Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Siddharth Shenoy"'
Publikováno v:
Bio-Protocol, Vol 9, Iss 13 (2019)
In health, the high-speed airflow associated with cough represents a vital backup mechanism for clearing accumulated mucus from our airways. However, alterations in the mucus layer in cystic fibrosis (CF) and chronic obstructive pulmonary disease (CO
Externí odkaz:
https://doaj.org/article/6ab394a292d84bfe9307d50461d55532
Autor:
Siddharth Shenoy, Prabhanshu Shekhar, Frank Heinrich, Marie-Claire Daou, Arne Gericke, Alonzo H Ross, Mathias Lösche
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e32591 (2012)
The structure and function of the PTEN phosphatase is investigated by studying its membrane affinity and localization on in-plane fluid, thermally disordered synthetic membrane models. The membrane association of the protein depends strongly on membr
Externí odkaz:
https://doaj.org/article/a0234e90a9624ce5a389cec00bf46f4c
Publikováno v:
2022 2nd Asian Conference on Innovation in Technology (ASIANCON).
Autor:
Akhil Khubchandani, Aratrika Ray, Siddharth Shenoy, Canute Rolin Cardoza, Chandrashekhar Pomu Chavan
Publikováno v:
2022 IEEE 7th International conference for Convergence in Technology (I2CT).
Publikováno v:
Journal of Structural Biology. 180:394-408
The phosphatidylinositolphosphate phosphatase PTEN is the second most frequently mutated protein in human tumors. Its membrane association, allosteric activation and membrane dissociation are poorly understood. We recently reported PTEN binding affin
Autor:
Siddharth Shenoy, Zhao Qin, Markus J. Buehler, Agnieszka Kalinowski, Peter N. Yaron, Mathias Lösche, Kris Noel Dahl
Publikováno v:
PMC
Hutchinson–Gilford progeria syndrome is a premature aging disorder associated with the expression of ∆50 lamin A (∆50LA), a mutant form of the nuclear structural protein lamin A (LA). ∆50LA is missing 50 amino acids from the tail domain and r
Autor:
Frank Heinrich, Mathias Lösche, Gediminas Niaura, Rima Budvytyte, Mindaugas Mickevicius, Gintaras Valincius, David J. Vanderah, Prabhanshu Shekhar, Haw-Zan Goh, Siddharth Shenoy, Hilary Chapman, Vladislava Voiciuk
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 29(27)
The self-assembled monolayers (SAMs) of new lipidic anchor molecule HC18 [Z-20-(Z-octadec-9-enyloxy)-3,6,9,12,15,18,22-heptaoxatetracont-31-ene-1-thiol] and mixed HC18/β-mercaptoethanol (βME) SAMs were studied by spectroscopic ellipsometry, contact
Publikováno v:
Biophysical Journal. 104(2)
The phosphatidylinositolphosphate phosphatase PTEN is the second most frequently mutated protein in human tumors. Its membrane association, allosteric activation and membrane dissociation are poorly understood. We recently reported PTEN binding affin
Autor:
Mathias Lösche, Siddharth Shenoy, Arne Gericke, Alonzo H. Ross, Marie-Claire Daou, Frank Heinrich, Prabhanshu Shekhar
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 4, p e32591 (2012)
PLoS ONE, Vol 7, Iss 4, p e32591 (2012)
The structure and function of the PTEN phosphatase is investigated by studying its membrane affinity and localization on in-plane fluid, thermally disordered synthetic membrane models. The membrane association of the protein depends strongly on membr
Publikováno v:
Biophysical Journal. 98(3)
The complexity of cells makes molecular-scale characterizations of structure and interactions of biomembranes in vivo extremely difficult, thus driving the development of synthetic membrane models. tBLMs are resilient biomimetic systems stabilized by