Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Siddarth Venkatesh"'
Autor:
Siddarth Venkatesh, Paul D Bieniasz
Publikováno v:
PLoS Pathogens, Vol 9, Iss 7, p e1003483 (2013)
Tetherin, an interferon-inducible membrane protein, inhibits the release of nascent enveloped viral particles from the surface of infected cells. However, the mechanisms underlying virion retention have not yet been fully delineated. Here, we employ
Externí odkaz:
https://doaj.org/article/738abc8746c04cbea2f0fec20e577b88
Autor:
Michael J. Barratt, Sharika Nuzhat, Kazi Ahsan, Steven A. Frese, Aleksandr A. Arzamasov, Shafiqul Alam Sarker, M. Munirul Islam, Parag Palit, Md Ridwan Islam, Matthew C. Hibberd, Swetha Nakshatri, Carrie A. Cowardin, Janaki L. Guruge, Alexandra E. Byrne, Siddarth Venkatesh, Vinaik Sundaresan, Bethany Henrick, Rebbeca M. Duar, Ryan D. Mitchell, Giorgio Casaburi, Johann Prambs, Robin Flannery, Mustafa Mahfuz, Dmitry A. Rodionov, Andrei L. Osterman, David Kyle, Tahmeed Ahmed, Jeffrey I. Gordon
Publikováno v:
Sci Transl Med
Disrupted development of the gut microbiota is a contributing cause of childhood malnutrition. Bifidobacterium longum subspecies infantis is a prominent early colonizer of the infant gut that consumes human milk oligosaccharides (HMOs). We found that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcac5508b2ec685aba218c541d0ff3d2
https://europepmc.org/articles/PMC9516695/
https://europepmc.org/articles/PMC9516695/
Autor:
James S. Weagley, Mark Zaydman, Siddarth Venkatesh, Yo Sasaki, Neha Damaraju, Alex Yenkin, William Buchser, Dmitry A. Rodionov, Andrei Osterman, Tahmeed Ahmed, Michael J. Barratt, Aaron DiAntonio, Jeffrey Milbrandt, Jeffrey I. Gordon
Publikováno v:
Cell Reports. 39:110738
Perturbed gut microbiome development has been linked to childhood malnutrition. Here, we characterize bacterial Toll/interleukin-1 receptor (TIR) protein domains that metabolize nicotinamide adenine dinucleotide (NAD), a co-enzyme with far-reaching e
Autor:
Ishita Mostafa, Hao Wei Chang, Robert L. Hettich, Matthew C. Hibberd, Robert Y. Chen, Sathish Subramanian, Nuzhat Choudhury, M Munirul Islam, Vanderlene L. Kung, Clay F. Semenkovich, Aleksandr A. Arzamasov, Siddarth Venkatesh, Sayeeda Huq, Richard J. Giannone, Martin Meier, Mustafa Mahfuz, Andrei L. Osterman, Christopher S. Sawyer, Bernard Henrissat, Imteaz Mahmud, Larry D. Spears, Iqbal Hossain, Christopher B. Newgard, Shafiqul Alam Sarker, Michael J. Muehlbauer, Richard D. Head, Dmitry A. Rodionov, Michael Talcott, Jeffrey I. Gordon, Olga Ilkayeva, Tahmeed Ahmed, Jiye Cheng, Semen A. Leyn, Michael J. Barratt, David O'Donnell, Jeanette L. Gehrig, Carrie A. Cowardin
Publikováno v:
Science (New York, N.y.)
Science
Science, 2019, 365 (6449), ⟨10.1126/science.aau4732⟩
Science, American Association for the Advancement of Science, 2019, 365 (6449), ⟨10.1126/science.aau4732⟩
Science
Science, 2019, 365 (6449), ⟨10.1126/science.aau4732⟩
Science, American Association for the Advancement of Science, 2019, 365 (6449), ⟨10.1126/science.aau4732⟩
To examine the contributions of impaired gut microbial community development to childhood undernutrition, we combined metabolomic and proteomic analyses of plasma samples with metagenomic analyses of fecal samples to characterize the biological state
Autor:
Gagandeep Kang, Michael J. Barratt, M Munirul Islam, Tahmeed Ahmed, Rashidul Haque, Siddarth Venkatesh, Matthew C. Hibberd, William A. Petri, Hao Wei Chang, Ishita Mostafa, Jeanette L. Gehrig, Arjun S. Raman, Margaret Kosek, Sayeeda Huq, Aldo A. M. Lima, Pascal O. Bessong, Dmitry A. Rodionov, Aleksandr A. Arzamasov, Andrei L. Osterman, Mustafa Mahfuz, Jeffrey I. Gordon, Semen A. Leyn, Sathish Subramanian
Publikováno v:
Science. 365:eaau4735
Characterizing the organization of the human gut microbiota is a formidable challenge given the number of possible interactions between its components. Using a statistical approach initially applied to financial markets, we measured temporally conser
Autor:
Indi Trehan, Per Ashorn, Kenneth Maleta, Tarek Salih, Christopher B. Newgard, Semen A. Leyn, Jeffrey I. Gordon, Sathish Subramanian, Bernard Henrissat, Yue-Mei Fan, Andrei L. Osterman, Josh M Jorgensen, Kathryn G. Dewey, Michael J. Barratt, Olga Ilkaveya, Mark R. Charbonneau, Laura V. Blanton, Siddarth Venkatesh, Mark J. Manary, Dmitry A. Rodionov
Publikováno v:
Science (New York, N.Y.), vol 351, iss 6275
Microbiota and infant development Malnutrition in children is a persistent challenge that is not always remedied by improvements in nutrition. This is because a characteristic community of gut microbes seems to mediate some of the pathology. Human gu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f693f1aa919a6a63294a4dceb024e75c
https://europepmc.org/articles/PMC4787260/
https://europepmc.org/articles/PMC4787260/
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 69:852-860
Molecular imprinting provides a rational design strategy for the development of controlled release drug delivery systems. We demonstrate that imprinting a hydrogel network results in macromolecular memory for the template molecule, indicated by the t
Publikováno v:
Journal of Controlled Release. 124:154-162
Zero-order or concentration independent release kinetics are highly desirable from drug delivery devices. In this paper we demonstrate experimentally, for the first time, zero-order release of a small molecular weight therapeutic, ketotifen fumarate
The human gut contains a microbial community composed of tens of trillions of organisms that normally assemble during the first 2–3 y of postnatal life. We propose that brain development needs to be viewed in the context of the developmental biolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b5d0925b5cd897442fb6c0f0a2d35a
https://europepmc.org/articles/PMC4655552/
https://europepmc.org/articles/PMC4655552/
Publikováno v:
Expert Opinion on Drug Delivery. 2:1085-1096
This review article highlights recent activities in the field of biomimetic systems and their application in controlled drug delivery. A definition and overview of biomimetic processes is given, with a focus on synthesis and assembly for the creation