Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Sidhartha R. Sinha"'
Autor:
Chiraag Kulkarni, Derek Liu, Touran Fardeen, Eliza Rose Dickson, Hyunsu Jang, Sidhartha R. Sinha, John Gubatan
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 17 (2024)
Interest in artificial intelligence (AI) applications for ulcerative colitis (UC) has grown tremendously in recent years. In the past 5 years, there have been over 80 studies focused on machine learning (ML) tools to address a wide range of clinical
Externí odkaz:
https://doaj.org/article/37834f4b285845a9932625fc2b2190a1
Autor:
Gulshan Singh, Hassan Brim, Yeneneh Haileselassie, Sudhir Varma, Aida Habtezion, Mudasir Rashid, Sidhartha R. Sinha, Hassan Ashktorab
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 7, Pp 5558-5574 (2023)
Despite the existence of effective drugs used to treat inflammatory bowel disease (IBD), many patients fail to respond or lose response over time. Further, many drugs can carry serious adverse effects, including increased risk of infections and malig
Externí odkaz:
https://doaj.org/article/5ca68026f49b44e8a2d7781697190a34
Autor:
John Gubatan, Chiraag V. Kulkarni, Sarah Melissa Talamantes, Michelle Temby, Touran Fardeen, Sidhartha R. Sinha
Publikováno v:
Nutrients, Vol 15, Iss 3, p 579 (2023)
Diet is intimately linked to the gastrointestinal (GI) tract and has potent effects on intestinal immune homeostasis. Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the GI tract. The therapeutic implications of diet in p
Externí odkaz:
https://doaj.org/article/e94181c959e6436db2321de8974eb4be
Autor:
Samuel J. S. Rubin, Lawrence Bai, Yeneneh Haileselassie, Gotzone Garay, Chohee Yun, Laren Becker, Sarah E. Streett, Sidhartha R. Sinha, Aida Habtezion
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Distinguishing clinical subtypes of IBD is critical for optimal treatments, outcome prediction, and better understanding of disease pathogenesis. Here the authors phenotype blood and intestinal immune cells by mass cytometry and identify signatures a
Externí odkaz:
https://doaj.org/article/9a229a7519d7425b9121ac0a514fa771
Autor:
John Gubatan, Theresa Louise Boye, Michelle Temby, Raoul S. Sojwal, Derek R. Holman, Sidhartha R. Sinha, Stephan R. Rogalla, Ole Haagen Nielsen
Publikováno v:
Microorganisms, Vol 10, Iss 7, p 1371 (2022)
The gut microbiome has increasingly been recognized as a critical and central factor in inflammatory bowel disease (IBD). Here, we review specific microorganisms that have been suggested to play a role in the pathogenesis of IBD and the current state
Externí odkaz:
https://doaj.org/article/76bf4c6a9f714a46adc7b40019cc28e5
Autor:
Suhrid Banskota, Hassan Brim, Yun Han Kwon, Gulshan Singh, Sidhartha R. Sinha, Huaqing Wang, Waliul I. Khan, Hassan Ashktorab
Publikováno v:
Molecules, Vol 26, Iss 11, p 3351 (2021)
Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal tract with an incompletely understood pathogenesis. Long-standing colitis is associated with increased risk of colon cancer. Despite the availability of vari
Externí odkaz:
https://doaj.org/article/f834c48e544843468f7cda3b7ca7db10
Autor:
Yan Jiang, Karolin Jarr, Cosima Layton, Christopher D. Gardner, Judith F. Ashouri, Maria T. Abreu, Sidhartha R. Sinha
Publikováno v:
Nutrients, Vol 13, Iss 3, p 890 (2021)
Despite being a focal issue to patients, the effect of diet on adult inflammatory bowel disease (IBD) remains underexplored with limited guidance. While promising clinical trials are currently underway, there is a need for further evidence-based reco
Externí odkaz:
https://doaj.org/article/7817976ccba3454f9c1631a4acbbe85c
Autor:
Priyanka Jadhav, Yan Jiang, Karolin Jarr, Cosima Layton, Judith F. Ashouri, Sidhartha R. Sinha
Publikováno v:
Nutrients, Vol 12, Iss 7, p 2156 (2020)
The microbiome is an important contributor to a variety of fundamental aspects of human health, including host metabolism, infection, and the immune response. Gut dysbiosis has been identified as a contributor to the errant immune response in a varie
Externí odkaz:
https://doaj.org/article/f127f027de18461c9163469d0dfee582
Autor:
Ashktorab, Gulshan Singh, Hassan Brim, Yeneneh Haileselassie, Sudhir Varma, Aida Habtezion, Mudasir Rashid, Sidhartha R. Sinha, Hassan
Publikováno v:
Current Issues in Molecular Biology; Volume 45; Issue 7; Pages: 5558-5574
Despite the existence of effective drugs used to treat inflammatory bowel disease (IBD), many patients fail to respond or lose response over time. Further, many drugs can carry serious adverse effects, including increased risk of infections and malig
Autor:
Cyrus A Buckman, Jenny Wang, Sidhartha R. Sinha, Kian Keyashian, Samuel J S Rubin, John Gubatan
Publikováno v:
Clinical and Experimental Gastroenterology
Leukocyte trafficking to the gastrointestinal tract is recognized to play a role in the pathogenesis of inflammatory bowel disease (IBD). Integrins are expressed on immune cells and interact with cell adhesion molecules (CAM) to mediate leukocyte tra