Su1481: IMPACT OF IMMUNOSUPPRESSIVE THERAPIES ON ANTIBODY DECAY FOLLOWING MRNA VACCINATION TO SARS-COV-2 IN A PROSPECTIVE COHORT OF PATIENTS WITH CHRONIC INFLAMMATORY DISEASES

Autor: Deepak, Parakkal, Kim, Wooseob, Paley, Michael, Yang, Monica, Burdess, Samantha, Carvidi, Alexander B., Demissie, Emanuel, El-Qunni, Alia A., Haile, Alem, Huang, Katherine, Escudero, Guadalupe Oliva, McMorrow, Lily E., Paez, Diana, Pawar, Niti, Perantie, Dana C., Schriefer, Rebecca E., Sides, Shannon E., Thapa, Mahima, Gergely, Maté, Akuse, Sewuese E., Klebert, Michael, Mitchell, Lynne, Nix, Billy D., Graf, Jonathan, Taylor, Kimberly E., Chahin, Salim, Ciorba, Matthew A., Katz, Patricia, Matloubian, Mehrdad, O'Halloran, Jane A., Presti, Rachel M., Wu, Gregory F., Gensler, Lianne S., Nakamura, Mary C., Ellebedy, Ali H., Kim, Alfred H.

Publikováno v: In Gastroenterology May 2022 162(7) Supplement:S

Glucocorticoids and B Cell Depleting Agents Substantially Impair Immunogenicity of mRNA Vaccines to SARS-CoV-2.

Autor: Deepak P; Inflammatory Bowel Diseases Center, Division of Gastroenterology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Kim W; Division of Immunobiology, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA., Paley MA; Division of Rheumatology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Yang M; Division of Rheumatology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Carvidi AB; Division of Rheumatology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA., El-Qunni AA; Division of Rheumatology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Haile A; Clinical Trials Unit, Washington University School of Medicine, St. Louis, MO, USA., Huang K; Division of Gastroenterology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Kinnett B; Division of Gastroenterology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Liebeskind MJ; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Liu Z; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA., McMorrow LE; Division of Rheumatology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Paez D; Division of Rheumatology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Perantie DC; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., Schriefer RE; Division of Rheumatology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Sides SE; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., Thapa M; Division of Immunobiology, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA., Gergely M; Division of Gastroenterology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Abushamma S; Division of Gastroenterology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Klebert M; Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Mitchell L; Division of Rheumatology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Nix D; Division of Gastroenterology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Graf J; Division of Rheumatology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Taylor KE; Division of Rheumatology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Chahin S; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., Ciorba MA; Inflammatory Bowels Diseases Center, Division of Gastroenterology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Katz P; Division of Rheumatology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Matloubian M; Division of Rheumatology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA., O'Halloran JA; Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Presti RM; Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Wu GF; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Division of Immunobiology, Department of Pathology and Immunology, Washington, University School of Medicine, St. Louis, MO, USA; The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO, USA., Whelan SPJ; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA., Buchser WJ; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Gensler LS; Division of Rheumatology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA; Arthritis/Immunology Section, San Francisco Veterans Administration Health Care System, San Francisco, CA, USA., Nakamura MC; Division of Rheumatology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA; Arthritis/Immunology Section, San Francisco Veterans Administration Health Care System, San Francisco, CA, USA., Ellebedy AH; Division of Immunobiology, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA; The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO, USA., Kim AHJ; Division of Rheumatology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA; Division of Immunobiology, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA; The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO, USA.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2021 Apr 09. Date of Electronic Publication: 2021 Apr 09.