Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Siddiqua, Hirst"'
Autor:
Xiaowu Liang, Denise L. Doolan, Arlo Randall, Joao C. Aguiar, Suman Sundaresh, Peter L. Blair, Siddiqua Hirst, Daniel Freilich, Berkay Unal, Conrad Valdez, J. Aggrey Oloo, D. Huw Davies, Yunxiang Mu, Douglas M. Molina, Philip L. Felgner, Pierre Baldi
Publikováno v:
PROTEOMICS. 8:4680-4694
A complete description of the serological response following exposure of humans to complex pathogens is lacking and approaches suitable for accomplishing this are limited. Here we report, using malaria as a model, a method which elucidates the profil
Autor:
D. Huw Davies, Bernard Moss, Jenny E. Hernandez, Siddiqua Hirst, Philip L. Felgner, Linda S. Wyatt, Sookhee Chun, Patricia L. Earl, Sharon E. Frey, Frances K. Newman, Douglas M. Molina
Publikováno v:
Journal of Virology. 82:652-663
Modified vaccinia virus Ankara (MVA) is a highly attenuated vaccinia virus that is under consideration as an alternative to the conventional smallpox vaccine Dryvax. MVA was attenuated by extensive passage of vaccinia virus Ankara in chicken embryo f
Autor:
Helen C. Flick-Smith, Joann L. Prior, Richard W. Titball, Pierre Baldi, Siddiqua Hirst, Arlo Randall, D. Huw Davies, Douglas M. Molina, Kate F. Griffin, Philip L. Felgner, Yunxiang Mu, Margaret G. Hartley, Tim Milne, Sarah L. Newstead, Jim E. Eyles, Petra C. F. Oyston, Berkay Unal
Publikováno v:
PROTEOMICS. 7:2172-2183
Stimulation of protective immune responses against intracellular pathogens is difficult to achieve using non-replicating vaccines. BALB/c mice immunized by intramuscular injection with killed Francisella tularensis (live vaccine strain) adjuvanted wi
Autor:
Julien Neel, Douglas M. Molina, Dongling Wang, Sharon J. Peacock, Gladys Tan, Janet S. W. Chew, Ron Yang, Chad Burk, Adam Vigil, Philip L. Felgner, Ganjana Lertmemongkolchai, Richard W. Titball, Narisara Chantratita, D. Huw Davies, Matthew A. Kayala, Pierre Baldi, Rie Nakajima-Sasaki, Greg Bancroft, Melanie Duffield, Jozelyn Pablo, Siddiqua Hirst
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 106(32)
Understanding the way in which the immune system responds to infection is central to the development of vaccines and many diagnostics. To provide insight into this area, we fabricated a protein microarray containing 1,205 Burkholderia pseudomallei pr
Autor:
Jim E, Eyles, Berkay, Unal, Margaret Gill, Hartley, Sarah L, Newstead, Helen, Flick-Smith, Joann L, Prior, Petra C F, Oyston, Arlo, Randall, Yunxiang, Mu, Siddiqua, Hirst, Douglas M, Molina, D Huw, Davies, Tim, Milne, Kate F, Griffin, Pierre, Baldi, Rick W, Titball, Philip L, Felgner
Publikováno v:
Proteomics. 7(13)
Stimulation of protective immune responses against intracellular pathogens is difficult to achieve using non-replicating vaccines. BALB/c mice immunized by intramuscular injection with killed Francisella tularensis (live vaccine strain) adjuvanted wi
Autor:
Inger K. Damon, D. Huw Davies, Siddiqua Hirst, Kevin L. Karem, Xiaowu Liang, Jozelyn Pablo, Luis P. Villarreal, Philip L. Felgner, Rafi Ahmed, Joseph I. Miller, Yunxiang Mu, Douglas M. Molina, Shane Crotty, Jens Wrammert, Rie Nakajima-Sasaki, Berkay Unal
Publikováno v:
Proteomics. 7(10)
The eradication of smallpox by vaccination with vaccinia virus was probably one of the greatest achievements of vaccinology. However, the immunological basis of this protection is not fully understood. To this end, we have used protein microarrays of
Autor:
Pierre Baldi, Siddiqua Hirst, Philip L. Felgner, Denise L. Doolan, Berkay Unal, Yunxiang Mu, Suman Sundaresh, D. Huw Davies
Publikováno v:
Bioinformatics (Oxford, England). 22(14)
Motivation: We present a study of antigen expression signals from a newly developed high-throughput protein microarray technique. These signals are a measure of antibody–antigen binding activity and provide a basis for understanding humoral immune
Autor:
Luis P. Villarreal, Philip L. Felgner, Siddiqua Hirst, Devan Huynh, Yunxiang Mu, Conrad Valdez, D. Huw Davies, Jenny E. Hernandez, Megan McCausland, Shane Crotty
Publikováno v:
Journal of virology. 79(18)
The smallpox vaccine is the prototypic vaccine, yet the viral targets critical for vaccine-mediated protection remain unclear in humans. We have produced protein microarrays of a near-complete vaccinia proteome and used them to determine the major an
Autor:
Xiaowu Liang, D. Huw Davies, Shane Crotty, Mina Kalantari-Dehaghi, Toai T. Nguyen, Pierre Baldi, Philip L. Felgner, Luis P. Villarreal, Arlo Randall, Jenny E. Hernandez, Siddiqua Hirst, Kimberly M. Romero, Yunxiang Mu
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 102(3)
Despite the increasing availability of genome sequences from many human pathogens, the production of complete proteomes remains at a bottleneck. To address this need, a high-throughput PCR recombination cloning and expression platform has been develo
Autor:
D. Huw Davies, Philip L. Felgner, Douglas M. Molina, Brian T. Story, Siddiqua Hirst, Tiana M. Chong, David M. Koelle, Jay Huang, Christopher L. McClurkan, Sookhee Chun, Lichen Jing
Publikováno v:
Journal of Virology. 83:2404-2404
CD4 T cells are required for the maintenance and recall of antiviral CD8 T cells and for antibody responses. Little is known concerning the overall architecture of the CD4 response to complex microbial pathogens. In a whole-proteome approach, 180 pre