Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Siddartha Datta Gupta"'
Autor:
Gayatri Sharma, Sameer Mirza, Yi-Hsin Yang, Rajinder Parshad, Priya Hazrah, Siddartha Datta Gupta, Ranju Ralhan
Publikováno v:
Cellular Oncology, Vol 31, Iss 6, Pp 487-500 (2009)
Background: Methylation-mediated suppression of detoxification, DNA repair and tumor suppressor genes has been implicated in cancer development. This study was designed to investigate the impact of concurrent methylation of multiple genes in breast t
Externí odkaz:
https://doaj.org/article/3c8159e2131e405c9d058df1c1489420
Publikováno v:
Tumor Biology. 33:1837-1843
Identification of biomarkers for monitoring efficacy of neoadjuvant chemotherapy in breast cancer patients is of utmost importance in individual tailoring of treatment and save from toxicity due to non-effective drugs. We hypothesized that methylatio
Autor:
Gayatri Sharma, Rajinder Parshad, Ranju Ralhan, Sameer Mirza, Pranav Pandya, Anurag Srivastava, Siddartha Datta Gupta
Publikováno v:
Life Sciences. 87:83-91
Aims The clinical relevance of frequent methylation of CpG islands of key cancer genes in breast cancer is being increasingly recognized. Our study aimed to evaluate the promoter methylation status of DNA repair genes—BRCA1MGMT and GSTP1 i
Autor:
Gayatri Sharma, Siddartha Datta Gupta, Rajinder Parshad, Sameer Mirza, Anurag Srivastava, Ranju Ralhan
Publikováno v:
Clinical Biochemistry. 43:380-386
Objectives: The objective of this study was to determine the concordance of promoter methylation of stratifin , ERα and PR in tumor and circulating DNA in breast cancer patients and their association with clinicopathological parameters and disease p
Autor:
Gayatri Sharma, Ranju Ralhan, Rajinder Parshad, Anurag Srivastava, Sameer Mirza, Siddartha Datta Gupta, Pranav Pandya
Publikováno v:
Clinical Biochemistry. 43:373-379
Objectives: Multidrug resistance 1 (MDR1) gene encodes P-glycoprotein (P-gp), a transmembrane calcium-dependent efflux pump, implicated in drug resistance. In this prospective study, methylation status of MDR1 promoter and its correlation with clinic
Autor:
Sudhir Bahadur, Shaun Ghanny, Ranju Ralhan, Satyendra C. Tripathi, K. W. Michael Siu, Ajay Matta, Siddartha Datta Gupta, Leroi V. DeSouza
Publikováno v:
Molecular & Cellular Proteomics. 7:1162-1173
Multidimensional LC-MS/MS has been used for the analysis of biological samples labeled with isobaric mass tags for relative and absolute quantitation (iTRAQ) to identify proteins that are differentially expressed in human head-and-neck squamous cell
Autor:
Sameer Mirza, Siddartha Datta Gupta, Gayatri Sharma, Ranju Ralhan, Anurag Srivastava, Rajinder Parshad
Publikováno v:
Annals of surgical oncology. 19(9)
To determine concordance of promoter hypermethylation of ERβ (estrogen receptor β) and RARβ2 (retinoic acid receptor β2) in tumor and circulating DNA of Indian breast cancer patients and their association with clinicopathologic parameters and dis
Autor:
Anoop Saraya, Ranju Ralhan, Siddartha Datta Gupta, Tushar K. Chattopadhyay, Rinu Sharma, Tasneem Kausar, Md. Raghibul Hasan
Publikováno v:
Cellular oncology (Dordrecht). 34(3)
Expression of oncostatin M receptor beta (OSMRβ) has been reported in human cancers, however its role in esophageal squamous cell carcinoma (ESCC) remains unknown. Using differential display, earlier we reported the identification of an alternativel
Autor:
Ranju Ralhan, Rinu Sharma, Md. Raghibul Hasan, Satyendra C. Tripathi, Tushar K. Chattopadhyay, Siddartha Datta Gupta, Anoop Saraya, Tasneem Kausar
Publikováno v:
Cancer investigation. 29(1)
Proteins do not operate as individual units, and components of intracellular canonical pathways often cross talk in tumor genesis. We hypothesized that G-protein-coupled receptor 56 (GPR56), transglutaminase (TG2), and nuclear factor-κB (NF-κB) may
Autor:
Pranav Pandya, Anurag Srivastava, Rajinder Parshad, Ranju Ralhan, Sameer Mirza, Siddartha Datta Gupta, Gayatri Sharma
Publikováno v:
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 32(1)
Maspin is a serine protease inhibitor with tumor-suppressor activity. Maspin can suppress tumor growth and metastasis in vivo and tumor cell motility and invasion in vitro. Previous studies indicate that the loss of Maspin expression is closely linke