Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Siddhesh S Kamat"'
Autor:
Sudipta Mondal, Priyadarshan Kinatukara, Shubham Singh, Sakshi Shambhavi, Gajanan S Patil, Noopur Dubey, Salam Herojeet Singh, Biswajit Pal, P Chandra Shekar, Siddhesh S Kamat, Rajan Sankaranarayanan
Publikováno v:
eLife, Vol 11 (2022)
Chain-length-specific subsets of diacylglycerol (DAG) lipids are proposed to regulate differential physiological responses ranging from signal transduction to modulation of the membrane properties. However, the mechanism or molecular players regulati
Externí odkaz:
https://doaj.org/article/b886c84527514994b0ad7e38a33b0dba
Autor:
Devashish Sen, Babukrishna Maniyadath, Shreyam Chowdhury, Arshdeep Kaur, Subhash Khatri, Arnab Chakraborty, Neelay Mehendale, Snigdha Nadagouda, U.S. Sandra, Siddhesh S. Kamat, Ullas Kolthur-Seetharam
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107128- (2023)
Summary: Coordinated temporal control of gene expression is essential for physiological homeostasis, especially during metabolic transitions. However, the interplay between chromatin architectural proteins and metabolism in regulating transcription i
Externí odkaz:
https://doaj.org/article/0fa2072cb0174e969120f8623865753b
Autor:
Kritee Mehdiratta, Sonam Nain, Meenakshi Sharma, Shubham Singh, Sonali Srivastava, Bhushan Dilip Dhamale, Debasisa Mohanty, Siddhesh S. Kamat, Vivek T. Natarajan, Rakesh Sharma, Rajesh S. Gokhale
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT Type III polyketide synthases (PKSs) found across Streptomyces species are primarily known for synthesis of a vast repertoire of clinically and industrially relevant secondary metabolites. However, our understanding of the functional relevan
Externí odkaz:
https://doaj.org/article/ac9a94a6094b44e89c636a6c75aa12d3
Autor:
Suresh Kumar, Mehak Zahoor Khan, Neha Khandelwal, Chen Chongtham, Biplab Singha, Ankita Dabla, Debashree Behera, Archana Singh, Balasubramanian Gopal, G. Aneeshkumar Arimbasseri, Siddhesh S. Kamat, Vinay Kumar Nandicoori
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Mycobacterium tuberculosis encodes ~200 transcription factors that modulate gene expression under different microenvironments in the host. Even though high-throughput chromatin immunoprecipitation sequencing and transcriptome sequencing (RNA
Externí odkaz:
https://doaj.org/article/463f904daf694b2c99ca67ae6b16d618
Publikováno v:
RSC Chemical Biology. 4:37-46
This review summarizes the recent advances in the development of photoreactive bioorthogonal lipid probes, and the use of these lipid probes in mapping diverse biological pathways in mammalian cells using emerging chemoproteomic approaches.
Autor:
Nora Kory, Susanne Grond, Siddhesh S. Kamat, Zhihuan Li, Natalie Krahmer, Chandramohan Chitraju, Ping Zhou, Florian Fröhlich, Ivana Semova, Christer Ejsing, Rudolf Zechner, Benjamin F. Cravatt, Robert V. Farese, Jr., Tobias C. Walther
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 1, Pp 226-235 (2017)
Variations in the gene LDAH (C2ORF43), which encodes lipid droplet-associated hydrolase (LDAH), are among few loci associated with human prostate cancer. Homologs of LDAH have been identified as proteins of lipid droplets (LDs). LDs are cellular orga
Externí odkaz:
https://doaj.org/article/3ec52a4ce7e4467191376e0d18ab2f9f
Autor:
Kriti Chaplot, Lokesh Pimpale, Balaji Ramalingam, Senthilkumar Deivasigamani, Siddhesh S. Kamat, Girish S. Ratnaparkhi
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 2 (2019)
Familial amyotrophic lateral sclerosis (ALS) is an incurable, late-onset motor neuron disease, linked strongly to various causative genetic loci. ALS8 codes for a missense mutation, P56S, in VAMP-associated protein B (VAPB) that causes the protein to
Externí odkaz:
https://doaj.org/article/3dd5f25ebd454506bed46a64f75f78b8
Autor:
Pooja Kumari, Grace Kaul, T. Anand Kumar, Abdul Akhir, Manjulika Shukla, Suraj Sharma, Siddhesh S. Kamat, Sidharth Chopra, Harinath Chakrapani
Publikováno v:
Microbiology Spectrum. 11
Discovery of novel antibiotics targeting multidrug-resistant (MDR) pathogens such as A. baumannii is an urgent, unmet medical need. Our work has highlighted the potential of this unique scaffold to annihilate MDR A. baumannii alone and in combination
Autor:
Kritee, Mehdiratta, Sonam, Nain, Meenakshi, Sharma, Shubham, Singh, Sonali, Srivastava, Bhushan Dilip, Dhamale, Debasisa, Mohanty, Siddhesh S, Kamat, Vivek T, Natarajan, Rakesh, Sharma, Rajesh S, Gokhale
Publikováno v:
Microbiology spectrum.
Type III polyketide synthases (PKSs) found across
Autor:
Shubham Singh, Siddhesh S. Kamat
Publikováno v:
Eur J Neurosci
Phagocytosis is an important evolutionary conserved process, essential for clearing pathogens and cellular debris in higher organisms, including humans. This well-orchestrated innate immunological response is intricately regulated by numerous cellula