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Autor:
Mehmet Altay Unal, Ceylan Verda Bitirim, Julia Somers, Gokce Yagmur Summak, Omur Besbinar, Ebru Kocakaya, Cansu Gurcan, Hasan Nazir, Zeynep Busra Aksoy Ozer, Sibel Aysil Ozkan, Sidar Bereketoglu, Aykut Ozkul, Emek Demir, Kamil Can Akcali, Acelya Yilmazer
Heme oxygenase-1 (HO-1) is a stress-induced enzyme that catalyzes the breakdown of heme into biliverdin, carbon monoxide, and iron. Targeting HO-1 to treat severe COVID-19 has been suggested by several groups, yet the role of HO-1 in SARS-CoV-2 infec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a5dcef7373beafea6fa999a4ee7d41d
https://doi.org/10.1101/2022.05.24.493187
https://doi.org/10.1101/2022.05.24.493187
Publikováno v:
Turkish Journal of Pharmaceutical Sciences
Turkish Journal of Pharmaceutical Sciences, Vol 16, Iss 2, Pp 206-210 (2019)
Turkish Journal of Pharmaceutical Sciences, Vol 16, Iss 2, Pp 206-210 (2019)
Objectives Isolation of enzymes and experiments on them require great effort and cost and are time-consuming. Therefore, it is important to extend the usability of the enzymes by immobilizing them. In this study our purpose was to immobilize the enzy
Autor:
Alpay Azap, Sibel A. Ozkan, Gokce Yagmur Summak, Dunya Aydos, Hasan Nazir, Nil Demir, Merve Murat, Inci Cevher Zeytin, Emek Demir, Julia Somers, Ezgi Goksoy, Açelya Yilmazer, Ceylan Verda Bitirim, Kamil Can Akcali, Zeynep Busra Aksoy Ozer, Aykut Ozkul, Sidar Bereketoglu, Zeynep Eran, Omur Besbinar, Cansu Gurcan, Ebru Kocakaya, Mehmet Ünal
Publikováno v:
Canadian journal of physiology and pharmacology. 99(5)
Ribavirin is a guanosine analog with broad-spectrum antiviral activity against RNA viruses. Based on this, we aimed to show the anti-SARS-CoV-2 activity of this drug molecule via in vitro, in silico, and molecular techniques. Ribavirin showed antivir
Autor:
Nil Demir, Julia Somers, Sibel A. Ozkan, Ceylan Verda Bitirim, Zeynep Eran, Sidar Bereketoglu, Alpay Azap, Ebru Kocakaya, Mehmet Ünal, Ezgi Goksoy, Emek Demir, Cansu Gurcan, Açelya Yilmazer, Omur Bul, Merve Murat, Kamil Can Akcali, Inci Cevher Zeytin, Aykut Ozkul, Dunya Aydos, Gokce Yagmur Summak, Hasan Nazir
Ribavirin is a guanosine analog with broad-spectrum antiviral activity against RNA viruses. Based on this, we aimed to show the anti-SARS-CoV-2 activity of this drug molecule via in vitro, in silico, and molecular techniques. Ribavirin showed antivir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbef10eb8b61d4de27bc924e5ab6d693
https://doi.org/10.1101/2020.12.04.410092
https://doi.org/10.1101/2020.12.04.410092