Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Siddharth, Nanguneri"'
Autor:
Sarit S. Agasti, Sivan Ironi, Siddharth Nanguneri, Kobi Rosenblum, Noga Gershoni-Emek, Ranjan Sasmal, Mohammad Hleihil, Deepak T. Nair, Iliana Barrera, Bella Koltun
Publikováno v:
Nucleic Acids Research
In neurons, the specific spatial and temporal localization of protein synthesis is of great importance for function and survival. Here, we visualized tRNA and protein synthesis events in fixed and live mouse primary cortical culture using fluorescent
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e38098 (2012)
Three-dimensional fluorescence imaging of thick tissue samples with near-molecular resolution remains a fundamental challenge in the life sciences. To tackle this, we developed tomoSTORM, an approach combining single-molecule localization-based super
Externí odkaz:
https://doaj.org/article/603440a5ae024e859bd357a7c58692ec
Autor:
Deepak T. Nair, Reddy Peera Kommaddi, Deepti Bapat, David A. Bennett, Siddharth Nanguneri, Vijayalakshmi Ravindranath, Smitha Karunakaran, Debajyoti Das, Ajit Ray, Eisha Shaw
Publikováno v:
The Journal of Neuroscience
Dendritic spine loss is recognized as an early feature of Alzheimer's disease (AD), but the underlying mechanisms are poorly understood. Dendritic spine structure is defined by filamentous actin (F-actin) and we observed depolymerization of synaptoso
Autor:
Siddharth, Nanguneri, R T, Pramod, Nadia, Efimova, Debajyoti, Das, Mini, Jose, Tatyana, Svitkina, Deepak, Nair
Publikováno v:
eNeuro
Visual Abstract
The cytoarchitecture of a neuron is very important in defining morphology and ultrastructure. Although there is a wealth of information on the molecular components that make and regulate these ultrastructures, there is a dearth o
The cytoarchitecture of a neuron is very important in defining morphology and ultrastructure. Although there is a wealth of information on the molecular components that make and regulate these ultrastructures, there is a dearth o
Autor:
Patrick Aebischer, Deepak T. Nair, Debajyoti Das, Bernard L. Schneider, Ajit Ray, Reddy Peera Kommaddi, Siddharth Nanguneri, Vijayalakshmi Ravindranath
Publikováno v:
Alzheimer's & Dementia. 13
Autor:
Siddharth Nanguneri, Nadia Efimova, Deepak T. Nair, Mini Jose, Debajyoti Das, Tatyana Svitkina, R. T. Pramod
Publikováno v:
eneuro. 6:ENEURO.0425-18.2019
The cytoarchitecture of a neuron is very important in defining morphology and ultrastructure. Although there is a wealth of information on the molecular components that make and regulate these ultrastructures, there is a dearth of understanding of ho
Autor:
Siddharth, Nanguneri, Benjamin, Flottmann, Frank, Herrmannsdörfer, Kuner, Thomas, Mike, Heilemann
Publikováno v:
Microscopy research and technique. 77(7)
Photophysical properties of any fluorophore are governed by the chemical nanoenvironment. In the context of imaging biological samples, this translates to different photophysical properties for different labels and probes. Here, we demonstrate that t
Autor:
Siddharth Nanguneri, Latha Diwakar, Deepak T. Nair, Ajit Ray, Vijayalakshmi Ravindranath, Reddy Peera Kommaddi, Debajyoti Das
Publikováno v:
Free Radical Biology and Medicine. 100:S160
Oxidative stress is known to be one of the major contributors towards the pathogenesis of Alzheimer’s disease (AD) potentially leading to amyloid plaques, neurofibrillary tangles and loss of dendritic spine morphology. As a marker for ongoing oxida
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e38098 (2012)
PLoS ONE
PLoS ONE
Three-dimensional fluorescence imaging of thick tissue samples with near-molecular resolution remains a fundamental challenge in the life sciences. To tackle this, we developed tomoSTORM, an approach combining single-molecule localization-based super
Autor:
Smitha Karunakaran, Vijayalakshmi Ravindranath, Deepika Singh Tomar, Siddharth Nanguneri, Ajit Ray, Deepak T. Nair, Deepti Bapat, Bernard L. Schneider, Reddy Peera Kommaddi
Aims: Reactive oxygen species (ROS) generated during Alzheimer's disease (AD) pathogenesis through multiple sources are implicated in synaptic pathology observed in the disease. We have previously shown F-actin disassembly in dendritic spines in earl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f676ecfe98a38204dcfab8f1c94f851
https://infoscience.epfl.ch/record/272758
https://infoscience.epfl.ch/record/272758