Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Siddhesh Aras"'
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/b1aa4d2f6111438a98b4dd852a68136d
Publikováno v:
Viruses, Vol 15, Iss 12, p 2380 (2023)
Mitochondria have been identified as the “powerhouse” of the cell, generating the cellular energy, ATP, for almost seven decades. Research over time has uncovered a multifaceted role of the mitochondrion in processes such as cellular stress signa
Externí odkaz:
https://doaj.org/article/93497b0594af46a9b3190ddcc2b0ea2a
Autor:
Hussein Chehade, Neeraja Purandare, Alexandra Fox, Nicholas Adzibolosu, Shawn Jayee, Aryan Singh, Roslyn Tedja, Radhika Gogoi, Siddhesh Aras, Lawrence I. Grossman, Gil Mor, Ayesha B. Alvero
Publikováno v:
Translational Oncology, Vol 29, Iss , Pp 101623- (2023)
Cancer progression requires the acquisition of mechanisms that support proliferative potential and metastatic capacity. MNRR1 (also CHCHD2, PARK22, AAG10) is a bi-organellar protein that in the mitochondria can bind to Bcl-xL to enhance its anti-apop
Externí odkaz:
https://doaj.org/article/89a8bc8b63a84bbfb5fbfc3aa920eddc
Autor:
Neeraja Purandare, Yusef Kunji, Yue Xi, Roberto Romero, Nardhy Gomez-Lopez, Andrew Fribley, Lawrence I. Grossman, Siddhesh Aras
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105342- (2022)
Summary: Mitochondria play a key role in placental growth and development, and mitochondrial dysfunction is associated with inflammation in pregnancy pathologies. However, the mechanisms whereby placental mitochondria sense inflammatory signals are u
Externí odkaz:
https://doaj.org/article/4548f7d633da4322b5551fac2a08db3f
Autor:
Kenichiro Motomura, Roberto Romero, Jose Galaz, Li Tao, Valeria Garcia-Flores, Yi Xu, Bogdan Done, Marcia Arenas-Hernandez, Derek Miller, Pedro Gutierrez-Contreras, Marcelo Farias-Jofre, Siddhesh Aras, Lawrence I. Grossman, Adi L. Tarca, Nardhy Gomez-Lopez
Publikováno v:
JCI Insight, Vol 7, Iss 16 (2022)
Preterm birth is the leading cause of neonatal morbidity and mortality worldwide. One of every 4 preterm neonates is born to a mother with intra-amniotic inflammation driven by invading bacteria. However, the molecular mechanisms underlying this host
Externí odkaz:
https://doaj.org/article/1adab97a357348e29510437ecaef7b91
Autor:
Siddhesh Aras, Marie-Claire Maroun, Yeohan Song, Sudeshna Bandyopadhyay, Azadeh Stark, Zeng-Quan Yang, Michael P. Long, Lawrence I. Grossman, Félix Fernández-Madrid
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Autoantibodies function as markers of tumorigenesis and have been proposed to enhance early detection of malignancies. We recently reported, using immunoscreening of a T7 complementary DNA (cDNA) library of breast cancer (BC) prot
Externí odkaz:
https://doaj.org/article/144c3506bb8e455b8220147e9e2300ff
Publikováno v:
Cells, Vol 10, Iss 2, p 197 (2021)
Oxidative phosphorylation is a tightly regulated process in mammals that takes place in and across the inner mitochondrial membrane and consists of the electron transport chain and ATP synthase. Complex IV, or cytochrome c oxidase (COX), is the termi
Externí odkaz:
https://doaj.org/article/62ddc324c02b4dc3bebef297c16ed2d5
Publikováno v:
PLoS Pathogens, Vol 5, Iss 6, p e1000469 (2009)
Epstein-Barr Nuclear Antigen 1 (EBNA1) is essential for Epstein-Barr virus to immortalize naïve B-cells. Upon binding a cluster of 20 cognate binding-sites termed the family of repeats, EBNA1 transactivates promoters for EBV genes that are required
Externí odkaz:
https://doaj.org/article/92dc5a53f0f240faa6d040d0b9fff230
Autor:
Mariachiara Bosco, Roberto Romero, Dahiana M. Gallo, Manaphat Suksai, Francesca Gotsch, Eunjung Jung, Piya Chaemsaithong, Adi L. Tarca, Nardhy Gomez-Lopez, Marcia Arenas-Hernandez, Arun Meyyazhagan, Malek Al Qasem, Massimo P. Franchi, Lawrence I. Grossman, Siddhesh Aras, Tinnakorn Chaiworapongsa
Publikováno v:
The Journal of Maternal-Fetal & Neonatal Medicine. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21577f08690d56dd51877b1b8e5db843
https://doi.org/10.1080/14767058.2023.2183088
https://doi.org/10.1080/14767058.2023.2183088
Autor:
Sonam Popli, Sukanya Chakravarty, Shumin Fan, Anna Glanz, Siddhesh Aras, Laura E. Nagy, Ganes C. Sen, Ritu Chakravarti, Saurabh Chattopadhyay
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(37)
Interferon (IFN) regulatory factor 3 (IRF3) is a transcription factor activated by phosphorylation in the cytoplasm of a virus-infected cell; by translocating to the nucleus, it induces transcription of IFN-β and other antiviral genes. We have previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b34c996a5eef9c490ce3eb6e5c85443
https://pubmed.ncbi.nlm.nih.gov/36067309
https://pubmed.ncbi.nlm.nih.gov/36067309