Institute, Imperial College London, London, UK., Blau HM; Baxter Laboratory for Stem Cell Biology, Department of Microbiology and Immunology, Institute for Stem Cell Biology and Regenerative Medicine, Stanford School of Medicine, Stanford, CA, USA., Mourkioti F; Department of Orthopaedic Surgery, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, PA, USA. fmour@pennmedicine.upenn.edu.; Cell and Molecular Biology Graduate Program, The University of Pennsylvania, Philadelphia, PA, USA. fmour@pennmedicine.upenn.edu.; Department of Cell and Developmental Biology, Penn Institute of Regenerative Medicine, Musculoskeletal Regeneration Program, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, PA, USA. fmour@pennmedicine.upenn.edu.; Musculoskeletal Regeneration Program, Department of Orthopaedic Surgery and Cell and Developmental Biology, Penn Institute of Regenerative Medicine, The University of Pennsylvania, 3450 Hamilton Walk, 112A Stemmler Hall, Philadelphia, PA, 19104-6081, USA. fmour@pennmedicine.upenn.edu.

Publikováno v: Skeletal muscle [Skelet Muscle] 2018 Aug 24; Vol. 8 (1), pp. 27. Date of Electronic Publication: 2018 Aug 24.

Single Stem Cell Imaging and Analysis Reveals Telomere Length Differences in Diseased Human and Mouse Skeletal Muscles.

Autor: Tichy ED; Department of Orthopaedic Surgery, Perelman School of Medicine, The University of Pennsylvania, 112A Stemmler Hall, 3450 Hamilton Walk, Philadelphia, PA 19104-6081, USA., Sidibe DK; Department of Orthopaedic Surgery, Perelman School of Medicine, The University of Pennsylvania, 112A Stemmler Hall, 3450 Hamilton Walk, Philadelphia, PA 19104-6081, USA., Tierney MT; Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA., Stec MJ; Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA., Sharifi-Sanjani M; Department of Orthopaedic Surgery, Perelman School of Medicine, The University of Pennsylvania, 112A Stemmler Hall, 3450 Hamilton Walk, Philadelphia, PA 19104-6081, USA., Hosalkar H; Joint Preservation Center, Tricity Medical Center, Joint Preservation & Deformity Correction Center & Traumatic Brain Injury Program, Paradise Valley Hospital, National City, CA 91950, USA., Mubarak S; Department of Orthopedic Surgery, Rady Children's Hospital, 3030 Children's Way, San Diego, CA 92123, USA., Johnson FB; Department of Pathology and Laboratory Medicine, Institute on Aging, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Sacco A; Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA., Mourkioti F; Department of Orthopaedic Surgery, Perelman School of Medicine, The University of Pennsylvania, 112A Stemmler Hall, 3450 Hamilton Walk, Philadelphia, PA 19104-6081, USA; Department of Cell and Developmental Biology, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: fmour@mail.med.upenn.edu.

Publikováno v: Stem cell reports [Stem Cell Reports] 2017 Oct 10; Vol. 9 (4), pp. 1328-1341. Date of Electronic Publication: 2017 Sep 07.

Overlapping functions of SIX homeoproteins during embryonic myogenesis.

Autor: Wurmser, Maud¹ (AUTHOR), Madani, Rouba¹ (AUTHOR), Chaverot, Nathalie¹ (AUTHOR), Backer, Stéphanie¹ (AUTHOR), Borok, Matthew² (AUTHOR), Dos Santos, Matthieu¹ (AUTHOR), Comai, Glenda^3,4 (AUTHOR), Tajbakhsh, Shahragim^3,4 (AUTHOR), Relaix, Frédéric² (AUTHOR), Santolini, Marc⁵ (AUTHOR), Sambasivan, Ramkumar⁶ (AUTHOR), Jiang, Rulang^7,8 (AUTHOR), Maire, Pascal¹ (AUTHOR) pascal.maire@inserm.fr

Publikováno v: PLoS Genetics. 6/2/2023, Vol. 19 Issue 6, p1-28. 28p.