Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Siddhartha Mondragón-Rodríguez"'
Autor:
Siddhartha Mondragón-Rodríguez, Benito Ordaz, Erika Orta-Salazar, Sofia Díaz-Cintra, Fernando Peña-Ortega, George Perry
Publikováno v:
Bio-Protocol, Vol 10, Iss 4 (2020)
Transgenic mice have been used to make valuable contributions to the field of neuroscience and model neurological diseases. The simultaneous functional analysis of hippocampal cell activity combined with hippocampal dependent innate task evaluations
Externí odkaz:
https://doaj.org/article/3d6a9080d4254ed9b07434a27f837373
Publikováno v:
Neural Plasticity, Vol 2020 (2020)
For more than five decades, the field of Alzheimer’s disease (AD) has focused on two main hypotheses positing amyloid-beta (Aβ) and Tau phosphorylation (pTau) as key pathogenic mediators. In line with these canonical hypotheses, several groups aro
Externí odkaz:
https://doaj.org/article/c13d3de12b2f4d0eba99a421552b9ca3
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Alzheimer’s disease (AD) is defined by the presence of amyloid-β (Aβ) and tau protein aggregates. However, increasing data is suggesting that brain network alterations rather than protein deposition could account for the early pathogenesis of the
Externí odkaz:
https://doaj.org/article/bed75123f5b44534817fa6f1f86d485f
Autor:
Siddhartha Mondragón-Rodríguez, George Perry, Xiongwei Zhu, Paula I. Moreira, Sylvain Williams
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2012 (2012)
Glycogen synthase kinase 3 (GSK3) has been implicated in neurological disorders; therefore, it is not surprising that there has been an increased focus towards developing therapies directed to this kinase. Unfortunately, these current therapies have
Externí odkaz:
https://doaj.org/article/f11671560fea4227923b69d824cac5c2
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2012 (2012)
Alzheimer’s disease (AD) is defined by the concurrence of accumulation of abnormal aggregates composed of two proteins: Amyloid beta (Aβ) and tau, and of cellular changes including neurite degeneration and loss of neurons and cognitive functions.
Externí odkaz:
https://doaj.org/article/638414c97a7e4465aeba84a4da2054f2
Autor:
Lorena Xolalpa-Cueva, Carlos Antonio García-Carlos, Rocío Villaseñor-Zepeda, Erika Orta-Salazar, Sofia Díaz-Cintra, Fernando Peña-Ortega, George Perry, Siddhartha Mondragón-Rodríguez
Publikováno v:
Journal of Alzheimer's Disease. 87:529-543
Background: Tau hyperphosphorylation at several sites, including those close to its microtubule domain (MD), is considered a key pathogenic event in the development of tauopathies. Nevertheless, we recently demonstrated that at the very early disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf4235b7d842bb0c1cfebc55f8bfe847
https://doi.org/10.3233/jad-215186
https://doi.org/10.3233/jad-215186
Autor:
Siddhartha Mondragón‐Rodríguez, Lorena Cueva‐Xolalpa, Carlos García‐Carlos, Rocío Villaseñor‐Zepeda, Erika Orta‐Salazar, Sofia Díaz‐Cintra, Fernando Peña‐Ortega, George Perry
Publikováno v:
Alzheimer's & Dementia. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::baccbafdd494fe04e246a6e152553031
https://doi.org/10.1002/alz.058539
https://doi.org/10.1002/alz.058539
Publikováno v:
Neural Plasticity
Neural Plasticity, Vol 2020 (2020)
Neural Plasticity, Vol 2020 (2020)
For more than five decades, the field of Alzheimer’s disease (AD) has focused on two main hypotheses positing amyloid-beta (Aβ) and Tau phosphorylation (pTau) as key pathogenic mediators. In line with these canonical hypotheses, several groups aro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22800d62e6e7c28b9b2c57dcbba290fd
https://pubmed.ncbi.nlm.nih.gov/32952546
https://pubmed.ncbi.nlm.nih.gov/32952546
Autor:
George Perry, Siddhartha Mondragón-Rodríguez, Fernando Peña-Ortega, Benito Ordaz, Sofía Díaz-Cintra, Erika Orta-Salazar
Publikováno v:
Bio Protoc
Transgenic mice have been used to make valuable contributions to the field of neuroscience and model neurological diseases. The simultaneous functional analysis of hippocampal cell activity combined with hippocampal dependent innate task evaluations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61d8260e550f857f0801b59063b4a8b0
https://doi.org/10.21769/bioprotoc.3529
https://doi.org/10.21769/bioprotoc.3529
Autor:
Siddhartha Mondragón-Rodríguez, Sofía Díaz-Cintra, Martín Macías, Sylvain Williams, Fernando Peña-Ortega, Azucena Aguilar-Vázquez, Benito Ordaz, George Perry, Erika Orta-Salazar, Perla González-Pereyra, Anahí Salas-Gallardo
Publikováno v:
Journal of Biological Chemistry. 293:8462-8472
Tau hyperphosphorylation at several sites, including those close to the microtubule domain region (MDr), is considered a key pathological event in the development of Alzheimer's disease (AD). Recent studies indicate that at the very early stage of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::540637cd9c56ca4cc4a309c19808d4d5
https://doi.org/10.1074/jbc.ra117.001187
https://doi.org/10.1074/jbc.ra117.001187