Telomere regulation during ageing and tumorigenesis of the grey mouse lemur

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An Acyclic Oligoheteroaryle That Discriminates Strongly between Diverse G-Quadruplex Topologies

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Publikováno v: Angewandte Chemie International Edition
Angewandte Chemie International Edition, 2011, 50 (37), pp.8745-8749. ⟨10.1002/anie.201103422⟩
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2011, 50 (37), pp.8745-8749. ⟨10.1002/anie.201103422⟩

These synthetic ligands should fulfill an essentialrequirement to enable correlating their in cellulo biologicaleffects to their quadruplex recognition ability, namely strongspecificity for the targeted quadruplex combined with poorassociation to dup

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https://hal.science/hal-02125709/document

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The G-Quadruplex Ligand Telomestatin Impairs Binding of Topoisomerase IIlα to G-Quadruplex-Forming Oligonucleotides and Uncaps Telomeres in ALT Cells.

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Publikováno v: PLoS ONE; 2009, Vol. 4 Issue 9, p1-14, 14p, 3 Color Photographs, 4 Diagrams, 4 Graphs