Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Sickle cell gene"'
Publikováno v:
Journal of Applied Hematology, Vol 14, Iss 2, Pp 78-86 (2023)
BACKGROUND: Homocysteinemia is regarded as potential predictor for vaso-occlusive phenomenon often observed in sickle cell hemoglobinopathy. The objective was to determine the relationship of these genotypes with homocysteinemia and the predictive co
Externí odkaz:
https://doaj.org/article/ce0c4948c3e74cd994334561bedae9bf
Autor:
Philip Olusola
Publikováno v:
Annals of Health Research, Vol 4, Iss 2, Pp 88-96 (2018)
Evolutionally, the single nucleotide mutation responsible for the sickle haemoglobin gene, (HbS gene) developed from the regions of the world where malaria is holoendemic, leading to the explanation that the mutation is in response to the presence of
Externí odkaz:
https://doaj.org/article/b8efd2e8530a41b482519b611036d203
Autor:
Cormac Sheridan
Publikováno v:
Nature Biotechnology. 39:1320-1323
Early results promise a one-off treatment, but gene-editing and gene therapies will have to show durable protection and be affordable to the many patients with sickle cell disease in the world.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c842420c3b6988aeb2707206001ecf2
https://doi.org/10.1038/s41587-021-01121-0
https://doi.org/10.1038/s41587-021-01121-0
Akademický článek
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Autor:
Amir Assumani N’Simbo, Matthieu Ngombe, Sanislas Wembonyama, Oscar Luboya Numbi, Dieudonné Ngwej Tshikwej, Gautier Mutoba, Léon Tshilolo, Tina Katamea, Dieudonné Bafwafwa, Criss Koba Mjumbe, Maguy Ngongo Omoy, Lydie Kasongo
Publikováno v:
OALib. :1-12
Sickle cell anemia is a blood disorder linked to an abnormality in the structure of hemoglobin. The objective of this study was to determine the frequency of the sickle cell gene on the basis of early detection of hemoglobin using the isoelectric foc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3469745a921facc7d0f21d9a5bc92234
https://doi.org/10.4236/oalib.1106121
https://doi.org/10.4236/oalib.1106121
Autor:
German F Sáenz-Renauld
Publikováno v:
Acta Médica Costarricense, Vol 47, Iss 4, Pp 173-179 (2005)
Es notorio que en Costa Rica la frecuencia de las variantes más comunes de la hemoglobina (Hb) (S Y C) puede ser trazada desde África. Estas hemoglobinas son dos marcadores genéticos que han mantenido un equilibrado polimorfismo contra la presión
Externí odkaz:
https://doaj.org/article/6c61ed2e6005412c8a5b78934be5a685
Publikováno v:
The Pan African Medical Journal, Vol 18, Iss 13 (2014)
Sickle cell disease (SCD) is one of the most common inherited disorders of haemoglobin in Africa and it is expected that sickle cell trait varies in frequency in different areas in Sudan. An extensive literature search was carried out accessing the U
Externí odkaz:
https://doaj.org/article/4495c31fec09497dbfd832b4a7d2ab5a
Autor:
Phillip O Olatunji
Publikováno v:
Annals of Health Research, Vol 4, Iss 2, Pp 88-96 (2018)
Evolutionally, the single nucleotide mutation responsible for the sickle haemoglobin gene, (HbS gene) developed from the regions of the world where malaria is holoendemic, leading to the explanation that the mutation is in response to the presence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78c9411a7052711337a027ee00b138f1
https://doi.org/10.30442/ahr.0402-1-12
https://doi.org/10.30442/ahr.0402-1-12
Autor:
Ayoola Odeyemi
Publikováno v:
Nephrology Dialysis Transplantation. 34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67cef09b71dd43d90f9d75909a3e3b7e
https://doi.org/10.1093/ndt/gfz103.sp006
https://doi.org/10.1093/ndt/gfz103.sp006
Autor:
Anietie Ekong
Publikováno v:
InnovAiT: Education and inspiration for general practice. 10:73-81
The haemoglobinopathies are the most common monogenetic diseases in the world. They include the thalassaemias and sickle cell syndromes. The sickle cell syndromes encompass several abnormal haemoglobin variants, of which homozygosity for the sickle c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b609375d05df251bb865589a0fec7cd
https://doi.org/10.1177/1755738015626186
https://doi.org/10.1177/1755738015626186