Inhibiting FAK–Paxillin Interaction Reduces Migration and Invadopodia-Mediated Matrix Degradation in Metastatic Melanoma Cells

Autor: Mousson A, Legrand M, Steffan T, Vauchelles R, Carl P, Gies J, Lehmann M, Guy Zuber, De Mey J, Dujardin D, Sick E, Rondé P

Publikováno v: Cancers
Cancers, MDPI, 2021, 13 (8), pp.1871. ⟨10.3390/cancers13081871⟩
Cancers, Vol 13, Iss 1871, p 1871 (2021)
Europe PubMed Central
Volume 13
Issue 8

Simple Summary The focal adhesion kinase (FAK) is over-expressed in a variety of human tumors and is involved in many aspects of the metastatic process. This has led to the development of small inhibitors of FAK kinase function which are currently ev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::852649be8c9e87d5946c5d01d31fb0ed
https://www.mdpi.com/2072-6694/13/8/1871

CD47 update: a multifaceted actor in the tumour microenvironment of potential therapeutic interest.

Autor: Sick, E^1,2, Jeanne, A¹, Schneider, C¹, Dedieu, S¹, Takeda, K², Martiny, L¹

Publikováno v: British Journal of Pharmacology. Dec2012, Vol. 167 Issue 7, p1415-1430. 16p. 2 Diagrams, 1 Chart.

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IL4-induced epigenetic modifications block TLR-induced responses in microglia and converts them into tolerogenic antigen presenting cells

Autor: Zuiderwijk-Sick, E., Putten, C. van der, Pasini, E., Kuipers, H., Eggermond, M. van, Straalen, L. van, Kondova, I., Valk, P. van der, Amor, S., Elsen, P. van den, Bajramovic, J.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::69d4a54e4764aa4f629aa48f189af3b6
https://hdl.handle.net/1887/111651

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