Výsledky vyhledávání - "Sidharth S Jha"

Comparative Analysis of Induced CD4+ Tregs (Itreg) In Response to CD8+ CTL Induction From PBL By MHC-I Bound Mart-1 Peptide Pulsed DC or Autologous Tumor Cells with Freshly Isolated TIL from Human Melanoma

Autor: Sidharth S Jha, Upendra P. Hegde, Nitya G. Chakraborty

Publikováno v: Journal of Clinical Research in Dermatology. 3:1-11

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a52687653aad3c9c54afb5fe93829945
https://doi.org/10.15226/2378-1726/3/4/00133

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Knockdown of T-bet expression in Mart-127–35-specific T-cell-receptor-engineered human CD4+ CD25− and CD8+ T cells attenuates effector function

Autor: David I. Dorsky, Sidharth S Jha, Nitya G. Chakraborty, Prashant Singh, Bijay Mukherji

Gene transfer to create tumour epitope-specific cytolytic T cells for adoptive immunotherapy of cancer remains an area of active inquiry. When the Mart-127-35 -specific DMF5 T-cell receptor (TCR) is transferred into peripheral human CD4(+) T cells, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4528e6e3fa7b6353f315b1cfbc7d335a
https://europepmc.org/articles/PMC4405330/

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Transcriptional Profiles of Mart-1(27-35) Epitope Specific TCReng Human CD8+ and CD4+ T Cells upon Epitope Encounter as Elucidated by RNASeq

Autor: Prashant Singh, Bijay Mukherji, Upendra P. Hegde, Sidharth S Jha, David I. Dorsky, Veneta Qendro, Nitya G. Chakraborty, Arvind Chhabra, Richard B. Everson, Umar Farooq, Mei Xiao

Publikováno v: Immunome Research.

Adoptive cell therapy (ACT) with in vitro expanded populations of T cells engineered to express tumor epitope specific T cell receptors (TCR) is now undergoing clinical trials for various malignancies. In this context, ACT with the melanoma epitope,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ed34eedd965f3d70a1b6dbd40d546bcb
https://doi.org/10.4172/1745-7580.s2.004

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Abstract 1305: In vitro analysis of T cells effector vs regulatory function in patients with metastatic melanoma and its correlation to patient outcome

Autor: Upendra P. Hegde, Sidharth S Jha, Nitya G. Chakraborty

Publikováno v: Cancer Research. 75:1305-1305

Back ground: Metastatic melanoma is an aggressive tumor of the epidermal melanocytes with high mortality rates in patients. The anti- melanoma immune response has been extensively studied while immune based treatment strategies are showing promising

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c9b1f50145dfcea65104472695a9dbec
https://doi.org/10.1158/1538-7445.am2015-1305

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