Výsledky vyhledávání - "Sideridou, M."

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Functional interplay between the DNA-damage-response kinase ATM and ARF tumour suppressor protein in human cancer

Autor: Velimezi, G. Liontos, M. Vougas, K. Roumeliotis, T. Bartkova, J. Sideridou, M. Dereli-Oz, A. Kocylowski, M. Pateras, I.S. Evangelou, K. Kotsinas, A. Orsolic, I. Bursac, S. Cokaric-Brdovcak, M. Zoumpourlis, V. Kletsas, D. Papafotiou, G. Klinakis, A. Volarevic, S. Gu, W. Bartek, J. Halazonetis, T.D. Gorgoulis, V.G.

The DNA damage response (DDR) pathway and ARF function as barriers to cancer development. Although commonly regarded as operating independently of each other, some studies proposed that ARF is positively regulated by the DDR. Contrary to either scena

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::e7af856a81871b4daaa0a33489403517
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3087641

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Cdc6 expression represses E-cadherin transcription and activates adjacent replication origins

Autor: Sideridou, M. Zakopoulou, R. Evangelou, K. Liontos, M. Kotsinas, A. Rampakakis, E. Gagos, S. Kahata, K. Grabusic, K. Gkouskou, K. Trougakos, I.P. Kolettas, E. Georgakilas, A.G. Volarevic, S. Eliopoulos, A.G. Zannis-Hadjopoulos, M. Moustakas, A. Gorgoulis, V.G.

E-cadherin (CDH1) loss occurs frequently in carcinogenesis, contributing to invasion and metastasis. We observed that mouse and human epithelial cell lines overexpressing the replication licensing factor Cdc6 underwent phenotypic changes with mesench

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::9bd066992f6da3eeb309fb093e4a4461
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3089319

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The 3′ UTR IGF2R-A2/B2 variant is associated with increased tumor growth and advanced stages in non-small cell lung cancer

Autor: Kotsinas, A. Evangelou, K. Sideridou, M. Kotzamanis, G. Constantinides, C. Zavras, A.I. Douglass, C.W. Papavassiliou, A.G. Gorgoulis, V.G.

Normal function of Insulin-like Growth Factor II Receptor (IGF2R) gene has been associated with negative control of tumor growth in vivo and in vitro. Rare alleles at a 3′ UTR short tandem repeat polymorphism of IGF2R are known to decrease transcri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::d0faa31f94a41b122b3a158c80c5543c
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3095301

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Oncogene-induced replication stress preferentially targets common fragile sites in preneoplastic lesions. A genome-wide study

Autor: Tsantoulis, P.K. Kotsinas, A. Sfikakis, P.P. Evangelou, K. Sideridou, M. Levy, B. Mo, L. Kittas, C. Wu, X.-R. Papavassiliou, A.G. Gorgoulis, V.G.

Common fragile sites (CFSs) are regions of the genome prone to breakage by replication inhibitors (extrinsic replication stress). Recently, we and others observed that oncogene-induced replication stress (RS) induces DNA damage from the earliest stag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::fd76a86f86dc1230484d5adceced5c5e
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3094553

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Evaluation of claspin as a proliferation marker in human cancer and normal tissues

Autor: Tsimaratou, K. Kletsas, D. Kastrinakis, N. G. Tsantoulis, P. K. Evangelou, K. Sideridou, M. Liontos, M. Poulias, I. and Venere, M. Salmas, M. Kittas, C. Halazonetis, T. D. and Gorgoulis, V. G.

Claspin is a nuclear protein involved in DNA replication and the DNA damage response. Its structural and functional properties suggest that it may represent a potentially useful proliferation marker. To this end, a monoclonal antibody was generated a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::25dfef83737f6d03a264936d5127ec5e
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3116112

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Deregulated overexpression of hCdt1 and hCdc6 promotes malignant behavior

Autor: Liontos, M. Koutsami, M. Sideridou, M. Evangelou, K. Kletsas, D. Levy, B. Kotsinas, A. Nahum, O. Zoumpourlis, V. Kouloukoussa, M. Lygerou, Z. Taraviras, S. Kittas, C. Bartkova, J. Papavassiliou, A.G. Bartek, J. Halazonetis, T.D. Gorgoulis, V.G.

The accurate execution of DNA replication requires a strict control of the replication licensing factors hCdt1 and hCdc6. The role of these key replication molecules in carcinogenesis has not been clarified. To examine how early during cancer develop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::9cafc1144dad6c914dc6dee041361bea
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3094508

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Mutational analysis of the major proline transporter (PrnB) of Aspergillus nidulans

Autor: Tavoularis, SN Tazebay, UH Diallinas, G Sideridou, M and Rosa, A Scazzocchio, C Sophianopoulou, V

PrnB, the L- proline transporter of Aspergillus nidulans, belongs to the Amino acid Polyamine Organocation (APC) transporter family conserved in prokaryotes and eukaryotes. In silico analysis and limited biochemical evidence suggest that APC transpor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::f34a774aab3ff104635828f71a49c088
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3084461

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Akademický článek

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Akademický článek

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