The Effects of Induced Neural Stem Cell Plasticity and Neurogenesis on the Pathology of Alzheimer's Disease

Autor: Siddiqui, Tohid

Alzheimer’s disease (AD) is a progressive and irreversible neurodegenerative disorder that leads to a steady deterioration in mental, behavioral, and social abilities, impairing a person's capacity for independent functioning. It is the most preval

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RNA methyltransferase NSun2 deficiency promotes neurodegeneration through epitranscriptomic regulation of tau phosphorylation.

Autor: Kim, Yoon A., Siddiqui, Tohid, Blaze, Jennifer, Cosacak, Mehmet Ilyas, Winters, Tristan, Kumar, Atul, Tein, Ellen, Sproul, Andrew A., Teich, Andrew F., Bartolini, Francesca, Akbarian, Schahram, Kizil, Caghan, Hargus, Gunnar, Santa-Maria, Ismael

Publikováno v: Acta Neuropathologica; Jan2023, Vol. 145 Issue 1, p29-48, 20p

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Three-Dimensional Biohybrid StarPEG-Heparin Hydrogel Cultures for Modeling Human Neuronal Development and Alzheimer's Disease Pathology.

Autor: Siddiqui T; German Center for Neurodegenerative Diseases (DZNE) Dresden, Helmholtz Association, Dresden, Germany., Celikkaya H; German Center for Neurodegenerative Diseases (DZNE) Dresden, Helmholtz Association, Dresden, Germany., Atasavum ZT; German Center for Neurodegenerative Diseases (DZNE) Dresden, Helmholtz Association, Dresden, Germany.; Leibniz-Institut für Polymerforschung Dresden e.V., Max Bergmann Center of Biomaterials Dresden, Dresden, Germany., Popova S; German Center for Neurodegenerative Diseases (DZNE) Dresden, Helmholtz Association, Dresden, Germany.; Neuron-D GmbH, Dresden, Germany., Freudenberg U; Leibniz-Institut für Polymerforschung Dresden e.V., Max Bergmann Center of Biomaterials Dresden, Dresden, Germany., Werner C; Leibniz-Institut für Polymerforschung Dresden e.V., Max Bergmann Center of Biomaterials Dresden, Dresden, Germany., Kizil C; German Center for Neurodegenerative Diseases (DZNE) Dresden, Helmholtz Association, Dresden, Germany. ck2893@cumc.columbia.edu.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, USA. ck2893@cumc.columbia.edu.; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA. ck2893@cumc.columbia.edu.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2023; Vol. 2561, pp. 159-170.