Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Siddhartha Ak Datta"'
Autor:
Mauricio Comas-Garcia, Tomas Kroupa, Siddhartha AK Datta, Demetria P Harvin, Wei-Shau Hu, Alan Rein
Publikováno v:
eLife, Vol 7 (2018)
The principal structural component of a retrovirus particle is the Gag protein. Retroviral genomic RNAs contain a ‘packaging signal’ (‘Ψ') and are packaged in virus particles with very high selectivity. However, if no genomic RNA is present, G
Externí odkaz:
https://doaj.org/article/7fbaa5c7b160404090290a40ca2bb2f6
Autor:
Mauricio Comas-Garcia, Siddhartha AK Datta, Laura Baker, Rajat Varma, Prabhakar R Gudla, Alan Rein
Publikováno v:
eLife, Vol 6 (2017)
Selective packaging of HIV-1 genomic RNA (gRNA) requires the presence of a cis-acting RNA element called the ‘packaging signal’ (Ψ). However, the mechanism by which Ψ promotes selective packaging of the gRNA is not well understood. We used fluo
Externí odkaz:
https://doaj.org/article/09617f0b4cb14182a2d740afa6b31500
Autor:
Joseph M Watts, Cristina Gherge, Christopher W. Leonard, Alan Rein, Justin T. Low, Tania Lombo, Robert J. Gorelick, Stefanie A Knoepfel, Julian W. Bess, Siddhartha Ak Datta, Ben Berkhout, Kevin M. Weeks, Olivier ter Brake
Publikováno v:
Retrovirology, Vol 8, Iss Suppl 2, p O1 (2011)
Retrovirology
Retrovirology
Our laboratory is blending new RNA chemistries, largely directed at the ribose 2'-hydroxyl group, with quantitative interpretation to create new kinds of chemical microscopes for accurate RNA structure analysis. This seminar will focus on two example